Navigation Links
I-PTH IRMA Test

ProductsI-PTH IRMA Test
Company Diagnostic Systems Laboratories, Inc.
Item I-PTH IRMA Test
Features 
Description Parathyroid hormone (PTH) is synthesized by the parathyroid glands [1,2] and secreted in response to decreased extracellular calcium concentrations. PTH prevents hypocalcemia by enhancing bone resorption and decreasing calcium excretion by the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal (residues 35-84) and 2 mid molecule fragments (residues 44-68 and 35-64). The N-terminal fragment retains full biological potency, and is also rapidly degraded in the blood. The biologically inactive C-terminal and mid-molecule fragments are present in the circulation for a much longer period of time, resulting in C-terminal and Mid-Molecule concentrations which are approximately 5 to 10-fold higher than Intact or N-terminal PTH concentrations.

PTH acts directly on bone and kidney and indirectly on the intestine to alter calcium and phosphate concentrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparathyroid hypercalcemia [3,4]. Additionally, PTH is helpful for assessing parathyroid function in renal failure and is often used for dialysis patients.

  1. Endres DB, et al. Endocrinol Metab Clin North Am 18:611-629, 1989.
  2. Orloff JJ, et al. Endocrin Rev 10:476-195, 1989.
  3. Marcus R. Endocrinol Metab Clin North Am 18:647-658, 1989.
  4. Fitzpatrick LA & Bilezikian JP. Am J Med 82:275-282, 1987.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. I-PTH ELISA Test
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products:
(Date:8/16/2017)... ... August 16, 2017 , ... Richard Strawn’s new book ... time of a cancer diagnosis, surgery and recovery, the Psalms provided encouragement and ... ways God shows love to those who are sick., Surgical Psalms contains 36 ...
(Date:8/16/2017)... ... 16, 2017 , ... The Visiting Nurse Association (VNA) ... train as hospice volunteers. Volunteers provide much needed joy, support and assistance to ... agency has trained volunteers to be vital members of the interdisciplinary hospice care ...
(Date:8/16/2017)... ... , ... Rollon Skin Care Ltd., one of ... the launch of two new skincare products, Prache Antiaging Cream and Prache Antiaging ... surgery or in-patient cosmetic dermatological procedures. , “Prache Antiaging Cream and Prache Antiaging ...
(Date:8/16/2017)... ... ... “Faith, Through The Eyes of A Child” is the creation of published author, Pauline DiBenedetto. ... at her. Since she was in such great pain, my mother thought that her time ... well. It wasn’t until I was about eight years old, when I had a vision ...
(Date:8/15/2017)... ... August 15, 2017 , ... The first study to ... multiple myeloma has been completed, with the team’s findings now published online ahead of ... , Director of the Blood and Marrow Transplant Program at Roswell Park Cancer Institute, ...
Breaking Medicine News(10 mins):
(Date:8/11/2017)... , Aug. 11, 2017 DarioHealth Corp. (NASDAQ: ... health and big data solutions, today announced that it ... August 14 and host a conference call at 9:00am ... operating and financial results and its strategy and outlook ... hosted by Erez Raphael , Chief Executive Officer, ...
(Date:8/8/2017)... 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage biopharmaceutical ... financial results for the second quarter ended June 30, ... quarter 2017 and to date: ... for the Company,s lead project, BL-8040: ... BL-8040 as novel stem cell mobilization treatment for autologous ...
(Date:8/7/2017)... , Aug. 7, 2017 Insightin Health, ... acquisition, retention, and engagement, announced the selection of ... and Product Development, effective as of February 2017. In ... technology implementation strategy for our clients. Wood brings ... in consulting and business analytics within the healthcare ...
Breaking Medicine Technology: