Navigation Links
Total PSA IRMA Test

ProductsTotal PSA IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item Total PSA IRMA Test
Features 
  • Requires only 50 L sample to test
  • No sample pretreatment required
  • Incubation is 2 hrs + 1 hr on shaker at RT
  • Description Prostate-Specific Antigen (PSA) derives its name from its first known site of origin, the prostate gland. The majority of PSA circulates bound to anti-chymotrypsin (PSA-ACT) and other compounds. Serum concentrations of PSA are elevated in patients with prostate cancer, benign prostatic hypertrophy (BPH) and prostatitis [1-3]. In addition, PSA serum levels appear to correlate with the volume and clinical stage of prostate cancer [1,4]. Selective determination of the various forms of PSA (i.e. free PSA, PSA-ACT complex and total PSA) may be useful to distinguish BPH from untreated prostate cancer. The ratio of free PSA to PSA-ACT is lower in untreated prostate cancer patients than in normal individuals or in patients with BPH. Thus, in patients with PSA in the 4 to 10 mg/L range (diagnostic gray zone), determination of free PSA fractions as a percentage of the total levels (i.e. the free PSA percentage) has been proposed as a means to improve discrimination between BPH and untreated prostate cancer in patients [1,3,5,6].

    It has been found that PSA is not specific to the prostate. There are a number of non-prostatic sources of PSA, such as the periurethral glands, breast cancer tissues, breast fluids, amniotic fluid and other [7]. Urinary PSA has also been measured in women with hyperandrogenic syndromes such as polycystic ovarian syndrome [8].

    1. Vessella RL. Clin Chem 39:2035, 1993.
    2. Papsidero LD, et al. Cancer Res 40:2428, 1980.
    3. Kuriyama M, et al. Cancer Res 40:4658, 1980.
    4. Graves HCB. Clin Chem 38:1930, 1992.
    5. Lilja H, et al. Clin Chem 37:1618, 1991.
    6. Stenman UH, et al. Cancer Res 51:222, 1991.
    7. Diamandis EP & Yu H. Urol Clin North Am 24:275-282, 1997.
    8. Obiezu CV et al. J Clin Endocrinol Metab 86:1558-1561, 2001.
    Info Diagnostic Systems Laboratories, Inc.
    Customer Service: (800) 231-7970
    Web site: http://www.dslabs.com

    Related medicine products :

    1. Laserex Tango M (Total Mobile Version)
    2. Bilirubin, Direct & Total
    3. Bilirubin Total Reagent
    4. Total Bilirubin Reagent
    5. Total Protein
    6. Total Protein Reagent
    7. Total Protein Reagent Set
    8. Iron Total (TIBC)
    9. Iron (Total/Ferene)
    10. Cholesterol, Total
    11. Total Internal Reflection Fluorescence Microscopy
    REFRESH TEARS® lubricating eye drops does more than just smoothe and relieve dry, irritated eyes. REFRESH TEARS® creates a shield of protection against further irritation with its unique, lon...
    ... REFRESH ENDURA™ is the first ... benefit all 3 layers of ... of moisture that lubricates and ... eyes). This helps seal in ...
    ALPHAGAN® (brimonidine tartrate ophthalmic solution) 0.2% is indicated for lowering IOP in patients with open-angle galucoma or ocular hypertension....
    ... solution is a prescription eye drop ... to use after your cataract surgery. ... may cause them to become inflamed. ... inflammation include redness and swelling. If ...
    Medicine Products:
    (Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... that was developed to enhance the health of felines. The formula is all-natural and ... main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are ...
    (Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
    (Date:6/25/2016)... CA (PRWEB) , ... June 25, 2016 , ... As ... with Magna Cum Laude and his M.D from the David Geffen School of Medicine ... and returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive ...
    (Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June 14 ... The article goes on to state that individuals are now more comfortable seeking to ... operations such as calf and cheek reduction. The Los Angeles area medical group, Beverly ...
    (Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association (PHA) ... will receive two significant new grants to support its work to advance research ... anniversary by recognizing patients, medical professionals and scientists for their work in fighting ...
    Breaking Medicine News(10 mins):
    (Date:6/24/2016)... , June 24, 2016  Collagen Matrix, ... design, development and manufacturing of collagen and mineral ... announced today that Bill Messer has ... Marketing to further leverage the growing portfolio of ... devices. Bill joins the Collagen Matrix ...
    (Date:6/24/2016)... -- The Academy of Managed Care Pharmacy (AMCP) today ... allow biopharmaceutical companies to more easily share health care ... coverage decisions, a move that addresses the growing need ... The recommendations address restrictions in the sharing of product ... a prohibition that hinders decision makers from accessing HCEI ...
    (Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
    Breaking Medicine Technology: