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Prolactin IRMA Test

ProductsProlactin IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item Prolactin IRMA Test
Description Prolactin is a polypeptide hormone secreted in significant amounts by the anterior pituitary gland and the placenta. Prolactin, in synergy with estrogen, plays an important physiologic role in the initiation and maintenance of mammary gland growth and lactation in humans [1,2]. In addition, prolactin may have effects on cell growth in other tissues and on immune function. Prolactin may also have inhibitory effects on gonadal function when present in high concentrations.

Prolactin is present in several body fluids, including blood plasma, amniotic fluid, milk, mucosal secretions and cerebrospinal fluid. Elevations in plasma prolactin concentrations occur during ovulation, pregnancy, nursing and stress [1-4]. Abnormal elevations in plasma prolactin levels (hyperprolactinemia) can occur as a result of pituitary adenomas, other anatomic and traumatic abnormalities, in response to certain pharmacologic agents and in hypothyroidism. Hypoprolactinemia (low prolactin levels) are observed in cases of hypopituitarism.

  1. Lambert SWJ & MacLeod RM. Physiol Rev 70:219-318, 1990.
  2. Nicoll CS, et al. Endocrin Rev 7:169-203, 1986.
  3. Sinha YN. Endocrin Rev 16:354-369, 1995.
  4. Liu MY & Zhou S. Prog Physiol Sci 21:36, 1990.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
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