Navigation Links
Abbott's Phase III Sub-Group Analysis Shows Investigational TriLipix(TM) in Combination with CRESTOR(R) Improves Key Lipids in Patients with Mixed Dyslipidemia and Type 2 Diabetes
Date:6/7/2008

TriLipix in Combination with CRESTOR (rosuvastatin calcium) Demonstrates

Similar Lipid Effects in Patients with Diabetes and Overall Study

Population

SAN FRANCISCO, June 7 /PRNewswire-FirstCall/ -- New data from a sub-group analysis of patients with mixed dyslipidemia and type 2 diabetes that were enrolled in a Phase III study showed that the use of Abbott's investigational TriLipix(TM) (ABT-335) in combination with AstraZeneca's CRESTOR(R) (rosuvastatin calcium), demonstrated similar improvements in LDL "bad" cholesterol, HDL "good" cholesterol and triglycerides compared to the overall study population. These data were presented today at the American Diabetes Association's (ADA) 68th Annual Scientific Sessions in San Francisco.

Abbott evaluated the efficacy and safety of TriLipix in combination with rosuvastatin in a Phase III study of more than 1,400 patients with mixed dyslipidemia. This study, presented at the National Lipid Association annual meeting on May 31, 2008, met its primary endpoints. TriLipix in combination with rosuvastatin significantly improved HDL and triglycerides compared to rosuvastatin alone, and significantly improved LDL compared to TriLipix alone.

Of the patients enrolled in this study, a sub-group of 276 patients were identified as having type 2 diabetes. Data from this sub-group demonstrated that the comprehensive effect of TriLipix in combination with rosuvastatin was similar to that seen in the overall study population. Compared to corresponding monotherapies, patients receiving TriLipix in combination with rosuvastatin had significant decreases in triglycerides and LDL, in addition to clinically meaningful improvements in HDL.

Dyslipidemia affects millions of Americans living with diabetes. These patients often have mixed dyslipidemia, a complex combination of lipid problems commonly characterized by high triglycerides, low HDL and moderately high LDL.

"T
'/>"/>

SOURCE Abbott
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Type 2 Diabetes Patients Taking Exenatide Once Weekly, a Phase 3 Investigational Diabetes Therapy, Showed Improvements in Glycemic Control, Weight
2. Phase 3 Results for Alogliptin Demonstrated Significant Blood Sugar Reductions in Monotherapy and Four Add-on Therapy Studies
3. New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study
4. Synvista Therapeutics Reports Results of Three Phase 2 Clinical Trials of SYI-2074 in Diabetic Patients with Cardiovascular Disease
5. Phase 1/2 Trial of Motexafin Gadolinium Plus Antibody Targeted Radiation Therapy Demonstrates High Complete Response Rate in Patients With Non-Hodgkins Lymphoma
6. Nuvelo Initiates Phase 1B Clinical Trial of Anticoagulant NU172
7. Semafore Pharmaceuticals Reports Positive Interim Results from a Phase I Study of SF1126, a Targeted Pan-PI3K Inhibitor, in Patients with Advanced Solid Tumors
8. Celator(R) Pharmaceuticals Announces Positive Phase 2 Results for CPX-1 in Treatment of Colorectal Cancer
9. Keryx Biopharmaceuticals, Inc. Announces Phase 2 Results on KRX-0401 (Perifosine) in Patients with Relapsed/Refractory Waldenstroms Macroglobulinemia at the 44th Annual Meeting of the American Society of Clinical Oncology
10. Delcath Expands Phase III Trial for Metastatic Melanoma to Include St. Lukes Cancer Center
11. Kosans Lead Hsp90 Inhibitor, Tanespimycin, Shows High Level of Activity in Trastuzumab Resistant/Refractory HER2-Positive Breast Cancer in a Phase 2 Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... Technologies for Advanced Drug Delivery Systems -- ... http://www.reportlinker.com/p01940411/Global-Markets-and-Technologies-for-Advanced-Drug-Delivery-Systems----Focus-on-End-Users.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology STUDY OBJECTIVES ...
(Date:1/14/2014)... , Jan. 14, 2014 HeartWare International, ... innovator of less invasive, miniaturized circulatory support technologies that ... announced that it expects revenues for the fourth quarter ... full-year 2013 revenues to approximately $208 million. ...
(Date:1/14/2014)... 14, 2014 Dynamic Healthcare Services, Inc. ("DHS"), a portfolio ... acquired Progressive Home Medical Equipment, Inc. ("Progressive") of ... of the acquisition were not disclosed. Progressive ... a wide range of sleep, mobility, and respiratory products to ...
Breaking Medicine Technology:Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 2HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 3HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 4Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 2Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 3
... Care Group has become a pioneering educational member of ... ISVH,s primary aim is the achievement of high levels ... a whole. , Educational members of ISVH promote the ... protocols and recommendations for blood pressure monitoring to achieve ...
... Oct. 5 Kimberly-Clark Corporation (NYSE: ... Medical Company,s pain management business, which includes a number ... Care business has been the exclusive distributor of Baylis ... , The acquisition improves the competitive position of ...
Cached Medicine Technology:Fora Care Group Becomes Pioneering Educational Member of the International Society of Vascular Health 2Fora Care Group Becomes Pioneering Educational Member of the International Society of Vascular Health 3Fora Care Group Becomes Pioneering Educational Member of the International Society of Vascular Health 4Kimberly-Clark Acquires Baylis Medical Company's Pain Management Business 2Kimberly-Clark Acquires Baylis Medical Company's Pain Management Business 3
(Date:7/9/2014)... July 10, 2014 -- The World Health Organization recommends ... of moderate to vigorous physical activity (MVPA) each day. ... their MVPA during school hours. Therefore, it stands ... would increase MVPA. In a new study scheduled ... researchers confirmed that time spent outdoors after school was ...
(Date:7/9/2014)... the first time, researchers have access to detailed information ... health care. A new study, called Our Health Counts, ... challenges faced by urban Aboriginal people in Canada ... The findings, published today in BMJ Open , ... the general population. , Researchers interviewed 554 First Nations ...
(Date:7/9/2014)... Researchers at the Perelman School of Medicine at the ... Cancer Institute have received an $8 million grant from ... of photodynamic light therapy (PDT) in patients with malignant ... most often manifests itself in the lining of the ... asbestos. The grant will fund a clinical trial and ...
(Date:7/9/2014)... signals active in almost all types of cancer sends ... may help fuel a tumour,s uncontrolled growth, new research ... London, identified a molecular trigger responsible for ratcheting up ... factory that makes the building blocks cancer cells need ... signalling pathway, called SREBP, controls the flow of messages ...
(Date:7/9/2014)... researchers have uncovered mutations in a cell-signaling pathway that ... may expand treatments for patients because drugs targeting some ... in clinical trials. , Reporting July 9 in ... including researchers at Washington University School of Medicine in ... tumors from 230 patients with lung adenocarcinoma. , "This ...
Breaking Medicine News(10 mins):Health News:Go play outside! Outdoor time promotes physical activity in youth 2Health News:Urban Aboriginal people face unique health challenges 2Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Signal may send cancer's cellular factories into overdrive 2Health News:Lung cancer study hints at new treatments 2
... Researchers have reported that breast masses shown on ultrasound ... managed with imaging follow-up rather than biopsy. ... women from unnecessary, invasive biopsies, said Oswald Graf, M.D., ... Steyr, Austria. ,The American Cancer Society (ACS) ...
... Illicit Drug Trafficking is a global problem. It has ... global nuisance, the world would be best without. ... this nefarious trade, giving rise to powerful drug cartels ... have lent a blow to many peoples lives. Illicit ...
... plan to tackle child abuse in indigenous communities, ... to treatment before their welfare was taken away. ... of more than 60 Northern Territory communities and ... bans, welfare restrictions and compulsory health checks for ...
... release on Nintendo Co.'s Wii and Sony Corp.'s PlayStation 2, ... the game one after another, but it only seems to ... an amnesiac scientist and a psychotic killer from an asylum ... violent games become available for the Wii, the debate about ...
... A 32-year-old Afghan woman living in southwest Pakistan has given birth ... case for the country's huge refugee population, doctors said Monday. ... with their mother, identified as Amna Bibi, after they were born ... goes by one name. ,The proud father, who runs ...
... oil may be enough to prevent the loss of vision ... study has shown. ,When researchers gave tiny ... sardines, anchovies and other coldwater oily fish -- to mice ... which causes the condition decreased by 50 percent. ...
Cached Medicine News:Health News:Ultrasound Better Than Biopsy for Breast Examination 2Health News:This 'Grass' is Not Green - Say, 'No Thanks, I Am Fine Without Drugs' 2Health News:This 'Grass' is Not Green - Say, 'No Thanks, I Am Fine Without Drugs' 3Health News:An Indigenous Treatment Plan Offered by the Labor on Child Welfare 2Health News:Violent Videogames Attract Criticism Again 2Health News:Violent Videogames Attract Criticism Again 3Health News:Violent Videogames Attract Criticism Again 4Health News:Eating Fish Oil can Save Eyesight: Study 2
... simple intuitive programming and almost completely noiseless ... personal cycler in the modern laboratory workplace. ... self-adjusting heated lid allows a choice of ... a microplate of 5 x 5 in ...
... 96 temperature cyclers, the gradient block can be ... up to 14 or 22 across the 40- ... of up to 2C between adjacent wells in ... to 12 different annealing temperatures in a single ...
... includes: Mx3005P instrument and custom filter ... (5) filters. The standard filter set ... (535nm-555nm), ROX/Texas Red (585nm-610nm), Cy5 (635nm-665nm) ... computer, Mx3005P analysis software, Beacon Designer ...
... The SmartCycler System is a rapid, ... from prepared biological samples. By automating much ... reaction site individually programmable, it is the ... system now on the market. The SmartCycler ...
Medicine Products: