Navigation Links
Osteocalcin IRMA Test

ProductsOsteocalcin IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item Osteocalcin IRMA Test
Features Inquire
Description Osteocalcin, also known as bone Gla protein, is a vitamin K-dependent, calcium binding protein which is a major component of the noncollagenous bone matrix [1,2,3]. Osteocalcin is synthesized by osteoblasts in bone, with a small amount produced by odontoblasts in dentin, and hypertrophic chondrocytes [1]. During bone formation, newly synthesized osteocalcin is incorporated into the extracellular bone matrix and a small fraction is released into circulation. Because serum osteocalcin originates exclusively from bone, serum osteocalcin levels reflect bone formation activity [1]. Osteocalcin is also released into serum from the bone matrix during osteoblastic bone resorption. However, this circulates as non-immunoreactive fragments that are rapidly metabolized in the kidney and, to a lesser extent, in the liver [5]. Serum osteocalcin is elevated in disease states characterized by increased bone turnover such as renal osteodystrophy, osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency [1]. Serum osteocalcin measurements are also useful in osteoporosis research, and have shown good correlation with bone histomorphometric measurements [6] and for studying the effects of treatments that modulate bone formation activity [7]. Serum osteocalcin measurements have also been useful in the research of toxic effects on bone [6,8].

  1. Gundberg CM. J Clin Ligand Assay 21:128-138, 1998.
  2. Price PA, et al. Proc Natl Acad Sci USA 73:3374-3375, 1976.
  3. Gallop PM, et al. New Engl J Med 302:1460, 1980.
  4. Price PA, et al. J Biol Chem 256:12760, 1981.
  5. Farrugia W & Melik RA. Calcif Tissue Int 39:234, 1986.
  6. Bikle DD. Am J Med 103:427-436, 1997.
  7. Castracane VD et al. J Bone Min Res 12:S500, 1997.
  8. Kido T et al. Arch Environ Hlth 46:43-49, 1991.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Osteocalcin ELISA Test
2. Osteocalcin by Electrochemiluminescent Immunoassay
Latex agglutination slide test for the qualitative and semi-qualitative detection of antinuclear antibodies to aid in the diagnosis of systemic lupus erthyematosus....
Color-enhanced slide test for the rapid qualitative and semi-quantitative detection of antibodies to streptococcal extracellular antigens in serum, plasma and peripheral blood....
Latex agglutination slide test to aid in the identification of Staphylococcus aureus colonies from culture media....
Hemagglutination slide test for the qualitative and quantitative detection of Rheumatoid Factor in serum or synovial fluid....
Medicine Products:
(Date:4/21/2015)... Optimity Advisors ( Optimity), ... that helps clients in complex industries navigate rapid ... Association of Community Affiliated Plans (ACAP) ... 58 local, not-for-profit, community-affiliated Safety Net Health Plans ... primarily enrolled in public or state-sponsored coverage programs, ...
(Date:4/21/2015)... 2015 When a bandage sticks to ... In order to solve this problem two inventors from ... This improved bandage helps a cut, burn, abrasion or ... enhances air exposure. The bandage is easy to use, ... design was submitted to the St. Louis office of ...
(Date:4/21/2015)... April 21, 2015 NOVAtime Technology, ... enterprise Time and Attendance / Workforce Management solutions, ... from the American Payroll Association (APA) as well ... The APA has been the nation’s payroll authority ... networking opportunities, and recertification credits. Held at the ...
(Date:4/21/2015)... DC (PRWEB) April 21, 2015 ... announce the launch of Medicare-Medicaid Dual Eligibles Database, ... focuses on care provided to the more than ... who account for more than $300 billion in ... researchers – the same team that also creates ...
(Date:4/21/2015)... 2015 One of the most difficult ... meal food cravings. Many diets end badly due to ... meals. Some attempt to eat more often throughout the ... more regular intervals. While this approach does work for ... directly after a meal. For those who are having ...
Breaking Medicine News(10 mins):Health News:Optimity Advisors Named Preferred Vendor by the Association of Community Affiliated Plans (ACAP) 2Health News:NOVAtime Participates in 2015 APA Congress and NetSuite SuiteWorld Conferences in May 2Health News:NOVAtime Participates in 2015 APA Congress and NetSuite SuiteWorld Conferences in May 3Health News:New AIS Database Tracks All Programs, Plans Serving the Dual-Eligible Community 2Health News:Diet Doc Introduces New Neuro Balance, A Proprietary Diet Aid to Help Dieters Eliminate Food Cravings 2Health News:Diet Doc Introduces New Neuro Balance, A Proprietary Diet Aid to Help Dieters Eliminate Food Cravings 3
... Md., May 7 Vaccinogen Inc. said Dutch health,authorities ... immediately clearing the path to more than $100 million ... company,s facility based in Emmen, The,Netherlands also paves the ... -- the final step before the vaccine can be ...
... Holdings Corp. (Nasdaq:,HMSY) today announced that it will present ... be held May 13-15, 2008 at the Four,Seasons in ... Walter Hosp, Chief Financial,Officer of HMS Holdings Corp., will ... HMS Holdings Corp. (Nasdaq: HMSY ) is the ...
... technology will enable physicians to have secure access to, online patient ... ... telephones, MANCHESTER, N.H., May 7 New Hampshire physicians ... Anthem patients, virtually anywhere they can receive an internet,signal, thanks to an ...
... U.S. Department,of Health and Human Services published an update ... Tobacco Use and Dependence,which contains revised and improved recommendations ... smokers in quitting. The,guideline also confirms that there has ... right now., With the release of these new ...
... May 7 /PRNewswire-USNewswire/ - The International,Academy of Compounding ... doctors in applauding the introduction of H. Con. ... and Drug Administration,s,(FDA) new policy restricting women,s access ... interest" and calling on the FDA to,"reverse its ...
... Pa., May 7 Select Medical Corporation,will release the ... on Thursday, May 15, 2008., The Company will ... Wednesday, May 21, 2008, at 11:00am EDT. The domestic ... dial in number is,1-210-839-8503. The passcode for the call ...
Cached Medicine News:Health News:Dutch Authorize Manufacture of Vaccinogen's New Cancer Vaccine; License Clears Path to European Production, Final FDA Trial 2Health News:Anthem Blue Cross and Blue Shield in New Hampshire Announces Unique Enhancement to its ePrescribing Program 2Health News:Anthem Blue Cross and Blue Shield in New Hampshire Announces Unique Enhancement to its ePrescribing Program 3Health News:New Smoking Cessation Guideline Confirms That Now is the Time to Quit Smoking 2Health News:Patients, Doctors, Pharmacists Praise Bipartisan House Resolution on Compounded Hormones Containing Estriol 2Health News:Patients, Doctors, Pharmacists Praise Bipartisan House Resolution on Compounded Hormones Containing Estriol 3
(Date:4/20/2015)... KUALA LUMPUR, Malaysia , April 20, 2015 /PRNewswire/ ... 2015, resulting in a scarcity of opportunities for generic ... drug manufacturers in the region are looking beyond the ... the quality of existing drugs. Certain established generic manufacturers ... research and development of new molecules, although the impact ...
(Date:4/20/2015)... Dr. Gregory Taylor , Canada,s Chief ... after spending a week in West Africa . ... needs on the ground as global efforts continue to reach zero ... prevention efforts in Sierra Leone and ... first-hand the work being done and hear from those on the ...
(Date:4/20/2015)... 20, 2015 Actavis plc (NYSE: ... Mayr , Chief Communications Officer, will retire from ...  In conjunction with Mayr,s retirement, Alex Kelly ... of Chief Communications Officer, effective immediately. Prior to ... Vice President, Chief Communications Officer, Public Affairs and ...
Breaking Medicine Technology:Generic Drug Companies in Asia Focus More on Market Expansion and Quality, Less on Patent Cliff, Finds Frost & Sullivan 2Generic Drug Companies in Asia Focus More on Market Expansion and Quality, Less on Patent Cliff, Finds Frost & Sullivan 3Generic Drug Companies in Asia Focus More on Market Expansion and Quality, Less on Patent Cliff, Finds Frost & Sullivan 4Generic Drug Companies in Asia Focus More on Market Expansion and Quality, Less on Patent Cliff, Finds Frost & Sullivan 5Canada's Efforts Making a Difference in the Fight Against Ebola 2Canada's Efforts Making a Difference in the Fight Against Ebola 3Canada's Efforts Making a Difference in the Fight Against Ebola 4Canada's Efforts Making a Difference in the Fight Against Ebola 5Actavis Announces Retirement of Charles M. Mayr 2Actavis Announces Retirement of Charles M. Mayr 3