Navigation Links
ANA598 Demonstrates Positive 4-Week Results at 200 mg BID
Date:12/17/2009

encouraging for the prospects of ANA598 contributing to improved long-term treatment outcomes as measured by SVR."

In the ongoing Phase II study, patients are to receive ANA598 or placebo, added to SOC, for 12 weeks, after which they are to continue receiving SOC alone for 12 or 36 additional weeks. The results announced today are from a scheduled interim analysis following four weeks of dosing in the first of two planned dose cohorts. 44 patients in the first cohort (34 genotype 1a and 10 genotype 1b) received at least one dose of study medications, 29 receiving ANA598 and 15 receiving placebo. Two patients who withdrew consent during the first week of dosing for reasons unrelated to ANA598 are excluded from the analysis of antiviral response but included in the safety database. Reported antiviral response data is as of week 4. Reported safety data is as of an interim analysis date which was reached shortly after the last enrolled patient completed four weeks of dosing, and includes information through week 4 for all patients plus information subsequent to week 4 for those patients who had earlier enrollment dates.


    Preliminary Antiviral Response Assessment

                         total             genotype 1a        genotype 1b
                        patients            patients            patients
                    ANA598    Placebo   ANA598    Placebo   ANA598   Placebo
                     +SOC      +SOC      +SOC      +SOC      +SOC     +SOC
                    ---------------------------------------------------------
    RVR
    ---
    Percentage
     of Patients
     with
     Undetectable     56%        20%      50%        17%       71%       33%
     HCV RNA        (15/27)    (3/15)   (10/20)    (2/12)     (5/7)     (1/3)
     (<15 IU/ml)
     at Week 4

    VIRAL LOAD
     CHANGE
    ----------
    Mean Decline
     in HCV
     RNA (log10
     IU/ml) at
     Week 4            4.1       2.7       4.2       2.4     
'/>"/>
SOURCE Anadys Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Anadys Pharmaceuticals Presents Preclinical Results on ANA598, a Non-Nucleoside Inhibitor of the NS5B Polymerase, at the 14th International Symposium on Hepatitis C Virus and Related Viruses
2. Anadys Pharmaceuticals Announces Positive Results for ANA598 in Animal Model of Chronic Hepatitis C Virus Infection
3. Anadys Pharmaceuticals Presents Data on ANA598, a Non-Nucleoside Inhibitor of the HCV Polymerase, at the 21st International Conference on Antiviral Research
4. Anadys Pharmaceuticals Initiates Phase I Clinical Trial of ANA598
5. Anadys Pharmaceuticals Announces Successful Outcome of ANA598 Healthy Volunteer Study and Finalization of Study Design for Phase Ib Trial in HCV Patients
6. Anadys Pharmaceuticals Announces Single Dose Safety and Pharmacokinetics Results for ANA598 in Healthy Volunteers
7. ANA598 Demonstrates Potent Antiviral Activity in an Early Clinical Study in HCV-Infected Patients
8. ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients
9. Anadys Pharmaceuticals Commences Dosing in Phase II Study of ANA598
10. Cytokine Demonstrates Oral Efficacy of Small-Molecule MIF Inhibitors
11. Lpath Demonstrates Strong Safety Profile of Lead Drug Candidate, Sphingomab(TM), in Non-Human Primates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... 2015 ResMed Inc. (NYSE: RMD ) today ... year ended June 30, 2015 results on Thursday, July 30, ... press release with ResMed,s results will be issued after 1:00 ... webcast to discuss operating results and future outlook. ... US Pacific Time and the live webcast of the call ...
(Date:7/2/2015)... Roche,s Bloodhound technology is on the ... hematology testing, according to Kalorama Information.  The healthcare ... its Bloodhound digital cell imaging technology –as newly ... hematology analyzer – is notable as a play ... leader CellaVision, but also compete more broadly in ...
(Date:7/2/2015)... 2015  The Green Exchange, Inc., the developer,s of ... compliant mobile app that connects cannabis growers directly to ... announced today that their service provides the fastest delivery ... more than half a dozen other delivery apps that ... is unique in that it connects growers directly ...
Breaking Medicine Technology:ResMed to Announce Fourth Quarter and Fiscal Year-End 2015 Results 2Kalorama: With Bloodhound, Roche Closes in on High-Growth Hematology Segment 2Kalorama: With Bloodhound, Roche Closes in on High-Growth Hematology Segment 3New Cannabis Delivery App Gets Product to Patient in Under 7 Minutes 2
... ARAY ), the premier radiation oncology company, announced ... October 3, at the annual meeting of the American Society ... is open to institutional investors and research analysts. ... a.m. E.D.T. on Monday, October 3 at the W Hotel, ...
... Landauer, Inc. (NYSE: ... appointed, Michael T. Leatherman, as the Company,s Interim Chief Financial ... principal accounting officer, effective September 9, 2011. Leatherman succeeds Jonathon ... has left the Company in order to accept the chief ...
Cached Medicine Technology:Accuray Incorporated to Host Investor Meeting at ASTRO 2011 2Landauer Elects Board Member Michael T. Leatherman as Interim Chief Financial Officer 2
(Date:7/4/2015)... ... ... Dating a real millionaire online can be more difficult. Millionairematchapp.com is a ... the worries from meeting partners. Recently, the site announced they're publishing of a ... have responded with excitement. , “There's quite a few millionaire dating apps online, ...
(Date:7/4/2015)... ... July 04, 2015 , ... ... industry’s leading recognition of technical sales expertise from the North American Board of ... ProfessionalTM. NABCEP is the most highly respected and well established national certification organization ...
(Date:7/3/2015)... Greenville, SC (PRWEB) , ... ... ... Society has announced the sessions and speaker lineup for its 2015 ... nursing, taking place August 6-8, 2015 at the Renaissance Orlando at SeaWorld ...
(Date:7/3/2015)... ... July 03, 2015 , ... ... providers, has been retained to lead a national chief nursing officer recruitment ... executive search firms in the healthcare industry, B. E. Smith has recently placed ...
(Date:7/3/2015)... , ... July 03, 2015 , ... Jennifer Renee Hanes, ... Choice Emergency Room , the largest network of independent freestanding emergency rooms in the ... medical director of our Sienna Plantation facility,” said Executive Medical Director of First Choice ...
Breaking Medicine News(10 mins):Health News:MillionaireMatchapp.com Publishes the Best Millionaire Dating App and Official Dating Site Reviews 2015 2Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 2Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 3Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3
... officials add hot peppers and cilantro as suspect foods, ... -- The number of people sickened in the ongoing ... types of tomatoes remain the suspected cause, U.S. health ... potential suspects as well. , "We continue to ...
... Peake: Provide Counseling for All Combat Veterans, WASHINGTON, ... other assistance in 39 additional,communities across the country where ... by fall 2009., "Community-based Vet Centers -- already ... VA,s mental health program," said Dr. James B. Peake,Secretary ...
... People are more likely to be,active in the summertime ... -- than at any other time of the year. ... at their peak. Natural Solutions: Vibrant,Health Balanced Living magazine ... just in time for the dog days ahead. The ...
... years of publishing groundbreaking research, the June issue of ... pivotal research and significant discoveries in the field of ... without charge from HFES., For over half a century, ... safety and efficiency of systems, environments, tools, and products. ...
... Calif. Children,s Hospital Oakland,s research institute is ranked ... National Institutes of Health to children,s hospitals. In 2007, ... awards from the NIH. This feat was accomplished with ... institute,s grants second in the nation. , ...
... inspire better performance by pressuring their teams. Now, proteomics ... their analyses. In a simple solution to a time-consuming ... in their protocol squeezes four hours of waiting into ... see how well it worked," said biochemist Daniel Lopez-Ferrer, ...
Cached Medicine News:Health News:Salmonella Illnesses Now Largest Foodborne Outbreak in U.S. History 2Health News:Salmonella Illnesses Now Largest Foodborne Outbreak in U.S. History 3Health News:VA Vet Centers Coming to 39 Communities 2Health News:Stay Safe This Summer With Chemical-Free Sunscreen and DEET-Free Bug Repellent, Says Natural Solutions Magazine 2Health News:Human Factors Journal celebrates 50 years 2Health News:Pressured proteins: A little pressure in proteomics squeezes 4-hour step into a minute 2Health News:Pressured proteins: A little pressure in proteomics squeezes 4-hour step into a minute 3
... patent pending solution using Radio Frequency ... smart label to promote patient safety ... wrong-procedure surgery. This simple to use ... surgeon with the operating room staff ...
... provide healthcare professionals witha patient'sname and ... speak, cant remember, oris unconscious. VeriMed ... individuals. The application can help these ... comparable level of care by rapidly ...
Computer-generated Smart CompuBand can be simultaneously printed with bar code information and programmed with RFID information...
... The HALO Infant Protection System helps ... equipment to ensure the operating efficiencies, cost ... even in todays busy and constrained healthcare ... getting the most reliable and versatile solution, ...
Medicine Products: