Navigation Links
AMT Prepares for Submission of Marketing Authorization Dossier for AMT-011 (Glybera(R))
Date:6/12/2008

AMSTERDAM, June 13 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today that it has concluded enrollment and treated the last patient in the pivotal trial for it's lead product AMT-011 (Glybera(R)) for Hyperlipoproteinemia, a seriously debilitating and potentially lethal disease. After recent preparatory meetings with the rapporteur countries Germany and the United Kingdom of the European Medicines Agency (EMEA), AMT expects to file the Marketing Authorization Dossier with EMEA not later than the fourth quarter of 2008.

AMT has developed AMT-011 as a cure for patients with the rare genetic disorder Hyperlipoproteinemia (HPL) type I, also known as LPL-deficiency. These patients have extremely high fat levels in their blood resulting in recurrent and potentially lethal pancreatitis as well as an increased risk of cardiovascular complications and diabetes. Because of a defective gene HPL-patients do not produce an enzyme that normally breaks down fats in the blood. Currently, there is no effective treatment or cure for this seriously debilitating and potentially lethal disease.

AMT-011 is a gene therapy product designed to insert a healthy gene into the patient's body to replace the defective gene. The product is administered by a series of injections into muscle tissue after which the body starts to make the missing enzyme again. The advantage of this therapy is its potential to cure a disease instead of just treating the symptoms. AMT expects to finish the ongoing clinical trial with AMT-011 according to plan.

About Amsterdam Molecular Therapeutics

AMT has a unique gene therapy platform that to date appears to circumvent many if not all of the obstacles that have prevented gene therapy from becoming a mainstay of clinical medicine. Using adeno-associated viral (AAV) vectors as the delivery vehicle of choice for therapeutic genes, the company has been
'/>"/>

SOURCE Amsterdam Molecular Therapeutics B.V
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Columbia University Medical Center and Rosetta Genomics Announce Columbia Universitys Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
2. Synbiotics Corporation Announces Human Submission for FluDetect(R)
3. FDA to Extend Review of Data Quality Submission for Genasense(R) in Melanoma
4. PARIs eFlow Included in Gileads NDA Submission for Aztreonam Lysine for Inhalation
5. BD Announces FDA 510(K) Submission of Rapid Molecular Test to Identify Patients Carrying Staph Superbug Prior to Surgery
6. Indevus Announces Submission of New Drug Application
7. European Regulatory Agency Accepts Cell Therapeutics, Inc.s Marketing Authorization Application for XYOTAX(TM) for Lung Cancer for Review
8. Cell Therapeutics, Inc. (CTI) Submits European Marketing Authorization Application for XYOTAX(TM)
9. Infant Formula Manufacturers Again under Ethical Cloud: Marketing Gimmick Linked to Serious Illnesses
10. Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)
11. ADVENTRX Meets Primary Endpoint in ANX-530 Marketing-Enabling Clinical Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2014)... July 21, 2014 Galmed Pharmaceuticals Ltd. (Nasdaq: ... focused on the development and commercialization of a once-daily, ... cholesterol gallstones, announced today that it will host a ... to discuss results for the period ended June 30, ... with respect to its clinical program for aramchol. ...
(Date:7/21/2014)... Sorrento Therapeutics, Inc. (NASDAQ: SRNE ... treatments for cancer and its associated pain, today announced ... development of a small molecule inhibitor targeting the important ... protein has also been recognized as an important determinant ... as a dominant factor in most human cancers and ...
(Date:7/21/2014)... MARYVILLE, Ill. , July 21, 2014 /PRNewswire-iReach/ ... that Dr. Ryan Diederich has been ... on Membership and Advocacy for 2014-2015. This council ... member resources, services and benefits. The ... that represents and unifies its physician members as ...
Breaking Medicine Technology:Galmed Pharmaceuticals Second Quarter 2014 Conference Call and Webcast Scheduled for Friday, July 25, 2014 2Sorrento Awarded Grant from the National Institutes of Health for the Development of a Small Molecule Myc Inhibitor 2Sorrento Awarded Grant from the National Institutes of Health for the Development of a Small Molecule Myc Inhibitor 3Sorrento Awarded Grant from the National Institutes of Health for the Development of a Small Molecule Myc Inhibitor 4
... Dec. 21, 2011  VIVUS, Inc. (NASDAQ: VVUS ... retrospective study of medical claims data on oral ... utero .  The study, known as FORTRESS for ... mother-infant dyads exposed to topiramate either alone (monotherapy) ...
... Dec. 21, 2011 Despite the numerous medical advances ... the United States is still higher than most European ... the growing rate of pre-term births, researchers are committed ... Northwestern Medicine ® researchers are examining ...
Cached Medicine Technology:VIVUS Reports Topline Findings From FORTRESS 2VIVUS Reports Topline Findings From FORTRESS 3VIVUS Reports Topline Findings From FORTRESS 4VIVUS Reports Topline Findings From FORTRESS 5VIVUS Reports Topline Findings From FORTRESS 6Northwestern Researchers Trial New Device that May Support Improved Newborn Health 2Northwestern Researchers Trial New Device that May Support Improved Newborn Health 3Northwestern Researchers Trial New Device that May Support Improved Newborn Health 4
(Date:7/22/2014)... With over 170,000 students now playing high school ... during practice and competition, according to a new study ... Center for Injury Research and Policy at Nationwide Children,s ... today by The American Journal of Sports Medicine ... injuries over the four academic years from 2008 through ...
(Date:7/22/2014)... 22, 2014 CareTouch Communications, Inc. has ... in the Community . CareTouch employees will select causes ... hands-on support in line with their mission to help ... The program’s first cause is Hike for Hospice, to ... On Sunday, September 14, the CareTouch in the Community ...
(Date:7/22/2014)... 22, 2014 A new and technologically ... laxity with results that are surprising even the most ... the skin with radio frequency, ThermiTight has been dubbed ... under the skin to “inject” heat to the tissues ... this single treatment solution for skin laxity produces results ...
(Date:7/21/2014)... one of the fastest-growing high school sports in the ... the sometimes hard-hitting game. The growing participation numbers, however, ... risk of injury in lacrosse practice and competition. , ... American Journal of Sports Medicine and available in ... Injury Research and Policy at Nationwide Children,s Hospital and ...
(Date:7/21/2014)... iFitDress.com, a famous company of wedding ... its exclusive collection of 2014 glitter evening dresses ... its brand new gowns. , iFitDress.com is one of ... Its sales boomed in the recent years, not just ... because of the amicable services offered on its website. ...
Breaking Medicine News(10 mins):Health News:High school lacrosse players at risk of concussions other injuries 2Health News:High school lacrosse players at risk of concussions other injuries 3Health News:CareTouch is a Peak Sponsor for the 9th Annual Hike for Hospice in Morrison, Colorado 2Health News:New Minimally Invasive Procedure, ThermiTight, “Injects” Radio Frequency to Treat Skin Laxity 2Health News:New study finds high school lacrosse players at risk for concussions, other injuries 2Health News:New study finds high school lacrosse players at risk for concussions, other injuries 3Health News:iFitDress.com: 2014 Glitter Evening Dresses For Worldwide Clients 2
... Change to Win Executive Director Greg Tarpinian on the ... to prevent employee,misclassification by New York Governor Eliot Spitzer:, ... unions with six million members,in the growth occupations and ... care, from construction and transportation to food,processing and hospitality ...
... program where small changes make a huge impact, ... as we celebrate the end of Healthy Steps, a ... Philadelphia Housing,Authority, and Philadelphia Safe and Sound on Friday, ... Community Center, 2500 Jackson Street in,South Philadelphia., The ...
... Kaiser Permanente has successfully,certified its greenhouse gas ... becoming the first health care organization to,earn the ... now,publicly and voluntarily reporting its 2006 GHG emissions ... paying attention to the organization,s impact on,the environment ...
... from the Centers for Disease Control and Prevention over ... in eight countries that lack the large-scale public health ... of the grant will support the efforts of Tulane ... of Ethiopia and rural Jimma University, to train ...
... Sept. 7 As states consider,proposals to expand ... assesses,the impact of prior efforts in states across ... launched "insurance reforms" with significant,unintended consequences. A number ... a few years of implementation. The study by,Milliman, ...
... N.C., Sept. 7 Pharmaceutical companies,face a unique ... and marketing forces, and quality production processes while ... The case studies in the,Multi-Year Compendium of Pharmaceutical ... were presented by industry leaders at Global,Benchmarking Council ...
Cached Medicine News:Health News:Tarpinian: Misclassification is Theft 2Health News:Tarpinian: Misclassification is Theft 3Health News:On September 7th Local Organizations Partner to Celebrate 'Healthy Steps' 2Health News:Kaiser Permanente Achieves Climate Action Leader Status 2Health News:Tulane University to receive $14M for international HIV/AIDS program 2Health News:New AHIP Report Takes a Ten Year Look at the Unintended Consequences of State Efforts to Change the Insurance Market 2Health News:Multi-Year Compendium of Pharmaceutical Case Studies Available from Best Practices, LLC 2
Each handle is designed to fit a specific trephine size....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Medicine Products: