Navigation Links
I-PTH IRMA Test

ProductsI-PTH IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item I-PTH IRMA Test
Features 
Description Parathyroid hormone (PTH) is synthesized by the parathyroid glands [1,2] and secreted in response to decreased extracellular calcium concentrations. PTH prevents hypocalcemia by enhancing bone resorption and decreasing calcium excretion by the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal (residues 35-84) and 2 mid molecule fragments (residues 44-68 and 35-64). The N-terminal fragment retains full biological potency, and is also rapidly degraded in the blood. The biologically inactive C-terminal and mid-molecule fragments are present in the circulation for a much longer period of time, resulting in C-terminal and Mid-Molecule concentrations which are approximately 5 to 10-fold higher than Intact or N-terminal PTH concentrations.

PTH acts directly on bone and kidney and indirectly on the intestine to alter calcium and phosphate concentrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparathyroid hypercalcemia [3,4]. Additionally, PTH is helpful for assessing parathyroid function in renal failure and is often used for dialysis patients.

  1. Endres DB, et al. Endocrinol Metab Clin North Am 18:611-629, 1989.
  2. Orloff JJ, et al. Endocrin Rev 10:476-195, 1989.
  3. Marcus R. Endocrinol Metab Clin North Am 18:647-658, 1989.
  4. Fitzpatrick LA & Bilezikian JP. Am J Med 82:275-282, 1987.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. I-PTH ELISA Test
GP8 is a powerful 3-liter large capacity ventilated benchtop centrifuge which is flexible and easy to use. Performs separations 50-100% faster than the rest, powerful, accomodating and convinient....
Sealed Aero-Lok technology centrifuge. AeroLok technology, a brush less permanently lubricated motor, sturdy aluminum cabinet is covered with a durable, baked-on powder coating in an attractive tan c...
... has an uniquely designed direct ... in which tubes are filled, ... same carrying tray. Spin cycle ... quiet operation, automatic electric brake, ...
... Mobile space saver, very powerful, high ... analog controls, large bright digital display, ... pendulum system), guard barrier, dual lid ... motor, tough steel casing with chemical-resistant, ...
Medicine Products:
(Date:10/17/2018)... ... 2018 , ... The Jacobs & Cushman San Diego Food Bank’s CEO, James ... meeting of its Board of Directors. , California Association of Food Banks (CAFB) ... provides its member food banks with a range of support services, direct service programs ...
(Date:10/16/2018)... ... October 16, 2018 , ... With a petition (case ... of Graves McLain PLLC joins a series of lawsuits filed in states around the ... occurring at Massage Envy locations by Massage Envy’s massage therapists. , This lawsuit ...
(Date:10/16/2018)... ... October 16, 2018 , ... Sheba Vine, JD, CPCO, ... employment law, writes frequently on employment law matters and has contributed articles to ... the Health Care Compliance Professional's Manual titled “Navigating the Evolving Marijuana Landscape” to ...
(Date:10/13/2018)... ... ... At HEI Health, we believe tomorrow’s healthcare can be made affordable today. HEI ... Fall Summit by Marcus Evans. HEI will be hosting an exclusive round table session ... healthcare providers. , Marcus Evans National Healthcare CXO Summit is the premium forum ...
(Date:10/11/2018)... ... October 11, 2018 , ... ... the acquisition of J.Lodge, an industry leader in contact center monitoring and quality ... of a debilitating medical condition—J. Lodge supports alternative work environments and flexible schedules, ...
Breaking Medicine News(10 mins):
(Date:10/16/2018)... ... October 16, 2018 , ... With suicide as the tenth leading cause ... American Psychiatric Nurses Association (APNA) has released a new training to equip nurses working ... by suicide in hospital settings are preventable, a recent survey of 15,000 health and ...
(Date:10/16/2018)... ... October 16, 2018 , ... The iaedp™ Foundation, recognized for ... healthcare treatment providers who treat the full spectrum of eating disorder problems, will ... 12-hour track at Symposium 2019. The courses are regularly offered in a ...
(Date:10/13/2018)... ... October 12, 2018 , ... In the aftermath of ... and has hotel availability for anyone in need, and the Pensacola International Airport ... Florida. In the aftermath, Pensacola is open and has hotel availability for anyone ...
Breaking Medicine Technology: