Navigation Links
AMT Prepares for Submission of Marketing Authorization Dossier for AMT-011 (Glybera(R))
Date:6/12/2008

AMSTERDAM, June 13 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today that it has concluded enrollment and treated the last patient in the pivotal trial for it's lead product AMT-011 (Glybera(R)) for Hyperlipoproteinemia, a seriously debilitating and potentially lethal disease. After recent preparatory meetings with the rapporteur countries Germany and the United Kingdom of the European Medicines Agency (EMEA), AMT expects to file the Marketing Authorization Dossier with EMEA not later than the fourth quarter of 2008.

AMT has developed AMT-011 as a cure for patients with the rare genetic disorder Hyperlipoproteinemia (HPL) type I, also known as LPL-deficiency. These patients have extremely high fat levels in their blood resulting in recurrent and potentially lethal pancreatitis as well as an increased risk of cardiovascular complications and diabetes. Because of a defective gene HPL-patients do not produce an enzyme that normally breaks down fats in the blood. Currently, there is no effective treatment or cure for this seriously debilitating and potentially lethal disease.

AMT-011 is a gene therapy product designed to insert a healthy gene into the patient's body to replace the defective gene. The product is administered by a series of injections into muscle tissue after which the body starts to make the missing enzyme again. The advantage of this therapy is its potential to cure a disease instead of just treating the symptoms. AMT expects to finish the ongoing clinical trial with AMT-011 according to plan.

About Amsterdam Molecular Therapeutics

AMT has a unique gene therapy platform that to date appears to circumvent many if not all of the obstacles that have prevented gene therapy from becoming a mainstay of clinical medicine. Using adeno-associated viral (AAV) vectors as the delivery vehicle of choice for therapeutic genes, the company has been
'/>"/>

SOURCE Amsterdam Molecular Therapeutics B.V
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Columbia University Medical Center and Rosetta Genomics Announce Columbia Universitys Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
2. Synbiotics Corporation Announces Human Submission for FluDetect(R)
3. FDA to Extend Review of Data Quality Submission for Genasense(R) in Melanoma
4. PARIs eFlow Included in Gileads NDA Submission for Aztreonam Lysine for Inhalation
5. BD Announces FDA 510(K) Submission of Rapid Molecular Test to Identify Patients Carrying Staph Superbug Prior to Surgery
6. Indevus Announces Submission of New Drug Application
7. European Regulatory Agency Accepts Cell Therapeutics, Inc.s Marketing Authorization Application for XYOTAX(TM) for Lung Cancer for Review
8. Cell Therapeutics, Inc. (CTI) Submits European Marketing Authorization Application for XYOTAX(TM)
9. Infant Formula Manufacturers Again under Ethical Cloud: Marketing Gimmick Linked to Serious Illnesses
10. Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)
11. ADVENTRX Meets Primary Endpoint in ANX-530 Marketing-Enabling Clinical Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... THOUSAND OAKS, Calif. , May 23, 2013 ... Deutsche Bank 38 th Annual  Healthcare Conference on Thursday, ... Boston , beginning at 9:20 a.m. Eastern Daylight ... Investor Relations at Amgen, will present at the conference. Live ... Calendar on Amgen,s website, www.amgen.com , under Investors. A ...
(Date:5/23/2013)... May 23, 2013 Hearing health affects a man,s ... and remain socially and professionally engaged, he should address any ... message that the Better Hearing Institute (BHI) is ... National Men,s Health Week , which leads up to and ... from June 10 through June 16. To ...
(Date:5/23/2013)... May 23, 2013  TeamHealth Medical Call Center ... and nurse advice lines, announces its newly formed ... nursing and administrative leaders, provides clinical expertise to ... cost-effective services for hospital clients, physician clients and ... system evolves, it,s imperative to continuously advance our ...
Breaking Medicine Technology:Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4TeamHealth Medical Call Center Forms Clinical Advisory Committee 2
... Applied Isotope Technologies (AIT), a company focused on ... and industrial segments by applying its patented-protected technology ... in a 1,500 square foot analytical facility in ... campus on the south side of Pittsburgh at ...
... Va., May 11, 2011 Star Scientific, Inc. (NASDAQ: ... 2011 yesterday with the Securities and Exchange Commission (SEC). ... compared with $149 thousand for the same quarter in ... the Rock Creek Pharmaceuticals subsidiary and in test market ...
Cached Medicine Technology:Applied Isotope Technologies Opens New Facility in PLSG Life Sciences Campus 2Star Scientific Files First Quarter Report, Updates Details of Flint Study Using RCP-006 2Star Scientific Files First Quarter Report, Updates Details of Flint Study Using RCP-006 3Star Scientific Files First Quarter Report, Updates Details of Flint Study Using RCP-006 4
(Date:5/23/2013)... 23, 2013 Vegas Hotel Escapes, ... to announce all new vacation packages for the ... to Las Vegas for this patriotic holiday will ... thanks to VegasHotelEscapes.com's new special pricing available on ... that it guarantees the lowest prices possible on ...
(Date:5/23/2013)... Funeral Financials is encouraging American’s to ... EOD Memorial Foundation Funeral Financials considers EOD’s ... from the war. , According to MarineEOD.com, bomb ... the U.S. was even at war. True EOD’s ... the Explosive Ordnance Disposal Badge. EOD technicians have been ...
(Date:5/23/2013)... (HealthDay News) -- A modified version of the ... tumors, preliminary research suggests. Scientists at Duke ... as PVSRIPO, uses an engineered form of the ... attacks cancer cells. The therapy shows promise in ... aggressive brain tumor, they said. "These early ...
(Date:5/23/2013)... May 23, 2013 “Talk. They Hear ... that empowers parents to talk to children as young ... drinking, was launched today by the Substance Abuse and ... occurred in conjunction with SAMHSA’s 2013 National Prevention Week—an ... action around, substance abuse and mental health issues. , ...
(Date:5/23/2013)... Minn. -- Mayo Clinic researchers have used next generation ... aggressive prostate cancer tumors have similar genetic origins, which ... online today in the journal Cancer Research . ... alterations using next generation sequencing in adjacent Gleason patterns ... with changes in pathology," says ,John Cheville, M.D., Mayo ...
Breaking Medicine News(10 mins):Health News:Funeral Financials Asks Americans to Donate their Memorial Day Beer Money to Help EOD Scholarship 2Health News:Funeral Financials Asks Americans to Donate their Memorial Day Beer Money to Help EOD Scholarship 3Health News:Modified Polio Virus May Help Fight Brain Tumors, Study Suggests 2Health News:New Campaign to Help Parents Talk to Younger Children About the Dangers of Underage Drinking 2Health News:Mayo Clinic genomic analysis lends insight to prostate cancer 2
... WEDNESDAY, Sept. 7 (HealthDay News) -- Introducing powder-free latex gloves ... among workers, a new study shows. Researchers followed more ... for 4.5 years. They tested the amount of latex allergen ... before and after the hospitals switched to powder-free latex gloves. ...
... University] -- Thousands of college football players began competing around ... the new season comes new data on the risks of ... and quarterbacks suffer the hardest hits to the head, while ... The researchers measured head blows during games and practices over ...
... , WEDNESDAY, Sept. 7 (HealthDay News) -- Although it is ... the best time in a person,s life, the risk of ... In the United States, suicide is the second leading ... according to Maureen Dasey-Morales, a psychologist from Wichita State University. ...
... , TUESDAY, Sept. 6 (HealthDay News) -- Contrary to ... breast self-exams are useful for the detection of breast ... mammographies and evaluations of palpable masses are important tools ... of a study to be presented at the 2011 ...
... Women over the age of thirty who test positive for HPV ... cervical cancer screening, according to a study published online TK in ... infection is the main cause of cervical cancer, although most women ... infections in women under the age of 25 go away. Screening ...
... TUESDAY, Sept. 6 (HealthDay News) -- Many first-year medical students ... white and upper social class people, but these biases don,t ... a survey at one medical school. Johns Hopkins School ... students who took part in a Web-based survey that included ...
Cached Medicine News:Health News:Switch to Powder-Free Latex Gloves Cuts Health Workers' Allergy Risk 2Health News:Running backs take hardest hits to the head, linemen take the most 2Health News:Running backs take hardest hits to the head, linemen take the most 3Health News:Teens, College-Age Youth at High Risk of Suicide, Expert Says 2Health News:Annual Breast Exams, Mammograms Still Key to Detecting Breast Cancer 2Health News:Annual Breast Exams, Mammograms Still Key to Detecting Breast Cancer 3Health News:Screening for HPV persistence and cervical cancer risk 2Health News:Patient Care Not Affected by Med Student Biases: Study 2
...
Malis Curette, bayonet, titanium handle, stainless steel shaft, working distance 102 mm, length 203 mm....
Cobb Curettes, reverse angled, 11"....
Castroviejo "HM" Micro Needle Holder with Tungsten-Carbide Inserts, with catch. Serrated....
Medicine Products: