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ALS Therapy Development Institute and Anida Pharma Partner to Investigate Potential Treatments for ALS
Date:9/10/2013

CAMBRIDGE, Mass., Sept. 10, 2013 /PRNewswire-USNewswire/ -- The ALS Therapy Development Institute (ALS TDI) announced today that it has entered into a research partnership with Anida Pharma, Inc., to investigate a potential treatment for ALS, also known as Lou Gehrig's disease.   

(Logo: http://photos.prnewswire.com/prnh/20110204/DC42625LOGO)

Under the terms of the agreement with Anida, ALS TDI will test their lead compound, Neuroprotectin D1 (NPD1), in SOD1 mice for functional benefit.  NPD1, also referred to as Protectin D1 (PD1), activates resolution circuits to control neuroinflammation and prevent cell death, but also has trophic effects. To date, ALS TDI has conducted preclinical proof of concept studies with NPD1 in SOD1 mice. Through these pharmacodynamic studies, ALS TDI has demonstrated that it can deliver pharmacologically active levels of NPD1 to the central nervous system of the SOD1 mice, providing sufficient evidence to move it forward for additional preclinical testing.

"This partnership is yet another example of how our Institute, which is quite literally led by ALS patients and their families, identifies opportunities that otherwise may not get evaluated as a potential treatment for ALS," says Steve Perrin, Ph.D., CEO and CSO of ALS TDI. "It really is about moving as quickly as possible for patients today, and we are committed to doing just that through this partnership with Anida and the more than two dozen other programs our experienced drug development team is simultaneously working on at the Institute."

Anida marks the 12th venture philanthropy investment ALS TDI has made. Since 2007, ALS TDI has made more than $5 million of ventur
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SOURCE ALS Therapy Development Institute
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