Navigation Links
ACD Announces Clinical Study Results Using its RNAscope™ Technology
Date:2/28/2011

SAN ANTONIO, Feb. 28, 2011 /PRNewswire/ -- Advanced Cell Diagnostics, Inc. (ACD) today announced the results of its clinical study utilizing RNAscope™ technology to detect human papillomavirus (HPV) E6/E7 mRNA in routine clinical specimens of head and neck cancer. HPV status determined by the RNAscope™ HPV test was highly predictive of patient outcome and highly concordant with that determined by existing methods. Significantly, the RNAscope™ test under development demonstrated 16% higher detection sensitivity than the HPV DNA test used in the study.

These results will be presented today at the 100th annual meeting of United States & Canadian Academy of Pathology (USCAP 2011). The RNAscope™ HPV test detects E6/E7 mRNA from seven high risk HPV genotypes known to be associated with certain head and neck cancers. The study included 211 head and neck cancers from the oropharynx (base of tongue and throat). It compared the RNAscope™ test with two other tests detecting HPV DNA and the cellular protein p16. RNAscope™ identified 78% of the cases to be positive for HPV, compared to 62% and 79% by the HPV DNA and p16 assays, respectively. HPV-positive tumors as determined by RNAscope™ were associated with 77% lower risk of death following standard therapies (hazard ratio = 0.23, p < 0.001 for overall survival and disease-specific survival), compared to HPV-negative tumors.

"To determine whether a tumor is caused by HPV, it requires more than just detecting the presence or absence of the virus. Detecting transcriptionally active HPV in the tumor cells is critical to establish its presence as clinically significant," said Dr. James Lewis Jr. of Washington University in St. Louis, the principal investigator in this collaborative study. "The RNAscope™ assay uniquely addresses this clinical need by detecting the viral E6/E7 mRNAs and allowing their direct visualization in the tumor cells," continued Dr. Lewis
'/>"/>

SOURCE Advanced Cell Diagnostics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. PDL BioPharma Announces European Patent Office Determination of Validity of PDLs European Patent is Final
2. PDL BioPharma Announces Regular Quarterly Dividend Policy
3. Nile Therapeutics Announces Plans to Pursue a Post-Acute Indication in Heart Failure
4. Tongjitang Chinese Medicines Company Announces Extraordinary General Meeting of Shareholders
5. ConvaTec Announces New Appointment to Leadership Team
6. Verenium Announces Changes in Senior Management
7. Savient Pharmaceuticals Announces U.S. Launch of KRYSTEXXA™; Reports Fourth Quarter and Year-End 2010 Financial Results
8. Sanofi-Aventis Announces Approval and Closing of BMP Sunstone Acquisition Creating a Strong Consumer Health Care Platform in China
9. BrainScope® Announces Appointment of Professor Peter Andrews, MD to Its Medical Advisory Board
10. American Medical Systems Announces U.S. Launch of Conceal™ Low Profile Reservoir for Penile Prosthetics
11. Naviscan® Announces Collaboration With Neoprobe Corporation to Enable Pipeline Technology Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Aug. 29, 2014 Thoratec Corporation (NASDAQ: ... circulatory support therapies to save, support and restore failing ... 2014 Morgan Stanley Global Healthcare Conference on Wednesday, September ... and Chief Executive Officer, will provide an update on ... (9:55 a.m., Pacific Daylight Time).   A ...
(Date:8/29/2014)... Aug. 29, 2014 Research and Markets ... Orthopedic Instrument Industry Report, 2014-2017" report to their ... and rising proportion of reimbursement for medical expenses, the ... with its scale presenting a CAGR of 19.2% during ... three product segments of orthopedic instruments in ...
(Date:8/29/2014)... , Aug. 29, 2014 Research and Markets ... Drug Pipeline Insight 2014" report to their offering. ... US is one of the largest segments of pharmaceuticals industry. ... rate, while the available therapies were unable to meet the ... the market for CNS disorder, especially over the past two ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2US CNS Disorders Drug Pipeline Insight 2014 2
... Scientific Corporation (NYSE: BSX ) announces results ... WATCHMAN® Left Atrial Appendage Closure (LAAC) device.  The data ... by 75 percent in patients with atrial fibrillation who ... Vivek Reddy, M.D., Director of Cardiac Arrhythmia Service at ...
... ECTE ), a company developing its needle-free ... glucose monitoring system and its Prelude® SkinPrep System for ... quarter ended March 31, 2012.  Echo,s Quarterly Report on ... through Echo,s website at www.echotx.com . ...
Cached Medicine Technology:Study of First-in-Class WATCHMAN® Device Shows 75 Percent Reduction in Stroke Risk in Patients with Atrial Fibrillation Not Eligible for Oral Anticoagulation Therapy 2Study of First-in-Class WATCHMAN® Device Shows 75 Percent Reduction in Stroke Risk in Patients with Atrial Fibrillation Not Eligible for Oral Anticoagulation Therapy 3Study of First-in-Class WATCHMAN® Device Shows 75 Percent Reduction in Stroke Risk in Patients with Atrial Fibrillation Not Eligible for Oral Anticoagulation Therapy 4Study of First-in-Class WATCHMAN® Device Shows 75 Percent Reduction in Stroke Risk in Patients with Atrial Fibrillation Not Eligible for Oral Anticoagulation Therapy 5Echo Therapeutics Announces First Quarter 2012 Financial Results 2Echo Therapeutics Announces First Quarter 2012 Financial Results 3Echo Therapeutics Announces First Quarter 2012 Financial Results 4Echo Therapeutics Announces First Quarter 2012 Financial Results 5
(Date:9/1/2014)... September 01, 2014 BCC Research ( ... BLOOD-BRAIN BARRIER TECHNOLOGIES AND GLOBAL MARKETS , the global ... in 2013 and is expected to reach $38.7 million ... $471.5 million by 2019, which is equivalent to 64.9% ... The receptor-mediated transport (RMT) segment is forecasted to grow ...
(Date:9/1/2014)... Top10BestSEOHosting.com has recently compared many web hosting companies. ... is here to announce that JustHost, Bluehost and ... 2014. , JustHost ( http://www.justhost.com/track/seohosts ) provides new ... plan. The company’s approach to hosting is to ... and powerful enough for anyone to use. And ...
(Date:9/1/2014)... 01, 2014 Pastor Thompson is an ordained ... Eagle Village. He is a licensed minister through the Church ... past twenty years in New Mexico, Colorado and North Dakota. ... marriage this year. He also has two beautiful daughters, ... in Pastoral Ministry from Nazarene Bible College, in Colorado Springs ...
(Date:8/31/2014)... 2014 An analysis of 32 studies ... revealed a link between lower levels of Vitamin D ... the August 2014 issue of American Journal ... form of Vitamin D found in blood. , ... D lower than 9 nanograms/milliliter (ng/mL) were twice as ...
(Date:8/31/2014)... GoDaddy, IX Web Hosting and Bluehost are popular ... hosting, which is the method of partitioning a ... which has the appearance and capabilities of running ... compared many professional web hosting suppliers and announced ... hosting suppliers in the global market. , GoDaddy ...
Breaking Medicine News(10 mins):Health News:Global Market for Blood-Brain Barrier (BBB) Technology to Reach $471.5 Million in 2019; Highest CAGR Growth in Latin American Market With 10.5% 2Health News:Global Market for Blood-Brain Barrier (BBB) Technology to Reach $471.5 Million in 2019; Highest CAGR Growth in Latin American Market With 10.5% 3Health News:Why Top10BestSEOHosting.com Calls Them Great Web Hosting Suppliers 2Health News:NutriGold Highlights New Study on the Importance of Vitamin D to Our Life Span 2Health News:NutriGold Highlights New Study on the Importance of Vitamin D to Our Life Span 3Health News:NutriGold Highlights New Study on the Importance of Vitamin D to Our Life Span 4Health News:GoDaddy, IX Web Hosting and Bluehost Are Awarded As Hosting Experts by Top10BestSEOHosting.com 2
... Christine ... Chief Executive Officer, ... Barr Laboratories, Inc., -- In this newly created position, Mundkur has responsibility for ... development, regulatory affairs, operations, quality, and sales and marketing. Under her leadership, ...
... Corporation announces a,call for research papers involving ... device is designed to promote best practice ... of the administration,set when disconnected from the ... of the IV administration line between drug,administrations, ...
... HILL, N.C., March 28 With continuing economic,woes, ... show,return to gain management buy-in. "Use great service ... a downturn," explained a benchmarking,manager in new product ... there is a downturn.", At "Using Quality ...
... Spokesperson,Andrew McDonald said:, "Instead of ... focus on,helping 70,000 UHW-W members win ... better than to have their contracts ... leadership.", For more information, visit ...
... of "Glacial Pace" in Stopping,Post-Claim Rescissions, Failing to ... 27 California,s,Department of Managed Health Care has ... any of 90 cases of illegal rescission found ... a,hearing in the state Senate,s Health Committee., ...
... of Oriental Medicine at Austin in conjunction with the American, ... ... botanical studies., AUSTIN, Texas, March 27 The High Falls ... Great,Barrington, MA, has been awarded a grant from the W.K. Kellogg ...
Cached Medicine News:Health News:Barr Pharmaceuticals, Inc. Executive Bios 2Health News:Barr Pharmaceuticals, Inc. Executive Bios 3Health News:Barr Pharmaceuticals, Inc. Executive Bios 4Health News:Baxa Corporation Launches Call for Research Papers 2Health News:Superior Customer Service Imperative During Economic Downturn 2Health News:Consumer Advocates Call for Governor to Make Good on His Promise to Protect Patients From Illegal Cancellations of Health Insurance 2Health News:Consumer Advocates Call for Governor to Make Good on His Promise to Protect Patients From Illegal Cancellations of Health Insurance 3Health News:Consumer Advocates Call for Governor to Make Good on His Promise to Protect Patients From Illegal Cancellations of Health Insurance 4Health News:Consumer Advocates Call for Governor to Make Good on His Promise to Protect Patients From Illegal Cancellations of Health Insurance 5Health News:Oriental Medicinal Herb Garden Dedication 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: