Navigation Links
TSH IRMA Test

ProductsTSH IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item TSH IRMA Test
Features 
Description Thyroid-stimulating hormone (TSH) is a 32 kDa glycoprotein secreted by the thyrotrope cells of the anterior pituitary gland [1]. The structure of human TSH is similar to that of the pituitary and placental gonadotropins, consisting of an a-subunit which is similar or identical between these hormones and a unique beta-subunit, which confers hormonal specificity. TSH stimulates production of thyroid hormones by binding to thyrocyte membrane receptors, leading to stimulation of cAMP-dependent iodine transport and resultant thyroid hormone synthesis [2]. TSH secretion is stimulated by thyrotropin-releasing hormone (TRH) which is secreted by the hypothalamus and is regulated at both the pituitary and hypothalamic levels by thyroid hormones. Low levels of thyroid hormones lead to increased TSH secretion and elevated thyroid hormone levels lead to decreased TSH secretion.

During human fetal life, serum TSH levels are measurable at about 18 weeks gestation and increase to a peak at the beginning of the 3rd trimester. At birth, a sharp and dramatic increase in serum TSH levels occurs with a subsequent rapid decline over several hours [3]. Postnatal secretion of TSH is relatively age- and sex-independent and occurs in a circadian pattern with a nadir in the late afternoon and a peak at approximately midnight. Measurement of serum TSH levels have been used in the diagnostic evaluation and therapeutic monitoring of primary hypo- and hyper-thyroidism. In addition, measurement of TSH levels following parenteral administration of TRH has been used in the evaluation of TSH-deficiency [4].

  1. Magner JA. Endocrin Rev 11:354-385, 1990.
  2. Vassart G & Dumont JE. Endocrin Rev 13:596-611, 1992.
  3. Fisher DA & Klein AH. N Engl J Med 304: 702-712, 1981.
  4. Alsever RN & Gotlin RW. Handbook of Endocrine Tests in Adults and Children, second edition. Year Book Medical Pub, Chicago, 1978, pp 22-25.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Laserex Tango M (Total Mobile Version)
2. Bilirubin, Direct & Total
3. Bilirubin Total Reagent
4. Total Bilirubin Reagent
5. Total Protein
6. Total Protein Reagent
7. Total Protein Reagent Set
8. Iron Total (TIBC)
9. Iron (Total/Ferene)
10. Cholesterol, Total
11. Total Internal Reflection Fluorescence Microscopy
... Patient safety in the operating and recovery ... cost-effective solution for combined haemodynamic and airway ... and post anesthesia care units. The Cardiocap ... all providing the basic haemodynamic measurements. Two ...
... picture of patient respiration and ventilation., ,The ... respiration and ventilation monitors available. The Capnomac Ultima ... allows you to measure the essential airway gas ... and N 2 O easily and reliability. The ...
Adhesive discs sold on rolls of 100, 250, or 1000 each. Manufactured from non-latex medical grade adhesives & material. One size fits all chest pieces....
For accurately monitoring core temperature and heart and breath sounds as well as for gastric suctioning....
Medicine Products:
(Date:8/16/2017)... ... ... Maury Regional Health has announced a large-scale adoption of AccuVein vein visualization ... Regional Medical Center is making vein visualization part of their standard of care. , ... importantly, helps our staff members locate a vein that will provide good access to ...
(Date:8/16/2017)... ... August 16, 2017 , ... A global leader in the treatment ... clinics in all 29 Indian states—bringing the country one step closer to eliminating clubfoot ... the nonprofit organization is on track to enroll 10,000 children in the clubfoot treatment ...
(Date:8/16/2017)... ... , ... Fusion Flix Inc., a Telly Award Winning, Non Profit Corporation has ... viewers in a partnership with the Amazon Video Direct Streaming Distribution Platform. , Their ... Ray disc in 2018. Proceeds will be going to further health research. , ...
(Date:8/16/2017)... (PRWEB) , ... August 16, 2017 , ... TopConsumerReviews.com recently ... Lab Testing . , The healthcare industry in the United States has undergone ... are the days of needing to have a doctor’s order to get a blood ...
(Date:8/16/2017)... , ... August 16, 2017 , ... First Choice ... States, named Dr. Douglas J. Harrison, as the new Medical Director of its Sienna ... new facility Medical Director of our Sienna Plantation location,” said Dr. Michael (Derek) Caraway, ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... , Aug. 15, 2017  AOTI Inc. announced today that its ... Inc., has recently opened a New York City Office in ... of its unique Topical Wound Oxygen (TWO 2 ) homecare therapy. ... Accreditation Commission for Health Care (ACHC) under the company,s DMEPOS accreditation ... ...
(Date:8/8/2017)... Israel, Aug. 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), ... today reports its financial results for the second quarter ... during the second quarter 2017 and to date: ... clinical development programs for the Company,s lead project, BL-8040: ... pivotal study with BL-8040 as novel stem cell mobilization ...
(Date:8/7/2017)... Mich. , Aug. 7, 2017 Diplomat Pharmacy, ... of Joel Saban as president, effective Aug. 7, ... Urick has decided to pursue other interests and will ... "During his tenure, Paul has served us in multiple leadership ... Specialty Pharmacy in Jun. 2015 and has provided decisive, strategic ...
Breaking Medicine Technology: