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AVAC Says MDP 301 Microbicide Trial Results Disappointing, but Researchers and 9,400 Trial Volunteers Deserve Praise for Successful Trial
Date:12/14/2009

Funding and Support for HIV Prevention Research Must Continue

NEW YORK, Dec. 14 /PRNewswire-USNewswire/ -- The Microbicides Development Programme announced earlier today that its MDP 301 effectiveness trial, which was conducted among almost 9,400 women in four African countries, found no evidence that the PRO 2000 microbicide reduces the risk of HIV infection.

Reacting to today's announcement, AVAC executive director Mitchell Warren said, "Of course, we are disappointed to hear these results, since we always hope that such a trial will actually prove effectiveness. Yet we are confident that MDP 301, because it was so well implemented, provides vital information to help researchers and communities move forward in the search for safe and effective microbicides."

Although this product had looked promising in animal studies and in earlier human studies, the MDP 301 trial provided a clear answer that this product does not work. "But it is just as clear that this is by no means the end of the line for microbicide research," Warren added. "Around the world today, thousands of researchers and trial participants are continuing the important work of discovering and testing other, more potent microbicide candidates as well as additional biomedical prevention options. Scientists, funders, advocates and others in the field must now ensure that key lessons learned from this trial are incorporated into developing better products and into planning for new trials."

A trial of this complexity and magnitude is a great accomplishment in the effort to stem the tide of the HIV pandemic. Everyone involved, especially the trial staff and volunteers, deserve thanks and credit for their dedicated efforts and important contributions.

"We especially want to thank the more than 9,300 heroic women who have participated in this trial. Each one of these volunteers and their communities made a significant cont
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SOURCE AIDS Vaccine Advocacy Coalition
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