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Abbott to Present Data on Several Investigational Cancer Treatments at American Society of Clinical Oncology Annual Meeting
Date:6/3/2010

loma: A phase 1 study; A.J. Jakubowiak.

  • Abstract 1702; Novel Therapies for Myeloma, oral presentation; June 5, 2010; 4:30 p.m.6 p.m.; Location: E354a; Presentation time: 5:30 p.m.

Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma: A phase I/II study; S. Lonial.

  • Abstract 1703; Myeloma session, oral presentation; June 6, 9:30 a.m.12:30 p.m.; Location: Rm E354b; Presentation time: 12 p.m.

Abbott's Oncology Research

Abbott's current pharmaceutical oncology research is focused on developing more targeted, less toxic therapies that improve survival and quality of life for patients living with cancer. Abbott's pipeline addresses multiple phases of cancer progression and targets processes that cancers need to survive, including programmed cell death (apoptosis), new blood vessel formation (angiogenesis) and travel throughout the body (metastasis).

Kinase Inhibitors (linifanib) – Linifanib is an oral small molecule that provides both potent and specific inhibition of the VEGFR and PDGFR families. Inhibition of the appropriate kinases can suppress tumor growth by preventing the formation and spread of new blood vessels that supply the tumor with oxygen and nutrients, and by inhibiting key angiogenic signaling pathways. Linifanib is in Phase III clinical trials for hepatocellular carcinoma (HCC) and ongoing Phase II trials in renal cell cancer (
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