Navigation Links
Abbott's Ibis Technology Identified Fatal Disease Organism in Afghanistan
Date:2/7/2011

WASHINGTON, Feb. 7, 2011 /PRNewswire/ -- Today, at the American Society for Microbiology Conference on Biodefense and Emerging Diseases, scientists from Abbott Molecular presented data showing the unique power of the company's Ibis technology to identify and further characterize unknown disease-causing pathogens to help aid in the bioforensic analysis of pandemic outbreaks.  

In a presentation at the conference, Tim Motley, principal scientist, Ibis Biosciences, a subsidiary of Abbott (NYSE: ABT), reported on genotypic characterization of Yersina pestis after a severe outbreak of an unknown disease in Afghanistan's Nimorz Province in December 2007.  Eighty-three people experienced severe fever, vomiting and diarrhea, and 17 died.  All had consumed camel meat.  Due to the gastrointestinal symptoms and disease severity, anthrax was suspected.

Blood from a patient sample and several camel tissue specimens were analyzed using the Ibis T5000 biosensor, a precursor to the PLEX-ID™ system developed and marketed by Abbott.  The analysis showed both the blood and camel tissue specimens tested positive for Yersina pestis, the causative agent for plague.  This was the first reported case of plague in Afghanistan.  Other test methods, including culture, had failed to identify the causative organism.  

"With the PLEX-ID technology, we were able to genetically characterize the strain, identify its unique genetic structure and develop a microbial forensic marker that could be used to identify this strain should future outbreaks occur," said Motley.  He added that the ability of PLEX-ID to combine polymerase chain reaction (PCR) and electrospray ionization mass spectrometry allows laboratories to identify an unknown organism and determine its specific genotype.

Motley explained that the Afghanistan case shows the broad applicability of PLEX-ID technology for use in identifying and characterizing infectious agents before they become widespread.  

About PLEX-ID

Currently intended for non-diagnostic use, PLEX-ID is the only high-throughput technology that offers rapid and broad identification, detailed genotyping and characterization, and recognition of emerging organisms. The system employs a combination of molecular technologies, including polymerase chain reaction (PCR) for gene amplification and mass spectrometry analysis to rapidly characterize known and unknown organisms.  

It is designed to address a significant unmet need by providing test results in less than eight hours instead of three or more days required with current blood and tissue culture-based methods.

PLEX-ID is designed to identify a broad range of bacteria, viruses, fungi, certain parasites, and also provide information about drug resistance, virulence, and strain type.  Anticipated public health and biodefense applications include epidemiologic research and identification of emerging or previously unknown agents.  In addition, the system is being used for forensic characterization of human samples.

In 2009, PLEX-ID was recognized by both The Scientist and the Wall Street Journal as top scientific innovations of the year.  The Scientist honored the system because it can detect and characterize a broad range of microorganisms in any given sample.  The Journal selected PLEX-ID as its Gold winner of the 2009 Wall Street Journal Technology Innovation Awards because it promises to alert health officials to new disease strains, may also guard against bio-terrorism, and enable hospitals to identify antibiotic-resistant bacteria in its environment.

Since its development in 2005, PLEX-ID technology has been deployed in 20 sites around the United States, including the Centers for Disease Control and Prevention and the U.S. Food and Drug Administration.

About Abbott

Abbott is a global, broad-based health care company devoted to the discovery, development, manufacture and marketing of pharmaceuticals and medical products, including nutritionals, devices and diagnostics.  The company employs nearly 90,000 people and markets its products in more than 130 countries.

Abbott information is available on the company's Web site at www.abbott.com.


'/>"/>
SOURCE Abbott
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Inovio Pharmaceuticals Unveils Needle-free, Contactless Electroporation Technology for DNA Vaccine Delivery
2. Endologix Announces Favorable Clinical Results for Nellix Technology
3. University of Southampton and Inovio Pharmaceuticals Initiate Phase 2 Clinical Study to Evaluate Leukemia DNA Vaccine Using Electroporation Delivery Technology
4. US Army Study Shows STB Lifesaving Technologys® FAST® Dressing Superior to the Most Effective Currently Available Agents for Controlling Arterial Bleeding
5. Weikang Bio-Technology Announces Inclusion of Ranitidine Hydrochloride Capsule on National Drug Reimbursement List
6. Soligenix Executes Exclusive License with the University of Colorado for Vaccine Thermostabilization Technology
7. Crestwood Technology Group Receives Silver Boeing Performance Excellence Award
8. Wound Management Technologies Announces Secure eHealth Technology to be Included During HIMSS 2011 Interoperability Showcase
9. Encinitas Nursing and Rehabilitation Center First in Southern California to Deploy Voice Technology for Outcomes-Based Care
10. Frost & Sullivan Recognizes BeClose as a Technology Innovator for Aging Independently in North America
11. Medizone Internationals Mass-Market Sterilization Technology to be Produced by Canadian Medical Device Heavyweights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... , March 24, 2017 A ReportsnReports.com report ... been growing rapidly as the global sales of Adcetris and Kadcyla ... in the antibody drug conjugates market is driven by large number ... and wider therapeutic window offered by ADCs. ... Browse 3 Tables and 94 Figures, 10 ...
(Date:3/24/2017)...  GenomeDx Biosciences today announced that six abstracts featuring ... Cancer Classifier tests will be presented at the 32 ... held March 24 to 28, 2017 in ... Europe,s largest urological event showcasing ... field. The abstract titled "Muscle invasive bladder ...
(Date:3/24/2017)... 2017  Provectus Biopharmaceuticals, Inc. (OTCQB: PVCT, ... oncology and dermatology biopharmaceutical company, today disclosed terms ... Sheet (the "Definitive Financing") it entered into on ... stockholders, who are referred to in the Definitive ... filed with the Securities and Exchange Commission.   ...
Breaking Medicine Technology:
(Date:3/24/2017)... ... 2017 , ... As the standards bearer of advanced cancer ... positions them as the go-to thought leader in all matters concerning oncology nursing. ... always-on, always-fresh news, views and advocacy engine, called ONS Voice. , The ONS ...
(Date:3/24/2017)... Westchester County, NY (PRWEB) , ... March 24, 2017 , ... ... in Somers and White Plains, N.Y., is pleased to announce Westchester resident Lauren C. ... as a law clerk for the firm, will concentrate her practice in elder law, ...
(Date:3/24/2017)... ... 24, 2017 , ... Empower Brokerage, located in Southlake, Texas, ... programs. , In February, 2017, Empower Brokerage introduced their new “Performance Partners” program ... to teach how to maximize their sales efforts, as well as how to ...
(Date:3/24/2017)... ... ... Time GPS”: a dauntless and enlightened study of the second-coming of Christ, and ... published author, Wesley Gerboth, a World War II veteran, with a highly-regarded reputation as ... ninety-one, he shares the Wisdom God bestowed upon him in this publication. , ...
(Date:3/24/2017)... , ... March 24, 2017 , ... “The Adventures of ... smart and silly dog who lives his life to the fullest, as God intended. ... published author Patti Holmgren, a mother and grandmother pursuing her passion for writing, especially ...
Breaking Medicine News(10 mins):