Navigation Links
A Window Into Parkinson's Disease
Date:11/12/2008

NEW YORK, Nov. 12 /PRNewswire-USNewswire/ -- A new study being published in this Friday's online edition of Cell will help answer the question, what causes Parkinson's disease?

One of the most pressing questions in the medical research into Parkinson's disease is what causes the sensitive cells in the brain to die in the first place. Answering this question has been especially difficult because there are two nearly identical types of brain cells that produce dopamine and they are mixed together in the same brain regions. However, only one cell type is affected in Parkinson's, the other is spared. Scientists have wanted to compare these closely related brain cells in the hope that differences between the two would explain why the sensitive cells die. This understanding will suggest opportunities for intervention.

The main obstacle has been the infeasibility of separating the two cell types for analysis. Doctors Paul Greengard and Myriam Heiman of The Michael Stern Parkinson's Disease Foundation and their colleagues at The Rockefeller University have developed a system that solves this fundamental technological problem. These scientists have focused on discovering which genes are turned on or off in the two similar cell types. If one views a cell as a computer, then the genes can be viewed as software. Unique programs operate depending on which genes are turned on. When genes are "turned on", they cause the cell to produce specific proteins.

What makes cells vulnerable to Parkinson's disease depends largely on the kinds and amounts of proteins they produce, or their "translational profile."

The new method discovered by Greengard, Heiman, and colleagues, Translating Ribosome Affinity Purification (TRAP), reveals translational profiles in cells by isolating the genetic messages as they pass through the protein production factories called ribosomes.

This new technique will help propel the scientific community, which has struggled
'/>"/>

SOURCE The Michael Stern Parkinson?s Research Foundation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Miami Jewish Home and Hospital, Berma Research Group and Segal Institute for Clinical Research Enrolling Local Patients in Study of Investigational Therapy to Treat Alzheimers Disease
2. Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate for Treatment of Active Celiac Disease
3. Raptor Pharmaceuticals to Collaborate with Centre Hospitalier Universitaire dAngers for Phase II Clinical Trial in Huntingtons Disease
4. VIA Pharmaceuticals Announces Positive Results of Phase 2 Studies of VIA-2291 in Patients With Serious Cardiovascular Disease
5. Physicians Health Study II Finds No Magic Bullet for Preventing Cardiovascular Disease
6. Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinsons Disease Research
7. MedImmune Advances Pediatric Disease Prevention Program With Start of Phase 1/2a Clinical Trial for Respiratory Syncytial Virus Vaccine
8. Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus
9. Novexel to Present Five Posters at the Joint Annual Interscience Conference on Antimicrobial Agents and Chemotherapy and the Infectious Disease Society of America (ICAAC/IDSA) Meeting
10. BioMarin Announces Positive Results From Phase 2A Clinical Study of 6R-BH4 in Sickle Cell Disease
11. Michael J. Fox Foundation Awards $2 Million for Research on Cognitive and Mood Symptoms of Parkinsons Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Norgine B.V. today announced that the Phase ... NER1006, presented at the 79 th Annual Scientific ... Philadelphia, PA , has met its primary ... of cleansing success. The study demonstrated high quality bowel ... screening colonoscopy patients. [1] (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a) ...
(Date:10/19/2014)... Wash. , Oct. 20, 2014 CTI ... that it will report its third quarter 2014 financial ... of the U.S. financial markets. Following the announcement, members ... call to discuss the results and provide a general ... Access to the event can be obtained as follows: ...
(Date:10/18/2014)... , Oct. 18, 2014  In a ... Rights Campaign (HRC), the nation,s largest lesbian, gay, ... endorsed the use of Truvada for Pre-Exposure Prophylaxis ... tool used to prevent the spread of a ... the only brand name anti-HIV drug combination currently ...
Breaking Medicine Technology:Positive Results from Phase II Data Show NER1006 Achieves High Quality Bowel Cleansing Efficacy 2CTI BioPharma to Report Third Quarter 2014 Financial Results on October 29, 2014 2HRC Endorses PrEP, Calls for Bold Action to Expand Access to Anti-HIV Drug 2HRC Endorses PrEP, Calls for Bold Action to Expand Access to Anti-HIV Drug 3
... Milestone Scientific Inc. (OTCQB: MLSS), the recognized leader ... filed its 2010 year-end results for the 12 months ... Exchange Commission on Wednesday, March 30, 2011. ... April 4, 2011 beginning at 4:15 PM Eastern Daylight ...
... UBM Canon and IVD Technology ... The Fundamentals of In Vitro Diagnostics. This one-hour event will ... and will offer an in-depth analysis and discussion from ... With the advent of the sequencing of ...
Cached Medicine Technology:Milestone Scientific Will Host Its 2011 Conference Call on Monday, April 4, 2011 2"IVD Technology" Announces Upcoming Webcast: Omics and the Development of IVDs 2"IVD Technology" Announces Upcoming Webcast: Omics and the Development of IVDs 3
(Date:10/20/2014)... 20, 2014 Punzoné , the first ... U.S., has a lot to celebrate this month. October marks ... the achievements and contributions of Americans of Italian heritage and ... and today it shares its favorite Italian cocktails and encourages ... Italy - even if it is only in a glass. ...
(Date:10/20/2014)... 2014 Do you ever feel difficulty ... a wonderful app Metassessor for teachers, specialists and parents. ... helped its client “Intervention Development LLC” to launch Metassessor ... designed for iOS 4.3 or later and is Compatible ... optimized for iPhone 5. It is now available on ...
(Date:10/19/2014)... The leading review website, Top10BestSEOHosting.com, has ... GreenGeeks are the best Dedicated Server Hosting suppliers. ... want to buy high quality hosting and save ... manager of Top10BestSEOHosting.com says, “We believe that iPage ... everyone. A lot of the global clients enjoy ...
(Date:10/19/2014)... York (PRWEB) October 19, 2014 Dr. ... Population Fund, welcomes news of a ceasefire agreement that ... more than 200 girls who were kidnapped from the ... have languished in captivity long enough, and it is ... and communities," stated Dr. Osotimehin. , "We owe it ...
(Date:10/19/2014)... working in the garment industry for decades, LunaDress’ dress specialists ... one of the company’s top designers, many ladies like prom ... add beauty to them. Chiffon floor length outfits are also ... selection of 2014 long prom dresses. , As a ... in over 20 popular designs. The company intends to meet ...
Breaking Medicine News(10 mins):Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 3Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 4Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 2Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 3Health News:Top10BestSEOHosting.com Considers iPage And GreenGeeks As The Best Dedicated Server Hosting Suppliers 2Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2
... , THURSDAY, Oct. 13 (HealthDay News) --,Smoking ... are genetically susceptible to the mental health disorder, according ... population have the variant of the serotonin gene (5-HTT) ... Radboud University Nijmegen in the Netherlands. They analyzed ...
... CHINA (October 13, 2011) Autism Speaks, the world,s ... largest genomic organization in the world and a global ... to create the world,s largest library of sequenced genomes ... Autism Speaks Autism Genetic Resource Exchange (AGRE), this collaboration ...
... will benefit from a new, pan-Canadian Terry Fox Research ... in which ovarian cancer is diagnosed and managed. ... a total of $5-million in funding for a five-year, ... will identify new biomarkers to predict and treat this ...
... disparities between Latinos and non-Latino whites, mostly from a policy ... perspective of the patient, in terms of access, use and ... how do the physicians feel about the quality of care ... patients, compared with physicians whose patients are primarily white and ...
... Maureen Salamon HealthDay Reporter , WEDNESDAY, Oct. ... esophageal cancer for patients with a condition known as ... once reported, a large new Danish study suggests. ... people, researchers determined that those with Barrett,s esophagus -- ...
... , WEDNESDAY, Oct. 12 (HealthDay News) -- Black Americans ... cancer have worse overall and recurrence-free survival rates than whites, ... nearly 15,000 black and white colorectal cancer surgery patients who ... between 1977 and 2002. All the patients received the same ...
Cached Medicine News:Health News:Autism Speaks and BGI to complete whole genome sequencing on 10,000 with autism 2Health News:Terry Fox Research Institute aims to change diagnosis and management of ovarian cancer worldwide 2Health News:Terry Fox Research Institute aims to change diagnosis and management of ovarian cancer worldwide 3Health News:Physicians treating Latinos have high hurdles to jump, study shows 2Health News:Esophageal Cancer Risk Less Dire for Certain Patients: Study 2Health News:Esophageal Cancer Risk Less Dire for Certain Patients: Study 3Health News:Blacks Fare Worse Than Whites After Colon Cancer Surgery 2
The SZX9 is one of the top research stereo microscopes in the Olympus line. It has the largest zoom range of any of our stereo microscopes....
... and chromatic correction for the focal plane, ... flat images for observation and photomicrography by ... wavelengths up to the near UV range ... types of low autofluorescence makes these objectives ...
Inquire...
This is the most versatile family of objectives. One and the same set of objectives can be used for all common contrasting methods: Brightfield, darkfield, phase contrast, DIC, epi-fluorescence, and ...
Medicine Products: