Navigation Links
Abbott to Collaborate With GSK on Molecular Diagnostic Test to Select Candidate Patients for Future Skin Cancer Immunotherapy
Date:3/3/2010

tients who may benefit from a skin cancer treatment in development by GSK.

GSK's MAGE-A3 ASCI (Antigen-Specific Cancer Immunotherapeutic) candidate is currently being evaluated as an adjuvant treatment in melanoma biopsy specimens in the Phase III clinical study DERMA.  To be eligible to receive GSK's MAGE-A3 ASCI, patients must have MAGE-A3 expressing melanoma tumors.  

Under terms of the agreement, Abbott, in conjunction with GSK, will develop and commercialize a PCR (polymerase chain reaction) test for use on the Abbott m2000™ automated molecular instrument system.  The test will be designed to detect MAGE-A3, a tumor-specific antigen that is expressed in skin cancer and a wide variety of other cancers, but not in normal cells.  In July 2009, both companies announced a similar collaboration and Phase III investigation for the MAGE-A3 marker in non-small-cell lung cancer.

Currently, there are no nucleic acid-based tests approved by the U.S. Food and Drug Administration for use in identifying patients who may derive treatment benefits from targeted skin cancer therapies.  Abbott, in collaboration with GSK, will seek regulatory approval for the test in several markets, including the United States and Europe. '/>"/>

SOURCE Abbott
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Abbott Receives Supplemental FDA Approval for its Best-in-Class in Sensitivity RealTime HIV-1 Viral Load Test
2. Abbott and AstraZeneca Announce Selection of Next-Generation Fenofibrate ABT-335 and CRESTOR(R) Fixed-Dose Combination
3. Abbott Initiates Clinical Study to Evaluate Use of RX Herculink(R) Elite(TM) Renal Stent System for the Treatment of Renal Artery Stenosis
4. Abbotts ABT-874 Shows Positive Results for Maintenance of Response in Phase II Psoriasis Study
5. Abbotts XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
6. Abbott Announces Positive One-Year Results from the Worlds First Clinical Trial of a Fully Bioabsorbable Drug Eluting Coronary Stent
7. Abbotts m2000(TM) Molecular Diagnostic Instrument and RealTime HIV-1 Test Win Chicago Innovation Award
8. Abbotts HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis
9. Abbotts XIENCE(TM) V Drug Eluting Stent Demonstrates Consistent and Positive Clinical Outcomes Out to Two Years
10. Abbotts Phase III Studies of Investigational TriLipix(TM) (ABT-335), in Combination With Statins, Meets Primary Endpoints on Improving LDL, Triglycerides and HDL
11. Study in JAMA Shows Patients Treated With Abbotts XIENCE(TM) V Drug Eluting Stent Experience Better Outcomes Than Patients Treated With Market-Leading Drug Eluting Stent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... , July 25, 2014  Acsis Inc., ... protection and serialization solutions, has recently posted an ... that addresses current and future needs for companies, ... the old supply chain model no longer work ... technology, including the growth of mobile technology, machine ...
(Date:7/25/2014)... , July 25, 2014 Research ... "Global Ophthalmic Diagnostic Devices Market 2014-2018" report ... About Ophthalmic Diagnostic Device ... used to identify a defect or deficiency in the ... with ophthalmic disorders such as presbyopia, cataracts, glaucoma, retinal ...
(Date:7/25/2014)... July 25, 2014 Leading events organizer ... returning for the seventh year to São Paulo, ... August 2014. The event will co-locate with Food Ingredients ... most comprehensive meeting point for the pharmaceutical industry. ... countries for pharmaceutical sales are now exploring the ...
Breaking Medicine Technology:Acsis Addresses Questions on the Modern Supply Chain 2Global Ophthalmic Diagnostic Devices Market 2014-2018: Key Vendors are Alcon, Carl Zeiss, Haag-Streit and Topcon 2CPhI South America 2014 Launches with Generics Showing Huge Growth 2CPhI South America 2014 Launches with Generics Showing Huge Growth 3CPhI South America 2014 Launches with Generics Showing Huge Growth 4
(Date:7/25/2014)... genes are switched on or off plays a key ... metabolism, UT Southwestern Medical Center researchers have found., The ... obesity and diabetes, since the transcription factor involved ... influence the body,s sensitivity to insulin and leptin signaling. ... regulation of food intake and sugar disposal, and obesity ...
(Date:7/25/2014)... Innerspire, LLC ( http://www.innerspire.com ) announced ... a Creative Enrollment Specialist. In this role, Greg will ... well as his accomplished design skills to further develop ... to service the creative marketing needs of ... with small business owners and individuals looking to accelerate ...
(Date:7/25/2014)... 2014 The American Brain Tumor Association ... “ABTA CommYOUnity™” during its annual patient and family conference ... the brain tumor community as we – the first ... support services and funding brain tumor research – extend ... brain tumor awareness and getting our materials and services ...
(Date:7/25/2014)... 25, 2014 There are 700,000 people in ... each day. Though when someone hears the words, “you have ... unsure of the next step and where to turn. , ... out that next step by providing and pursuing the answers ... Brian Olson, member of the ABTA’s Board of Directors and ...
(Date:7/25/2014)... July 25, 2014 Progress in understanding ... a new era of promising brain tumor treatments, according ... School, director of the Center for Neuro-Oncology, Dana-Farber Cancer ... annual Patient and Family Conference in Chicago, July 25-26, ... and new technology are impacting the development of new ...
Breaking Medicine News(10 mins):Health News:Manipulating key protein in the brain holds potential against obesity and diabetes 2Health News:Innerspire, LLC Continues National Expansion 2Health News:Innerspire, LLC Continues National Expansion 3Health News:Innerspire, LLC Continues National Expansion 4Health News:American Brain Tumor Association Unveils Brand Identity for Newly Launched Volunteer Network 2Health News:American Brain Tumor Association Unveils Brand Identity for Newly Launched Volunteer Network 3Health News:American Brain Tumor Association Board of Directors Member Shares Story of Brain Tumor Survivorship 2Health News:American Brain Tumor Association Board of Directors Member Shares Story of Brain Tumor Survivorship 3Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 2Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 3Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 4
... a small amount of chocolate had lower risks of heart ... Failure , a journal of the American Heart Association. The ... looked at the relationship of the amount of high-quality chocolate ... The quality of chocolate consumed by the women had a ...
... they detect and treat drug-resistant staph infections, but most ... University of Illinois at Chicago. Researchers sent a ... in the U.S. to learn of their policies and ... All of the hospitals are members of Broadlane, a ...
... cells that are vital for airway repair in the lung ... are associated with a poor prognosis in patients who develop ... Jonsson Comprehensive Cancer Center have found. These adult stem ... are found in pre-cancerous areas, suggesting that these cells may ...
... has examined how a specialized Iyengar yoga program for women ... treatment, makes a difference in their recovery. For two ... a questionnaire about their physical and mental health at the ... at the end. After analyzing the data that was collected ...
... University Massey Cancer Center researchers have uncovered a new ... not always cause inflammation, chronic inflammation is known to ... published in the June issue of Nature , ... Ph.D., and their co-authors examine how sphingosine-1-phosphate (S1P), a ...
... , MONDAY, Aug. 16 (HealthDay News) -- The ... poses a health threat to clean-up workers, fishermen and members ... have examined the area. "Clinicians should be aware of, ... and related chemicals. Symptomatic patients should be asked about occupation ...
Cached Medicine News:Health News:Moderate chocolate consumption linked to lower risks of heart failure 2Health News:Moderate chocolate consumption linked to lower risks of heart failure 3Health News:MRSA policies differ among hospitals, study shows 2Health News:Lung stem cells vital to lung repair associated with poor cancer prognosis when found in tumor 2Health News:VCU Massey research finds new link between inflammation and cancer 2Health News:Gulf Oil Spill Still a Health Threat to Many, Researchers Report 2Health News:Gulf Oil Spill Still a Health Threat to Many, Researchers Report 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: