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Intact hCG IRMA Test

ProductsIntact hCG IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item Intact hCG IRMA Test
  • Sensitivity: 0.5 mIU/mL
  • Incubation: 30 mins + 30 mins on shaker at RT
  • Shelf Life: 8 wks
  • Description Human chorionic gonadotropin (hCG) is a two chain (alpha- and beta-subunits) glycoprotein hormone secreted by the chorionic tissue of the placenta and is normally found in urine and blood during pregnancy. Produced by the trophoblastic epithelium of the placenta, hCG acts to maintain the corpus luteum in the early stages of pregnancy. The primary utility of hCG measurement is for the early detection and monitoring of pregnancy, and pregnancy related disorders [1,2,3]. Healthy, non-pregnant individuals have low (5 IU/L) to undetectable hCG concentrations in serum. During pregnancy, hCG concentrations increase to about 50 IU/L in the first week after conception and double every 1.5 to 3 days for the first six weeks. Levels continue to rise until the end of the first trimester, then gradually fall to a lower level for the remainder of the pregnancy. After delivery, hCG returns to 5 IU/L and is usually undetectable several days postpartum [4,5,6].

    1. Frances R & Batzer MD. Fertil. Steril. 34: 1-13, 1980.
    2. Sokolove PJ & Faix JD. J. Clin. Immunoassay 14: 196-199, 1991.
    3. Krieg AG: Pregnancy test and evaluation of placental function. IN Henry J.B. (ed.): Clinical Diagnostics, management of laboratory methods, 16th edition. W.B. Sanders Co., Philadelphia, PA, 1979.
    4. Vaitukaitis JL. Recent Progress in Hormone Research 32: 289, 1976.
    5. Braustein GD, et al. Amer. J. Obstet. Gynecol. 126: 678-681, 1976.
    6. Lenton EG, et al. Fertil. Steril. 37: 773-778, 1982.
    Info Diagnostic Systems Laboratories, Inc.
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