Navigation Links
ACD Announces Clinical Study Results Using its RNAscope™ Technology
Date:2/28/2011

SAN ANTONIO, Feb. 28, 2011 /PRNewswire/ -- Advanced Cell Diagnostics, Inc. (ACD) today announced the results of its clinical study utilizing RNAscope™ technology to detect human papillomavirus (HPV) E6/E7 mRNA in routine clinical specimens of head and neck cancer. HPV status determined by the RNAscope™ HPV test was highly predictive of patient outcome and highly concordant with that determined by existing methods. Significantly, the RNAscope™ test under development demonstrated 16% higher detection sensitivity than the HPV DNA test used in the study.

These results will be presented today at the 100th annual meeting of United States & Canadian Academy of Pathology (USCAP 2011). The RNAscope™ HPV test detects E6/E7 mRNA from seven high risk HPV genotypes known to be associated with certain head and neck cancers. The study included 211 head and neck cancers from the oropharynx (base of tongue and throat). It compared the RNAscope™ test with two other tests detecting HPV DNA and the cellular protein p16. RNAscope™ identified 78% of the cases to be positive for HPV, compared to 62% and 79% by the HPV DNA and p16 assays, respectively. HPV-positive tumors as determined by RNAscope™ were associated with 77% lower risk of death following standard therapies (hazard ratio = 0.23, p < 0.001 for overall survival and disease-specific survival), compared to HPV-negative tumors.

"To determine whether a tumor is caused by HPV, it requires more than just detecting the presence or absence of the virus. Detecting transcriptionally active HPV in the tumor cells is critical to establish its presence as clinically significant," said Dr. James Lewis Jr. of Washington University in St. Louis, the principal investigator in this collaborative study. "The RNAscope™ assay uniquely addresses this clinical need by detecting the viral E6/E7 mRNAs and allowing their direct visualization in the tumor cells," continued Dr. Lewis
'/>"/>

SOURCE Advanced Cell Diagnostics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. PDL BioPharma Announces European Patent Office Determination of Validity of PDLs European Patent is Final
2. PDL BioPharma Announces Regular Quarterly Dividend Policy
3. Nile Therapeutics Announces Plans to Pursue a Post-Acute Indication in Heart Failure
4. Tongjitang Chinese Medicines Company Announces Extraordinary General Meeting of Shareholders
5. ConvaTec Announces New Appointment to Leadership Team
6. Verenium Announces Changes in Senior Management
7. Savient Pharmaceuticals Announces U.S. Launch of KRYSTEXXA™; Reports Fourth Quarter and Year-End 2010 Financial Results
8. Sanofi-Aventis Announces Approval and Closing of BMP Sunstone Acquisition Creating a Strong Consumer Health Care Platform in China
9. BrainScope® Announces Appointment of Professor Peter Andrews, MD to Its Medical Advisory Board
10. American Medical Systems Announces U.S. Launch of Conceal™ Low Profile Reservoir for Penile Prosthetics
11. Naviscan® Announces Collaboration With Neoprobe Corporation to Enable Pipeline Technology Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... Jan. 23, 2015 A lot of discussion in the ... treating  certain illnesses, injuries, or conditions. As medical science advances, ... methods with ones that they consider to be more cutting ... not one textbook method of treatment that stands out as ...
(Date:1/23/2015)...  The Partnership to Fight Chronic Disease (PFCD) released a public opinion ... a new study analyzing the impact of increased cost sharing on ... working to educate policy makers and the public on the costs ... on how the Iowa healthcare exchange could ...
(Date:1/23/2015)... BETHESDA, Md. , Jan. 23, 2015  Northwest Biotherapeutics, Inc. ... developing DCVax® personalized immune therapies for operable and inoperable solid ... will present at the 7 th Annual Phacilitate Immunotherapy ... NW Bio,s presentation at Phacilitate will take place on January ...
Breaking Medicine Technology:No One-Size-Fits-All Remedy for Hernia Correction 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3
... filed suit today against Johnson & Johnson, Inc. and DePuy ... of the DePuy ASR XL Acetabular Hip Replacement System that ... of John David Hart in Fort Worth, Texas, is the ... United States District Court for the Eastern District of Texas ...
... (Becton, Dickinson and Company) (NYSE: BDX ), ... of its acquisition of Accuri Cytometers, Inc., an Ann ... cytometers for researchers. The acquisition expands BD,s ... and helps expand the use of flow cytometry technology ...
Cached Medicine Technology:DePuy Recalled Hip Device Lawsuit Filed in East Texas 2BD Completes Acquisition of Accuri Cytometers, Inc. 2
(Date:1/22/2015)... 2015 Gabe’s Chemo Duck Program is pleased to ... app ever created for kids with cancer. The Chemo Duck App, ... is filled with enjoyable games to help children of all ages ... app helps to keep kids entertained, educated and at ease while ...
(Date:1/22/2015)... January 22, 2015 Blue Cross and Blue ... who exemplify what it means to “Live Fearless.” ... people to share their stories about how they or someone ... inspired others by living in the moment. By telling these ...
(Date:1/22/2015)... New York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo ... the federal multidistrict litigation underway in U.S. District Court, ... an Order dated January 20th, the Court has remanded ...
(Date:1/22/2015)... York, NY (PRWEB) January 22, 2015 ... College of Sports Medicine flagship journal Medicine & ... with L-Citrulline before exercise may help reduce gastrointestinal ... exercise. 1 , Participants in the double-blind, ...
(Date:1/22/2015)... DC (PRWEB) January 22, 2015 Payday ... in vulnerable communities and cause financial distress to the ... by analysts at Howard University’s Center on Race and ... dollars in economic activity, payday loans at the same ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2
... of vegetables and fruits could be worse than abusing alcohol ... ,It has been estimated that the minimum recommended daily ... vegetables at least. ,According to the 2005 ... accounted for a disability adjusted life years (DALY) rating of ...
... Researchers have confirmed that their studies on bacteria that ... widespread and persistent ear infections// that irritate kids, which ... is pointless. ,Otitis media, a condition of ... to visit doctor and or antibiotic prescriptions in the ...
... science and microbiology and molecular genetics, and his colleagues from ... the ability and potential for growing flu virus. , ... production of new human flu vaccines which is cheaper and ... He identified the new cell line while working on the ...
... are taking part in an initiative to gauge if ... people who have suffered a stroke recently//. The MíTICO ... Isquemic Ictus. ,The study included patients from different ... to three months previously. By means of periodical controls, ...
... is working on four vaccines, including those for treating ... currently working on four vaccines for anthrax, dengue, Japanese ... anthrax vaccine have been completed, which is ready for ... told reporters here today., ,The company would also ...
... wireless device that measures the acidity of stomach contents ... of the nose pain and throat discomfort// associated with ... reflux disease. ,However, while the new technology ... was better for diagnosing or managing these patients, said ...
Cached Medicine News:Health News:‘Biofilms’-Clumped Bacterial Slime Cause Ear Infecti 2Health News:New Cell Lines Cuts Down the Cost and Time in the Production of Flu Vaccine 2Health News:New Reflux Disease Technology More Comfortable, Not More Effective 2Health News:New Reflux Disease Technology More Comfortable, Not More Effective 3
The CdTOX A OIA gets the results you need without specimen extraction or instrumentation. Results are available in minutes vs hours or days for EIA or other methods. The combination of performance, ...
... for Botox therapy and nerve block ... injectable needle has a precisely machined ... with an attached 61-cm (24-in) lead ... insertion. Single patient use only. A ...
... Back Relief Apron has standard ... the weight from the shoulders ... aid of a 6" wide ... strap keeps apron snug. Belts ...
Shielding's Standard Coat Apron with open back allows for freedom of movement, maximum flexibility and increased comfort....
Medicine Products: