Navigation Links
IGFBP-4 ELISA Test

ProductsIGFBP-4 ELISA Test
Company Diagnostic Systems Laboratories, Inc.
Item IGFBP-4 ELISA Test
Features Inquire
Description Insulin-like growth factor binding protein 4 (IGFBP-4) is a 24 kDa protein which specifically binds and modulates the actions of IGF-I and IGF-II. It is also present in a glycoslyated form with a molecular weight of 28 kDa. IGFBP-4 has been identified in all biological fluids, as well as in numerous cell types, including fibroblasts, neuroblastoma, prostate and bone cells [1,2]. IGFBP-4 appears to be inhibitory to IGF action by binding the IGFs and preventing their interaction with the IGF receptors [1]. This inhibitory function of IGFBP-4 is protease dependent [2]. The regulatory mechanisms that control IGFBP-4 expression are still poorly understood, however in bone IGFBP-4 appears to be regulated by PTH and 1,25 dihydroxyvitamin D3 [2]. Serum levels of IGFBP-4 appear to increase with age. In elderly women, this increase appears to be due in part to the age-related increase in PTH production of which is stimulated in calcium deficiency states [3].

  1. Cohen P & Rosenfeld RG. Current Opinion in Pediatrics. 6: 462-467, 1994
  2. Collett-Solberg PF & Cohen P. The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action IN Rosenfield RL (ed) Growth and Growth Disorders. WB Saunders Company, Philadelphia, vol. 25, no. 3, pp 591-614, 1996
  3. Rajaram S, et al. Endocrine Reviews. 18(6): 801-831, 1997
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Microplate ELISA Washers - Manual Microplate Washer
2. Microplate ELISA Washers - Automated Microplate Washer
3. Vitamin D 25-Hydroxy ELISA 026-AC-57F1 Bone and Mineral Metabolism
4. RELISA ANA Screening System
5. BioCheck hCG ELISA
6. Human Chorionic Gonadotropin (HCG) ELISA Kit
7. Human PSA ELISA Kit
8. Total PSA ELISA Test
9. Free PSA ELISA
10. PAP Microwell ELISA
11. Trinity Biotech Captia™ B. burgdorferi IgG/IgM ELISA
Used for retrograde pyelogram. The tip configuration occludes the ureteral orifice and stabilizes the catheter by temporarily wedging in the orifice. Supplied sterile in peel-open packages. Intended ...
... for the injection of contrast medium, anesthetic ... lumen design eliminates the need for multiple ... promote atraumatic passage into and through the ... hydrophilic polymer that when activated, attracts and ...
Used for drainage and retrograde pyelogram. Supplied sterile in peel-open packages. Intended for one-time use....
... The whistle tip has two ... plastic and the Luer fitting adapter ... for identification of left or right. ... sterile and x-ray opaque. The length ...
Medicine Products:
(Date:3/29/2017)... Mt. Horeb, WI (PRWEB) , ... March 29, 2017 , ... ... her patients on early orthodontic treatment and accepting new pediatric patients, with or without ... can help young patients have a better orthodontic outcome and experience. When patients receive ...
(Date:3/29/2017)... ... March 29, 2017 , ... ... oral braces. "The rubber bands used in conjunction with my braces always rubbed ... to design a way to prevent this problem." The O.B.S. was the result ...
(Date:3/29/2017)... PA (PRWEB) , ... March ... ... eastern suburbs and South Hills of Pittsburgh now have easier access to ... Pennsylvania only by Allegheny Health Network (AHN). Orthopaedic surgeons at Forbes Hospital ...
(Date:3/28/2017)... ... March 28, 2017 , ... A ... to improve teacher quality, the field must first improve teacher preparation program design. ... to the next” and that decades of input- and outcome-based research has failed ...
(Date:3/28/2017)... ... 2017 , ... Resoundant, Inc., the developer of Magnetic ... annual customer education symposium, a world-class learning conference that offers educational content designed ... 31, 2017 at the Atlanta Marriott Marquis in Atlanta, Georgia. , Innovations for ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... , March 29, 2017 Global intravenous (IV) iron ... billion by 2021, growing at a CAGR of 5%. ... by a doctor to treat anemia or other iron deficiencies. ... in the body. However, in some cases, oral administrations are ... and intravenous (IV) iron therapy comes into the picture. ...
(Date:3/29/2017)... March 29, 2017 Today, CVS Health officials (NYSE: ... Reynolds , Department of Public Health Director Gerd Clabaugh ... Lukan in announcing the availability of the opioid overdose-reversal ... in Iowa.  CVS Health has established a standing order with ... Pharmacy to expand access to the medication in the state.   ...
(Date:3/29/2017)... Calif. , March 29, 2017  Experts ... recognized remote monitoring devices like  Soberlink Systems  as ... The consensus paper, published in early 2017, concluded ... and valuable in managing patient recovery." ... the Journal of Addiction Medicine, detail a range ...
Breaking Medicine Technology: