Navigation Links
Total PSA IRMA Test

ProductsTotal PSA IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item Total PSA IRMA Test
Features 
  • Requires only 50 L sample to test
  • No sample pretreatment required
  • Incubation is 2 hrs + 1 hr on shaker at RT
  • Description Prostate-Specific Antigen (PSA) derives its name from its first known site of origin, the prostate gland. The majority of PSA circulates bound to anti-chymotrypsin (PSA-ACT) and other compounds. Serum concentrations of PSA are elevated in patients with prostate cancer, benign prostatic hypertrophy (BPH) and prostatitis [1-3]. In addition, PSA serum levels appear to correlate with the volume and clinical stage of prostate cancer [1,4]. Selective determination of the various forms of PSA (i.e. free PSA, PSA-ACT complex and total PSA) may be useful to distinguish BPH from untreated prostate cancer. The ratio of free PSA to PSA-ACT is lower in untreated prostate cancer patients than in normal individuals or in patients with BPH. Thus, in patients with PSA in the 4 to 10 mg/L range (diagnostic gray zone), determination of free PSA fractions as a percentage of the total levels (i.e. the free PSA percentage) has been proposed as a means to improve discrimination between BPH and untreated prostate cancer in patients [1,3,5,6].

    It has been found that PSA is not specific to the prostate. There are a number of non-prostatic sources of PSA, such as the periurethral glands, breast cancer tissues, breast fluids, amniotic fluid and other [7]. Urinary PSA has also been measured in women with hyperandrogenic syndromes such as polycystic ovarian syndrome [8].

    1. Vessella RL. Clin Chem 39:2035, 1993.
    2. Papsidero LD, et al. Cancer Res 40:2428, 1980.
    3. Kuriyama M, et al. Cancer Res 40:4658, 1980.
    4. Graves HCB. Clin Chem 38:1930, 1992.
    5. Lilja H, et al. Clin Chem 37:1618, 1991.
    6. Stenman UH, et al. Cancer Res 51:222, 1991.
    7. Diamandis EP & Yu H. Urol Clin North Am 24:275-282, 1997.
    8. Obiezu CV et al. J Clin Endocrinol Metab 86:1558-1561, 2001.
    Info Diagnostic Systems Laboratories, Inc.
    Customer Service: (800) 231-7970
    Web site: http://www.dslabs.com

    Related medicine products :

    1. Laserex Tango M (Total Mobile Version)
    2. Bilirubin, Direct & Total
    3. Bilirubin Total Reagent
    4. Total Bilirubin Reagent
    5. Total Protein
    6. Total Protein Reagent
    7. Total Protein Reagent Set
    8. Iron Total (TIBC)
    9. Iron (Total/Ferene)
    10. Cholesterol, Total
    11. Total Internal Reflection Fluorescence Microscopy
    ... Low Binding 20l Barrier Tips. Low binding technology ... proteins bound to the tip. Most other filter ... the focus is on liquid not adhering to ... low binding which reduces the binding of valuable ...
    Ideal for use with low volume samples on the Biomek robotic pipetting systems, the ART 20R provides guaranteed protection for your expensive workstation....
    Hydrophobic PE filter without self-sealing additives, permits sample recovery after accidental over-pipetting. All filters are sterile (to USP, DAB, Ph.Eur. standards) and PCR clean (free from human ...
    ... tips eliminate false signals and contamination ... tested, Promega Barrier Tips offer performance ... nucleic acids (PCR(a)), radioactive isotopes, tissue ... serological specimens. , ,Promega Barrier Tips ...
    Medicine Products:
    (Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
    (Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
    (Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
    (Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
    (Date:6/24/2016)... York, NY (PRWEB) , ... June 24, 2016 ... ... publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as a ... that “the most beautiful women in the world, and the most handsome men, ...
    Breaking Medicine News(10 mins):
    (Date:6/23/2016)... , June 23, 2016 Research ... MEMS Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data ... analysis. Assessment of major trends with potential impact on the ... analysis of market segmentation which comprises of sub markets, regional ...
    (Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
    (Date:6/23/2016)...  Guerbet announced today that it has been named ... . One of 12 suppliers to receive ... support of Premier members through exceptional local customer service ... to lower costs. ... outstanding customer service from Premier," says Massimo Carrara ...
    Breaking Medicine Technology: