Navigation Links
TSH IRMA Test

ProductsTSH IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item TSH IRMA Test
Features 
Description Thyroid-stimulating hormone (TSH) is a 32 kDa glycoprotein secreted by the thyrotrope cells of the anterior pituitary gland [1]. The structure of human TSH is similar to that of the pituitary and placental gonadotropins, consisting of an a-subunit which is similar or identical between these hormones and a unique beta-subunit, which confers hormonal specificity. TSH stimulates production of thyroid hormones by binding to thyrocyte membrane receptors, leading to stimulation of cAMP-dependent iodine transport and resultant thyroid hormone synthesis [2]. TSH secretion is stimulated by thyrotropin-releasing hormone (TRH) which is secreted by the hypothalamus and is regulated at both the pituitary and hypothalamic levels by thyroid hormones. Low levels of thyroid hormones lead to increased TSH secretion and elevated thyroid hormone levels lead to decreased TSH secretion.

During human fetal life, serum TSH levels are measurable at about 18 weeks gestation and increase to a peak at the beginning of the 3rd trimester. At birth, a sharp and dramatic increase in serum TSH levels occurs with a subsequent rapid decline over several hours [3]. Postnatal secretion of TSH is relatively age- and sex-independent and occurs in a circadian pattern with a nadir in the late afternoon and a peak at approximately midnight. Measurement of serum TSH levels have been used in the diagnostic evaluation and therapeutic monitoring of primary hypo- and hyper-thyroidism. In addition, measurement of TSH levels following parenteral administration of TRH has been used in the evaluation of TSH-deficiency [4].

  1. Magner JA. Endocrin Rev 11:354-385, 1990.
  2. Vassart G & Dumont JE. Endocrin Rev 13:596-611, 1992.
  3. Fisher DA & Klein AH. N Engl J Med 304: 702-712, 1981.
  4. Alsever RN & Gotlin RW. Handbook of Endocrine Tests in Adults and Children, second edition. Year Book Medical Pub, Chicago, 1978, pp 22-25.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Laserex Tango M (Total Mobile Version)
2. Bilirubin, Direct & Total
3. Bilirubin Total Reagent
4. Total Bilirubin Reagent
5. Total Protein
6. Total Protein Reagent
7. Total Protein Reagent Set
8. Iron Total (TIBC)
9. Iron (Total/Ferene)
10. Cholesterol, Total
11. Total Internal Reflection Fluorescence Microscopy
For Frontalis Suspension in patients with significant ptosis and poor levator function....
Bioceramic orbital implants insert easily into orbital socket and will not cling to surrounding tissue. Improved interconnectivity between pores enhances vascularization. Implants may be easily drill...
...
... based on SIREMOBIL Iso-C, the first truly ... intra-operative 3D-Mode, the 3D-dataset is immediately available ... movement. This allows the surgeon to perform ... the procedure. This 3D capability is especially ...
Medicine Products:
(Date:5/26/2016)... ... 26, 2016 , ... On May 23rd during the National Eye Institute’s “Healthy ... water advocate, was honored by Ashram, Inc. as the world’s foremost water visionary. , ... the banks of the Nile to fill their red clay pots with life-sustaining water.” ...
(Date:5/26/2016)... , ... May 26, 2016 , ... The introduction of ... ADDING PROTECTION TO YOUR HEAD ™”. , “We are proud to introduce ... the football front we have Brian Quick, wide receiver for Los Angeles who was ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... . With over 20 years of experience in leading technology and human resources ... years of university teaching, Morrow-Fox will be featured on Metcalf’s VoiceAmerica radio ...
(Date:5/26/2016)... ... , ... May 2016 – Lips may be a central feature on our ... numbers of clients now ask about lip plumping and primping techniques and want tips ... Advanced Dermatology P.C. , The trend is a national one, with 2.4 ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... is happy to announce the launch of its brand equity product, Brandvantage. ... to reflect the dynamic landscape of modern consumer decision-making. The proprietary framework ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... -- Joe Marziani has joined VMS BioMarketing as senior vice president of sales, announced ... role, Marziani will lead the company,s business development and sales team, exploring new opportunities ... Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
(Date:5/24/2016)... 24, 2016 ... , la première endoprothèse à double thérapie ... l,intervention portant sur les membres inférieurs et ... OrbusNeich, entreprise mondiale spécialisée dans la fourniture ... vie, a élargi son portefeuille pour inclure ...
(Date:5/24/2016)... , May 24, 2016 Een ... verbindt, zodat zij collectief patiënten kunnen behandelen, hun kennis ... het idee achter de nieuwe en revolutionaire MDLinking App, ... de Nederlandse vaatchirurg dr. Hans Flu en oncologisch chirurg ... die inmiddels beschikbaar is, wordt op dinsdag 24 mei ...
Breaking Medicine Technology: