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AXIOS™ Stent and Delivery System Study Demonstrates Successful Treatment of Pancreatic Pseudocysts and Acute Cholecystitis
Date:5/15/2012

MOUNTAIN VIEW, Calif., May 15, 2012 /PRNewswire/ -- Xlumena, Inc. announces the publication of a scientific paper describing the first human study of the AXIOS™ Stent and Delivery System. The article, entitled "Clinical evaluation of a novel lumen-apposing metal stent for endosonography-guided pancreatic pseudocyst and gallbladder drainage" appeared in the April issue of Gastrointestinal Endoscopy – the leading journal for advances in endoscopy.

The research reports technical and clinical success using the AXIOS Stent to treat 15 pancreatic pseudocyst and 5 acute cholecystitis patients. All the pseudocysts and cholecystitis symptoms resolved and did not recur during the 9 month follow-up period. There were no complications during stent placement or removal.

Pancreatic pseudocysts are painful and potentially dangerous fluid-filled sacs most often resulting from pancreatitis. They can be treated surgically, percutaneously or endoscopically. Cholecystitis, or inflammation of the gallbladder, is usually alleviated by surgically removing the gallbladder. Patients who cannot undergo surgery have only the uncomfortable option of having a percutaneous (external) drain inserted into their gallbladder.

"This study demonstrates the promise of the AXIOS Stent," says Takao Itoi, MD of Tokyo Medical University Hospital and the paper's lead author. "We were able to successfully treat these very sick patients endoscopically and enable them to avoid more invasive procedures."

The stent provides a new approach for gallstone removal. "Two patients in the trial had gallstones. In one of these the stones came out on their own through the stent and in the other we were able to remove the stones. This is a unique and potentially clinically important development," adds Dr. Itoi.

Also interesting is that one cholecystitis patient in the study refuses to have the stent removed. "She had undergone frequent and repeated intervention
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SOURCE Xlumena, Inc.
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