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Acacia Pharma Initiates Phase II Study With APD403 in Chemotherapy Induced Nausea & Vomiting (CINV)
Date:10/30/2013

he potential to be an effective anti-emetic, particularly controlling nausea, the major unmet need.

Dr Gabriel Fox, Acacia Pharma's Chief Medical Officer commented: "We are delighted to be working with an outstanding international group of investigators, including some of the world's leading authorities on CINV. Our clinical sites are highly enthusiastic about investigating this promising potential addition to the anti-emetic armamentarium."

Acacia Pharma's CEO, Dr Julian Gilbert, added: "CINV is an incredibly debilitating condition. Although significant advances have been made in the management of vomiting, nausea remains a major issue. We believe APD403 is a good anti-vomiting agent and an excellent anti-nauseant, thereby having the potential to make a significant contribution to cancer care."

APD403 contains the currently marketed dopamine D2 /D3 antagonist amisulpride for the new, patent-protected, use of management of CINV. The active ingredient is also being developed as APD421 for the prevention of post-operative nausea & vomiting (PONV), with two pivotal Phase III clinical studies having been initiated recently.

About Acacia Pharma

Acacia Pharma (http://www.acaciapharma.com) is a pharmaceutical company focused on cancer supportive care, a rapidly developing commercial opportunity. The growth in the cancer supportive care market has been driven by the increasing incidence of cancer, the expansion of effective cancer therapies and the desire to improve both the effectiveness of treatment and the quality of life of cancer patients.

Acacia Pharma has generated a pipeline of product opportunities addressing a range of supportive care indications such as nausea & vomiting, xerostomia (dry mouth) and cachexia (muscle wasting) using a commercially driven approach to product discovery based on kno
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SOURCE Acacia Pharma
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