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Testosterone RIA Test

ProductsTestosterone RIA Test
Company Diagnostic Systems Laboratories, Inc.
Item Testosterone RIA Test
Features 
Description Testosterone, (17-Hydroxy-4-androstene-3-one), a C19 steroid, is one of the most potent naturally secreted androgens [1]. In postpubertal males, testosterone is secreted primarily by the testes with only a small amount derived from peripheral conversion of androstenedione [2]. In adult women, it has been estimated that over 50% of serum testosterone is derived from peripheral conversion of androstenedione secreted by the adrenal and ovary, with the remainder from direct secretion of testosterone by these glands [2,3]. The majority of circulating testosterone is bound by SHBG and a smaller portion is bound by albumin. Only 1-2% exists in circulation as unbound or free testosterone [4].

In males, testosterone, either directly or after conversion to DHT, normally functions in fetal Wolffian duct differentiation, development of male external genetalia, stimulation of spermatogenesis, stimulation of anabolic activity in a variety of tissues and, possibly, behavioral and psychological effects [5,6]. In both sexes, testosterone contributes to the development of secondary sexual hair, acne, and scalp hair patterns. In prepubertal males, elevated testosterone levels are found in precocious puberty [7] and in androgen receptor defects [5]. In adult males, low testosterone levels are associated with various pathological conditions, including primary hypogonadism. In females of all ages, elevated testosterone levels can be associated with a variety of virilizing conditions, including adrenal tumors and polycystic ovarian disease [3].

  1. Dorfman RI & Shipley RA. Androgens. JohnWiley and Sons, Inc., New York, 1956, pp. 116-128.
  2. Horton E & Tait JF. J clin Invest 45:301-313, 1966.
  3. Pang S & Riddick L. Hirsutism. IN Lifshitz F (ed). Pediatric Endocronology, A Clinical Guide, second edition. Marcel Dekker, Inc., New York, 1990, pp. 259-291.
  4. Cumming DC & Wall SR. J. Cin Endocrinol Metab 61: 873-876, 1985.
  5. Griffin JE & Wilson JD, The androgen resistance syndroms: 5alpha-reductase deficiency, testicular feminization, and related syndromes. IN: Scriver CR, et al. (eds.): The Metabolic Basis of Inherited Disease, 6th ed. McGraw-Hill, New York, 1989, pp. 1919-1944
  6. Wilson JD. Endocrin Rev 9:181-199,1988.
  7. Holland FJ. Endocrinol Metab Clin North Am 64: 191-210, 1991
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

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Titanium. Thin jaws provide secure grasp of the folded lens for insertion into the eye. Reverse action forceps with angled shaft....
... Facilitates grasping and implanting the haptic ... within the capsular bag without wrist ... long jaws are placed in the ... Smooth, flat, cross action handle with ...
2.5 mm cups angled 50 degrees, 10 mm from angle to tip. Serrated handle with polished finish....
2.5 mm cups angled 50 degrees, 10 mm from angle to tip. Serrated cross action handle with polished finish....
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