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Acanya(TM) Gel, a New Treatment for Moderate to Severe Acne, Launched by Coria Laboratories
Date:3/6/2009

l showed a 55% mean reduction in inflammatory lesions and a 43% mean reduction in non-inflammatory lesions at Week 12. Furthermore, 39% of patients treated with Acanya Gel considered their moderate to severe acne to be 'clear' or 'almost clear' at Week 12, and importantly reported marked improvement as early as two weeks.

Tolerability: The incidence of adverse drug reactions was low and similar across all treatment groups. The majority (greater than or equal to 97%) were mild to moderate in severity. The following application-site adverse reactions occurred in less than 0.2% of patients treated with Acanya Gel: application-site pain (0.1%), application-site exfoliation (0.1%), and application-site irritation (0.1%). Given the potential for skin irritation with fixed combination products containing higher concentrations (>2.5%) of BPO, no patient on Acanya discontinued treatment because of local signs or symptoms of stinging, burning, itching, erythema, or scaling, and in no patient were these severe. Mean scores for each local sign/symptom were <1 (1=mild) and comparable to individual active ingredients and vehicle.

Patient Satisfaction: Patient satisfaction data collected in the Phase III program showed significantly greater mean satisfaction scores with Acanya Gel at Week 12 than with prior acne therapy. Indeed 81% of patients were 'satisfied' with Acanya Gel at the end of treatment.

Acne: Widespread Condition

Acne vulgaris is a common skin disorder affecting 40 to 50 million Americans, or about 85 percent of people, at some point in their lives. The disorder is thought to be caused by multiple factors. Overproduction of sebum, a normal oily substance on the skin surface, combined with dead skin cells that are abnormally shed from the hair follicle, lead to plugging of the follicle. This allows skin bacteria, Propionibacterium acnes, to multiply and cause inflammat
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SOURCE Valeant Pharmaceuticals International
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