Navigation Links
Abbott's XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
Date:10/22/2007

In the major secondary endpoint of Target Vessel Failure (TVF), XIENCE

V continued to demonstrate statistical non-inferiority to TAXUS with an

observed 23 percent reduction in Target Vessel Failure for XIENCE V

compared to TAXUS (8.3 percent XIENCE V, 10.8 percent TAXUS) at one

year. Target Vessel Failure is a measure of re-treatment anywhere

within the target vessel and includes cardiac death or heart attack.

-- There was no evidence of a difference in either acute (30 day) or late

thrombosis rates between XIENCE V and TAXUS out to one year.

"To date, XIENCE V is the only drug-eluting stent system that has demonstrated a statistically significant improvement in event-free survival compared to another FDA approved drug-eluting stent in a pivotal randomized clinical trial," said Gregg W. Stone, M.D., of Columbia University Medical Center and the Cardiovascular Research Foundation, New York, principal investigator of the SPIRIT III clinical trial. "In SPIRIT III, the risk for patients on the important clinical endpoint of MACE -- cardiac death, heart attack or retreatment in the diseased artery area -- was approximately 43 percent lower with XIENCE V than TAXUS at 1 year. A reduction in MACE with Xience V compared to TAXUS was also present at 1 year in the smaller SPIRIT II trial, demonstrating that this is a robust, reproducible difference."

There was no evidence of a statistical difference between rates of stent thrombosis for XIENCE V or TAXUS out to one year in the SPIRIT III trial. Rates of late stent thrombosis at one year per protocol were 0.3 percent for XIENCE V and 0.6 percent for TAXUS. Rates of definite/probable late stent thrombosis at one year under ARC definition were 0.5 percent for XIENCE V and 0.6 percent for TAXUS.

A variety of SPIRIT III subgroup analyses showed additional observational evidence of favorable clinical and angiographic results for XIENCE V; however, the
'/>"/>

SOURCE Abbott
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Abbott Announces Continued Positive Results with Xience V Everolimus Eluting Coronary Stent in Spirit Clinical Trials
2. Abbotts Xience V Everolimus Eluting Coronary Stent Superior to Taxus Stent in Spirit III U.S. Pivotal Clinical Trial
3. New Study Suggests Better Patient Outcomes with CYPHER Sirolimus-Eluting Coronary Stent than with Taxus Stent in Real-World Clinical Settings
4. Efficacy of OrbusNeichs Genous Bio-Engineered R Stent Compares Favorably to Drug-Eluting Stents
5. Abbott Announces Positive Nine-Month Results From the Worlds First Clinical Trial of a Fully Bioabsorbable Drug Eluting Coronary Stent
6. Investigators Report COSTAR II Pivotal Drug-Eluting Stent Trial Results at EuroPCR 2007
7. SPIRIT Clinical Data Reaffirm Strength of Taxus and Promus Drug-Eluting Coronary Stent Systems
8. Medtronic Announces Positive Nine-Month Results for Endeavor Resolute Next Generation Drug-Eluting Stent at EuroPCR
9. Taxus VI Clinical Trial Demonstrates Positive Long-Term Outcomes for Moderate-Release Paclitaxel-Eluting Stent at Four Years
10. ARRIVE Registry Analysis Identifies Predictors of Stent Thrombosis in Real-World Use of Drug-Eluting Stents
11. Cypher Sirolimus-Eluting Coronary Stent Had Similar Results to Bypass Surgery and Better Outcomes Than Bare Metal Stents in Subgroup Analysis of Diabetic Patients With Multivessel Coronary Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... -- Ameritox,s Ingenuity Health, a leading provider of monitoring solutions ... the National Council of Behavioral Health annual conference in ... 25 percent of the samples collected from patients with ... antipsychotic medication. ... Medication nonadherence can ...
(Date:4/20/2015)... 2015 International Isotopes Inc. (OTCQB: INIS, ... with the following update on its business segments. ... Historically, INIS has produced and sold high-activity ... of sealed sources for medical and industrial applications.  ... security examination, and radiography.  Due to technical issues ...
(Date:4/20/2015)... NEW YORK , April 20, 2015 /PRNewswire/ ... insulin pump market will continue to be robust; ... increasing incidence of diabetes, expanding global markets, new ... growth, there are relatively steady market inhibitors, such ... and an increasing competitive environment. The healthcare market ...
Breaking Medicine Technology:Ingenuity Health Research Flags Potentially High Rate of Medication Nonadherence Among Those with Serious Mental Illness 2Ingenuity Health Research Flags Potentially High Rate of Medication Nonadherence Among Those with Serious Mental Illness 3International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 2International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 3International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 4International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 5Kalorama: Insulin Pump Market Growing Robustly 2Kalorama: Insulin Pump Market Growing Robustly 3
... HASCO Medical, Inc. (OTC Bulletin Board: HASC ... serves patients in Alabama, Florida, and Mississippi, today announced ... additional 8,000+ products available for immediate delivery. ... and affordable for patients throughout the United States to ...
... 25, 2011 Elekta,s MOSAIQ®* oncology electronic ... certification. Complete EMR certification officially validates the Elekta ... demonstrate Stage 1 meaningful use under the HITECH ... the Drummond Group,s Electronic Health Records Office of ...
Cached Medicine Technology:HASCO Medical Expands Online Offering 2Elekta's Oncology-Specific MOSAIQ Receives Complete ONC-ATCB EMR Certification 2Elekta's Oncology-Specific MOSAIQ Receives Complete ONC-ATCB EMR Certification 3
(Date:4/21/2015)... The University of Scranton has launched ... to answer the growing demand for professionals trained ... wellness profile for better individual, real-world care. , ... implementation of health services and systems. This is ... operations in the healthcare sector,” says Margarete Zalon, ...
(Date:4/21/2015)... (PRWEB) April 21, 2015 On ... the grand opening of its Center for Graduate ... Hollywood Presbyterian Hospital. The campus recently completed a ... the only thing that has administrators and students ... expanded from the Master of Science in Nursing, ...
(Date:4/21/2015)... Springs, FL (PRWEB) April 21, 2015 ... these are a few of the Earth Day topics ... As state and national leaders debate the affect of ... offers a variety of subject matter touching on the ... The compelling segments will delve into sustainable lifestyles, clean ...
(Date:4/21/2015)... This program provides physical therapists, ... occupational therapist assistants, teachers, and other school based ... children across the autism spectrum succeed in the ... Inc. , Used throughout the United ... yoga curriculum addresses learning and behavior issues across ...
(Date:4/20/2015)... Falls Church, VA (PRWEB) April 21, 2015 ... How Sponsors and CMOs Speed Production and Improve Compliance ... – 3:00 p.m. EDT, http://www.fdanews.com/qualitybydesign , The ... that are forcing them to do more with less. ... forcing sponsors and CMOs to finds ways to speed ...
Breaking Medicine News(10 mins):Health News:The University of Scranton Launches Online MS in Health Informatics 2Health News:The University of Scranton Launches Online MS in Health Informatics 3Health News:West Coast University Opens a Center for Graduate Studies 2Health News:West Coast University Opens a Center for Graduate Studies 3Health News:USM Studios’ Programming Focuses on the Environment 2Health News:ABC News Interviews Anne Buckley-Reen, Education Resources Inc. Faculty Member, on Yoga Therapy in the Classroom 2Health News:FDAnews Announces — Using Quality by Design to Improve Manufacturing: How Sponsors and CMOs Speed Production and Improve Compliance Webinar, May 7, 2015 2Health News:FDAnews Announces — Using Quality by Design to Improve Manufacturing: How Sponsors and CMOs Speed Production and Improve Compliance Webinar, May 7, 2015 3
... RBC Life Sciences (OTC Bulletin Board: RBCL) announced ... Price, to CEO effective January 1, 2009. Company founder, ... chairman of the board of directors.The promotion comes at ... of proprietary nutritional supplements, wound care and pain management ...
... Dental Network of America (DNoA) and Philips Consumer ... America Corporation (Philips), just signed an agreement, effective ... "DNoA Preferred Network" dentists in Illinois, Oklahoma and ... Sonicare(TM) product line."Partnering with Philips on offering the ...
... January 30th noon to 5PM in our new Hyundai Dealer showroom at 271 ... the first 50 to donate blood. , ... Wilmington, MA (PRWEB) January 5, 2009 -- Bill Dube ... blood as the recent ice & snow storms that hit New England have canceled ...
... China, Jan. 5 /PRNewswire-Asia-FirstCall/ -- China Nepstar Chain,Drugstore ... "the Company"), the largest retail,drugstore chain in China ... announced that its Board of Directors and the ... termination of a voting rights agreement which,assigned 30% ...
... foods consumed during pregnancy might protect against asthma and ... apple a day while you,re pregnant may indeed keep ... your unborn child. , Recent research suggests ... have lower rates of asthma. , And, mothers who ...
... Today,s fast-paced,demanding culture often makes it challenging to ... health. Karate, which is most commonly,recognized as a means ... to help anyone achieve a fit body; relieve stress; ... her leadership skills. , Karate ...
Cached Medicine News:Health News:RBC Life Sciences Promotes Industry Veteran John W. Price to CEO; Company Founder, Clinton Howard, Will Remain Chairman of the Board 2Health News:RBC Life Sciences Promotes Industry Veteran John W. Price to CEO; Company Founder, Clinton Howard, Will Remain Chairman of the Board 3Health News:Dental Network of America and Philips Sign Agreement to Offer Sonicare Products to Dental Providers 2Health News:Boston Hyundai Dealer Teams up With the Red Cross to Save Lives 2Health News:China Nepstar Chain Drugstore Terminates Voting Rights Agreement for Yunnan Subsidiary 2Health News:China Nepstar Chain Drugstore Terminates Voting Rights Agreement for Yunnan Subsidiary 3Health News:China Nepstar Chain Drugstore Terminates Voting Rights Agreement for Yunnan Subsidiary 4Health News:Prenatal Nutrition, Postnatal Allergy Protection 2Health News:Prenatal Nutrition, Postnatal Allergy Protection 3Health News:Karate For Your Body Announces Release of Volume One in Martial Arts DVD Training Series, 'Focusing On Fundamentals' 2
... The Bledsoe Wee Walker Pediatric ... low profile pediatric boot that ... unsurpassed support. Only two sizes ... cost. These sizes will fit ...
... is a shorter and lighter version ... second degree ankle sprains, toe and ... Bledsoe EZ Set Mid-Calf Boot is ... 20 degrees of dorsi-flexion to 40 ...
... Diabetic Boot features a fully enclosed thick, ... unique auto-molding innersole which embeds into a ... aluminum shelled walking boot. This unique Automold™ ... distribute body weight across the entire bottom ...
... Bird and Cronin, ... manufacturer of Patient Footwear, ... Patient Care Products. Our ... highest quality and available ...
Medicine Products: