Navigation Links
"Off-Label" Use of Antipsychotic Drugs for Some Conditions Not Supported By Evidence
Date:9/27/2011

ROCKVILLE, Md., Sept. 27, 2011 /PRNewswire-USNewswire/ -- There is little evidence to support the use of atypical antipsychotic drugs for some treatments other than their officially approved purposes, even though many clinicians continue to commonly prescribe these drugs for so-called "off label" uses, according to a new report from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality (AHRQ). An article based on information in the report will be published in the September 28 issue of the Journal of the American Medical Association.

The report finds that atypical antipsychotic medications—approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia, bipolar disorder and, in some cases, depression—are commonly prescribed to treat other behavioral conditions.

The report, which is an update of a 2007 report, found some evidence to support the off-label use of atypical antipsychotic medications. Evidence was strongest, for example, for the off-label use of risperidone, olanzapine and aripiprazole to treat symptoms of dementia; quetiapine to treat generalized anxiety disorder; and risperidone to treat obsessive-compulsive disorder.

However, evidence was lacking to justify the use of these and other atypical antipsychotic drugs to treat substance abuse problems, eating disorders or insomnia, the report noted. Atypical antipsychotic medications have been linked to some harms, including a small increased risk of death in elderly patients with dementia, according to the report.

The report, a comparative effectiveness review prepared for AHRQ's Effective Health Care Program by the Southern California Evidence-based Practice Center, based at the RAND Corporation, is available at http://www.effectivehealthcare.ahrq.gov.

"While atypical antipsychotic medications are not for everyone, many patien
'/>"/>

SOURCE Agency for Healthcare Research & Quality
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Genetic Variation Associated with Treatment Response in a Clinical Study of a New Atypical Antipsychotic Fiaptatm (iloperidone)
2. AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Generalized Anxiety Disorder - a First for the Atypical Antipsychotic Class of Medicines
3. Forest Laboratories, Inc. and Gedeon Richter Plc Announce Positive Phase II Results with the Investigational Antipsychotic Cariprazine in Patients with Acute Mania Associated with Bipolar I Disorder
4. Generic Erosion of Established Branded Atypical Antipsychotics Will Cause the Schizophrenia Drug Market To Decline More Than $1 Billion by 2013
5. Fred A. Baughman Jr., MD Announces: Vets Deaths Are Not Suicides or Overdoses but Sudden Cardiac Deaths Due to Prescription Antipsychotics and Antidepressants
6. New Company Starts, Bridging the Development Gap in the Discovery of Cancer Drugs
7. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
8. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
9. Study Published in Endocrinology Reports Potential of Modigene Technology to Extend Duration of Protein Drugs
10. Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference
11. Surface Logix Presents Positive Phase 1 Repeat-Dose Trial Data on SLx-4090 at The 16th International Symposium on Drugs Affecting Lipid Metabolism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... Aug. 27, 2015 WuXi PharmaTech (Cayman) Inc. ... technology platform company serving the pharmaceutical, biotechnology, ... process development and manufacturing subsidiary Shanghai SynTheAll ... approval from the Japan PMDA for the ... branded commercial drug in July. STA is ...
(Date:8/27/2015)... CAMBRIDGE, Mass. , Aug. 27, 2015 Oryzon ... & Renshaw 17th Annual Global Investment Conference in ... Hotel, ORYZON will be represented by President and CEO ... Dr. Buesa will present this information on Thursday September ... (2nd Floor).  The company is completing preclinical development of its ...
(Date:8/26/2015)... NEW YORK , Aug. 26, 2015 The ... a CAGR of 7.0% between 2014 and 2019. Although ... Computerized Physician Order Entry market, India ... the forecast period in this regional market. The increasing demand ... government bodies for implementation of these systems in healthcare facilities ...
Breaking Medicine Technology:WuXi PharmaTech's STA Subsidiary Receives First Approval from Japanese Regulatory Authorities 2ORYZON to Present at Rodman & Renshaw 17th Annual Global Investment Conference 2ORYZON to Present at Rodman & Renshaw 17th Annual Global Investment Conference 3ORYZON to Present at Rodman & Renshaw 17th Annual Global Investment Conference 4Asian Computerized Physician Order Entry Market by Product, by Deployment, by Component -Forecast to 2019 2Asian Computerized Physician Order Entry Market by Product, by Deployment, by Component -Forecast to 2019 3
... vitro microbiology and proof of concept in topical ... March 2007 - Arpida Ltd.,(SWX: ARPN) today announced ... against a large panel of,clinical isolates, including those ... of AR-2474 were found,to be highly effective in ...
... Autism Association calls 2006 Pediatrics study fatally,flawed, CHICAGO, ... at a National Autism Association meeting,bolster claims that ... of,autism spectrum disorders. David Ayoub, MD presented data,suggesting ... pervasive developmental disorder (PDD), a form of autism,in ...
Cached Medicine Technology:Arpida adds novel antibiotic AR-2474 to its preclinical pipeline 2Arpida adds novel antibiotic AR-2474 to its preclinical pipeline 3Newly Released Canadian Data Links Vaccines with Pervasive,Developmental Disorder 2
(Date:8/27/2015)... ... August 27, 2015 , ... More destinations and stores are becoming pet-friendly, ... Amica Insurance is sharing some tips to help your whole family travel safely and ... travel with pets each year. Amica is sharing the following tips from the American ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... for quality market research promotion on the Internet. MarketPublishers.com is now authorised ... Commenting on the partnership agreement, Natalie Aster, Assistant Manager at Partners Department, ...
(Date:8/27/2015)... , ... August 27, 2015 , ... ... Hope and Innovation has grown to having twelve offices in three counties, LA, ... hospitals in the Southern California region. Founded by Dr. Richy Agajanian, the ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... firm that helps libraries, publishers and companies leverage key operational, technical, business ... the VIVO Project. Gunter Media Group, Inc., will provide VIVO related services ...
(Date:8/27/2015)... ... ... An inventor from Gibertsville, Pa., knows how knees can get in the way ... trying to sleep," he said, "so I decided that there needs to be a ... KNEE GUARD helps a user get a better sleep by preventing the knees from ...
Breaking Medicine News(10 mins):Health News:Amica Unleashes 5 Tips for Safe Traveling with Pets 2Health News:Market Publishers Ltd and Black Swan Analysis Sign Partnership Agreement 2Health News:Market Publishers Ltd and Black Swan Analysis Sign Partnership Agreement 3Health News:California’s Largest Private Oncology Practice Serves 50,000 Patients in 8 years 2Health News:DuraSpace Selects Gunter Media Group, Inc. as a Registered Service Provider for VIVO 2Health News:DuraSpace Selects Gunter Media Group, Inc. as a Registered Service Provider for VIVO 3
... University Medical School in Durham, North Carolina and colleagues have ... pain. Patients who use religion or spirituality to cope with ... and boost their sense of well being, the researchers say. ... with chronic illness or chronic pain might find it difficult ...
... liver can injure the donor, it is now established without doubt ... to a person needing it. And the good news is that ... part of his/her liver. ,Donation of a piece of the ... new procedure. It is increasingly being performed in the West where ...
... research-cum-manufacturing agreement between Chiron Corp, the US-based vaccine major, ... potential AIDS vaccine to halt the spread of the ... stage of finalisation. ,Two Hyderabad-based biotechnology/pharma companies -- ... front-runners for the proposed project, which entails an upfront ...
... of the American Association of Endodontists in New Orleans, Louisiana, ... terse message, the dentists said that all toothache need not ... because it may be the early warning for more important ... hygiene has never received its due importance from the masses. ...
... the British government says that smoking will turn out to ... the threat of even HIV. The British broadcasting corporation reported ... more people than any other disease in the next 20 ... in Sussex, United Kingdom, says smoking and other tobacco related ...
... up to 3 million lives a year. WHO released a ... March. The report says most of those who die are ... the developing world are particularly at risk for water-borne diseases. ... contaminated water and 90% of those deaths are among children ...
Cached Medicine News:Health News:Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos 2
... and Cronin, Inc. is ... Patient Footwear, Orthopedic Softgoods, ... Products. Our products are ... and available in the ...
... and Cronin, Inc. is ... Patient Footwear, Orthopedic Softgoods, ... Products. Our products are ... and available in the ...
... The Blue Line UNO Splint fits small, medium, ... cushioned two-part design includes both dorsal and volar ... extension. Recommended for those experiencing symptoms of Carpal ... for busy clinics - stock one splint to ...
Comfort Wrist Immobilizer with thumb abduction. 8"L, soft, padded comfort-type wrist immobilizer with dorsal metal stay. The thumb is held in abduction and splintered with a short metal stay....
Medicine Products: