|Products||Testosterone RIA Test|
|Company||Diagnostic Systems Laboratories, Inc.|
|Item||Testosterone RIA Test|
|Description|| Testosterone, (17-Hydroxy-4-androstene-3-one), a C19 steroid, is one of the most potent naturally secreted androgens . In postpubertal males, testosterone is secreted primarily by the testes with only a small amount derived from peripheral conversion of androstenedione . In adult women, it has been estimated that over 50% of serum testosterone is derived from peripheral conversion of androstenedione secreted by the adrenal and ovary, with the remainder from direct secretion of testosterone by these glands [2,3]. The majority of circulating testosterone is bound by SHBG and a smaller portion is bound by albumin. Only 1-2% exists in circulation as unbound or free testosterone .
In males, testosterone, either directly or after conversion to DHT, normally functions in fetal Wolffian duct differentiation, development of male external genetalia, stimulation of spermatogenesis, stimulation of anabolic activity in a variety of tissues and, possibly, behavioral and psychological effects [5,6]. In both sexes, testosterone contributes to the development of secondary sexual hair, acne, and scalp hair patterns. In prepubertal males, elevated testosterone levels are found in precocious puberty  and in androgen receptor defects . In adult males, low testosterone levels are associated with various pathological conditions, including primary hypogonadism. In females of all ages, elevated testosterone levels can be associated with a variety of virilizing conditions, including adrenal tumors and polycystic ovarian disease .
|Info|| Diagnostic Systems Laboratories, Inc.|
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Web site: http://www.dslabs.com