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Abbott Statement on the FDA Advisory Committee Recommendation on Sibutramine
Date:9/15/2010

their doctor while they are taking Meridia.

People should not take Meridia if they have severe liver or kidney disease, are pregnant or planning to get pregnant or if they are nursing.

Patients should tell their doctor if they have or ever have had glaucoma, kidney or liver problems, seizures, bleeding problems, gallstones or depression, are pregnant or planning to become pregnant, or are breastfeeding.

Using Meridia with certain other medicines may affect how Meridia or the other medicines work.  Patients should tell their doctor about all the medications they take, including prescription and non-prescription medicines, vitamins and herbal supplements.  Patients should especially tell their doctor if they take: a monoamine oxidase inhibitor (MAOI) medicine, other weight loss medicines, cough and cold medicines, migraine headache medicines, medicines used to treat depression, narcotic pain medications, lithium, tryptophan, or medicines that thin the blood.

Meridia may cause serious side effects, including:

  • Serotonin syndrome, which may happen when people take Meridia with certain other medicines that affect a brain chemical called serotonin.  Patients should not take other medicines with Meridia unless their doctor has told them to.  Patients should get medical help right away if they have any of the following symptoms:
  • feel weak, restless, confused or anxious
  • lose consciousness (faint)
  • have a fever, vomiting, sweating, shivering or shaking
  • have a fast heart beat
  • seizures (convulsions, fits)
  • bleeding.  Bleeding may happen if patients have a condition that causes bleeding or if they take a blood thinning medicine.

  • Certain weight loss medicines have a rare but life-threatening problem that affects blood pressure in the lungs (pulmonary hypertension).  It is not known if Meridia may cause this problem.  Patients should call their d
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