Navigation Links
IGFBP-3 ELISA Test

ProductsIGFBP-3 ELISA Test
Company Diagnostic Systems Laboratories, Inc.
Item IGFBP-3 ELISA Test
Features 
Description Human Insulin-like growth factor binding protein-3 (IGFBP-3) is the main binding protein for IGF-I and IGF-II in postnatal serum, as a component of the ~150 kDa ternary complex. This complex consists of IGFBP-3, a molecule of IGF-I or IGF-II and ALS, allowing IGFBP-3, along with ALS, to regulate the actions of the IGFs. The molar concentration of IGFBP-3 in normal serum is proportional to the molar concentration of total IGFs (i.e. IGF-I + IGF-II) [1]. In addition, total IGF levels show higher correlation with GH in circulation than either IGF-I or IGF-II levels alone [2]. IGFBP-3 is GH-dependent, however IGFBP-3 may be less age-dependent than IGF-I [3]. These aspects of IGFBP-3 physiology allow its measurement to reflect GH activity. Thus, in GH deficiency of either pituitary or hypothalamic origin, IGFBP-3 levels are uniformly low. Blum et al. [3] reported that 128/132 children with GH deficiency had serum IGFBP-3 concentrations below the 5th percentile for age. In situations of GH receptor deficiency, such as Laron syndrome, anti-GH antibodies, liver disease or malnutrition, IGFBP-3 levels are also reduced, even in the presence of elevated serum GH concentrations [4]. Measurement of IGFBP-3 levels in serum is a useful diagnostic test for the clinical evaluation of GH-related disorders.

  1. Baxter R & Martin J. J Clin Invest 78:1504-12, 1986.
  2. Powell DR, et al. J Clin Endocrinol Metab 63:1186-1192, 1986.
  3. Blum WF, et al. J Clin Endocrinol Metab 70:1292-8, 1990.
  4. Guevara-Aguirre J, et al. J Clin Endocrinol Metab 76: 417-423, 1993.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. IMMULITE/IMMULITE 1000 IGFBP-3
2. IMMULITE 2000 IGFBP-3
3. IGFBP-3
4. IGFBP-3 IRMA Test
5. Microplate ELISA Washers - Manual Microplate Washer
6. Microplate ELISA Washers - Automated Microplate Washer
7. Vitamin D 25-Hydroxy ELISA 026-AC-57F1 Bone and Mineral Metabolism
8. RELISA ANA Screening System
9. BioCheck hCG ELISA
10. Human Chorionic Gonadotropin (HCG) ELISA Kit
11. Human PSA ELISA Kit
2 mm wide x 3 mm long, with rounded triangular tip. Angled 45 degrees. Hexagonal handle....
5.5 pointed curved blade. Octagonal handle....
3 mm curved blade. Round handle....
8 mm downcutting Royce blade. Angled shaft. 60 mm from angle to tip....
Medicine Products:
(Date:7/23/2014)... (July 23, 2014) Statins, a class of drugs ... patient,s risk of developing Barrett,s esophagus, according to a ... , the official journal of the American Gastroenterological Association. ... with statin use. , "Patients who received statins had ... Barrett,s esophagus compared to non-users," said study author Hashem ...
(Date:7/23/2014)... With cloud storage fast replacing traditional ... LeaseQ announced that that despite the lack of ... still see robust growth in computer hardware and ... technology equipment leasing, visit:, https://www.leaseq.com/computer-equipment-leasing , ... quoted as saying, “Although the growth of server ...
(Date:7/23/2014)... Hill, FL (PRWEB) July 23, 2014 The ... percent reduction in prescription drug deaths from 2010 to 2012. ... infamous for its minimal monitoring of access to some of ... the wrong hands. Florida’s law enforcement launched an initiative ... now nearly nonexistent compared to the 65 that existed in ...
(Date:7/23/2014)... 23, 2014 On July 21, 2014, My ... advocate Jack Tracey for an episode that spoke about the ... Deierlein asks Tracey to talk some about the formation of ... its mission, it was started right here in Charleston, originally ... was to help survivors of sexual abuse. Their purpose has ...
(Date:7/23/2014)... Five years ago, when the SSM St. ... options for babies diagnosed with a medical condition before birth. ... country for innovative fetal therapies. Since then, nearly 1,000 families ... for their babies in the womb, and the team has ... “A number of the babies we see are facing life-threatening ...
Breaking Medicine News(10 mins):Health News:Statin use decreases the risk of Barrett's esophagus 2Health News:LeaseQ Announces That Although Software Investment Remains Sluggish, Technology Equipment Leasing Demand Remains Robust 2Health News:LeaseQ Announces That Although Software Investment Remains Sluggish, Technology Equipment Leasing Demand Remains Robust 3Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 2Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 3Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 4Health News:My Positive Perspective Airs Episode to Raise Attention to the Group Darkness to Light 2Health News:St. Louis Fetal Care Institute Marks Five Years of Life Changing Care and Fetal Surgery 2
... flu at the weekend, taking the death toll in the country ... said Monday . ,Indonesia has seen its toll from ... confirmed human deaths occurred here. ,"A boy who died ... positively infected," Ningrum, from the ministry's National Bird Flu Information Centre, ...
... Dengue fever killed 30 people in Myanmar in the first six ... latest country in the region to experience a surge in ... ministry official, told the weekly Myanmar Times newspaper that the number ... of this year there have been about 3,000 cases of the ...
... milk into a skin-care product that would wipe away wrinkles ... ,The government's team of camel researchers, which has already ... has found cosmetic properties in the hardy mammal's milk. ... to a hospital's skin department to study it on 20 ...
... demonstrated conclusively that a specific protein and its signaling ... essential to the creation and repair of the brains ... mouse models points the way to developing treatments or ... repair in children and adults. The paper will be ...
... make real breakthroughs in childrens medicine if they include children ... ,Professor John Warner was speaking today at the opening of ... to paediatric clinical research. ,The unit is run ... and it is based next to the hospitals paediatric wards ...
... Biology Laboratory (EMBL) and the University of Michigan have ... kidney disease ,In the current online ... the gene cause nephronopthisis (NPHP) in humans and mice. ... childhood that leads to kidney failure requiring organ transplantation. ...
Cached Medicine News:Health News:Indonesia Confirms 81st Bird Flu Death 2Health News:Specific Protein is Instrumental in Myelination 2Health News:Specific Protein is Instrumental in Myelination 3Health News:Experts Need to Include Children in Research 2Health News:New Therapies for Kidney Diseases 2
(Date:7/23/2014)... -- Lightlake Therapeutics Inc. ("Lightlake") (OTCQB: LLTP), a biopharmaceutical ... in opioid antagonists, announced today that it has ... respect to its naloxone-based opioid overdose reversal nasal ... received an additional commitment from the National Institute ... Institutes of Health ("NIH"), to fund a second ...
(Date:7/23/2014)... July 23, 2014 This September leading clinicians ... Las Vegas for DOCtalk 2014 ... author, forward thinker and private practitioner Dr. David ... to candidly discuss clinical and practice management efficiency and ... a unique opportunity to welcome fresh thinking and join ...
(Date:7/23/2014)... 23, 2014 Global healthcare company ... facing currency headwinds, increased price competition and supply disruptions ... Andrew Witty points out that the company is very ... reason to be confident about long-term prospects as well ... CFO Simon Dingemans adds that ...
Breaking Medicine Technology:Lightlake Therapeutics Inc. Files Investigational New Drug Application For Naloxone Nasal Spray For Reversing Opioid Overdose And Announces A Further Collaboration With The National Institute On Drug Abuse 2Lightlake Therapeutics Inc. Files Investigational New Drug Application For Naloxone Nasal Spray For Reversing Opioid Overdose And Announces A Further Collaboration With The National Institute On Drug Abuse 32014 DOCtalk Registration Now Open 22014 DOCtalk Registration Now Open 3