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Abbott to Present Data on Several Investigational Cancer Treatments at American Society of Clinical Oncology Annual Meeting
Date:6/3/2010

of cancers and, by focusing on some of the most promising areas of cancer research, including bcl-2 and PARP inhibition, Abbott scientists are targeting the processes cancers need to survive in order to advance new treatments.

Abbott data being presented includes two oral presentations on elotuzumab, an antibody designed to bind to the CS1 glycoprotein, a highly expressed cell surface protein in multiple myeloma. Four separate studies of linifanib (ABT-869), which is being studied as an inhibitor of the VEGFR and PDGFR kinase pathways, in advanced renal cell cancer (RCC), advanced solid tumors, advanced hepatocellular carcinoma (HCC) and non small cell lung cancer (NSCLC), also will be presented.

Abbott will also present results from a Phase 2 study of navitoclax (ABT-263) in small-cell lung cancer (SCLC) and independent researchers will present five studies on veliparib (ABT-888), a PARP-inhibitor, including phase 2 data in breast cancer.

Presentations include:

Linifanib (ABT-869)

Phase 2 trial of linifanib in patients with advanced renal cell cancer (RCC) after sunitinib failure; Tannir et al.

  • Abstract 4527; Poster Discussion; June 5, 2010; 2 p.m. - 6 p.m.; Location: E540a; Poster number: 8.
  • Discussion: 5 p.m.6 p.m. in EHall D2.

Linifanib treatment in patients with non small cell lung cancer (NSCLC); Phase 2 results; R. A. Soo, et al.

  • Abstract 7590; Poster Session; June 6, 2010; 8 a.m. &#
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