Navigation Links
Ghrelin, Total ELISA Test

ProductsGhrelin, Total ELISA Test
Company Diagnostic Systems Laboratories, Inc.
Item Ghrelin, Total ELISA Test
Features 
Description Ghrelin is a 28 amino-acid lipophilic peptide with a labile octanoic acid side chain at the serine residue three, that is primarily expressed in specialized enterochromaffin cells located mainly in the mucosa of the fundus of the stomach (1) and has metabolic effects opposite to those of leptin. Ghrelin stimulates food intake, enhances the use of carbohydrates and reduces fat utilization, increases gastric motility and acid secretion, and reduces locomotor activity.

While Ghrelin has potent growth hormone releasing properties comparable to growth hormone releasing hormone (1), it also has powerful growth hormone independent effects (2). Administration of Ghrelin peripherally or centrally into the cerebral ventricles induces weight gain in rodents (3) and in humans, Ghrelin levels peak prior to each meal and then fall to lower levels immediately upon feeding.

In humans, circulating Ghrelin levels are decreased in acute states of positive energy balance and in chronic obesity, but elevated during fasting and in anorexia nervosa. These data further support the hypothesis that the secretion of Ghrelin not only has effects opposite to leptin, but is also regulated antipodal to leptin. Whether increased Ghrelin levels in anorexia nervosa reflect a pathophysiological state of Ghrelin resistance analogous to that of leptin resistance in obesity remains to be elucidated. In addiction, the development of a Ghrelin antagonist, or the development of a mechanism to inhibit Ghrelin release to control appetite may be an important pharmaceutical development for the management of obesity.

Finally, recent evidence suggests that Ghrelin may play a role in reproductive function, a scenario that is analogous to the elucidation of a role of leptin in the control of reproductive function (4).

  1. Kojima M, et al. Nature 402: 656-660, 1999.
  2. Nakazato M, et al. Nature. 409: 194-198, 2001.
  3. Wren AM, et al. Endocrinology 141: 4325-4328, 2000.
  4. Henson, M.C. & Castracane, V.D., eds. (2003) Leptin and Reproduction. Kluwer Academic Publishers, New York, New York.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Laserex Tango M (Total Mobile Version)
2. Bilirubin, Direct & Total
3. Bilirubin Total Reagent
4. Total Bilirubin Reagent
5. Total Protein
6. Total Protein Reagent
7. Total Protein Reagent Set
8. Iron Total (TIBC)
9. Iron (Total/Ferene)
10. Cholesterol, Total
11. Total Internal Reflection Fluorescence Microscopy
Diareader ELX800G...
Plate Reader is an eight channel photometer for the sequential and simultaneous reading of micro-plate strips with 96 wells. High technology, user friendly, powerful and reliable....
... certified microstrip reader. Stat fax 303 ... to use with step-by-step prompting and ... other programming enhancements. On-board software calculates ... & a variety of cutoff options. ...
Iems Incubator/Shaker expansion module for 2 module incubator/shaker. high performance microplate incubator and orbital shaker. It's superior temperature control and efficient orbital shaking reduce ...
Medicine Products:
(Date:9/3/2015)... (PRWEB) , ... September 03, 2015 , ... ... robust distribution channels and efficient customer and technical support services to promote LodonalTM ... approved 90-day Bridging trial evaluating the efficacy and safety of the product. , ...
(Date:9/2/2015)... ... September 03, 2015 , ... Leah Binder, MA, MGA, ... influential leaders in healthcare, will offer the keynote address at the upcoming meeting ... 2015, in Palm Harbor, Florida, at the Innisbrook Resort and Golf Club. For ...
(Date:9/2/2015)... Washington, DC (PRWEB) , ... September 03, 2015 ... ... stacks of nominations to determine who among America’s policymakers, public servants, activists, corporate ... on the nation’s health care. This year, that process led the magazine to ...
(Date:9/2/2015)... (PRWEB) , ... September 02, ... ... the 2015 Warrior-Family Symposium (WFS), cosponsored by the Military Officers Association of ... During the event, "Our Nation's Military: Caring For Our Own,” expert panelists ...
(Date:9/2/2015)... Los Angeles, CA (PRWEB) , ... September 02, 2015 , ... ... working to expand their fleet of truly superb luxury vehicles based on which of ... are pleased to announce the latest step forward in pursuit of this goal: a ...
Breaking Medicine News(10 mins):Health News:Fidson Partners US Firms on New Product Marketing 2Health News:Fidson Partners US Firms on New Product Marketing 3Health News:Fidson Partners US Firms on New Product Marketing 4Health News:ACO Coalition Meeting to Feature Leapfrog’s Leah Binder 2Health News:ACO Coalition Meeting to Feature Leapfrog’s Leah Binder 3Health News:NLN CEO Dr. Beverly Malone Named One of 100 Most Influential in Health Care 2Health News:NLN CEO Dr. Beverly Malone Named One of 100 Most Influential in Health Care 3Health News:MOAA and WWP host 2015 Warrior-Family Symposium Chairman of the Senate Committee on Veterans' Affairs and the Secretary of Veterans Affairs to Speak 2Health News:MOAA and WWP host 2015 Warrior-Family Symposium Chairman of the Senate Committee on Veterans' Affairs and the Secretary of Veterans Affairs to Speak 3Health News:Luxury Line Auto Rental Announces Addition of the Rolls Royce Wraith to their Luxury Fleet 2
... with demand. Two experts in this weeks BMJ debate whether ... there is evidence to the contrary is the answer. ... support organ donation, yet only 23% have registered their wish ... at the British Medical Association. ,Research indicates that ...
... robotic technology may improve survival rates for prostate ... Thomas Jefferson University Hospitals multidisciplinary Genitourinary (GU) cancer ... 21, 2007 at the annual American Urological Society ... that performing a laparoscopic radical prostatectomy (LRP) with ...
... 10-fold over the past 40 years in England, owing to ... finds research published ahead of print in the British ... wide geographical variation in rates suggest that the NHS is ... and training, say the authors. ,The research team ...
... Researchers at Jefferson Medical College have shown that capsule ... small bowel Crohns disease in children. The technology has ... more than five years to diagnose unexplained abdominal bleeding ... is not much bigger than a vitamin pill and ...
... In a move to improve global public health, Weill ... heart disease drug onto the World Health Organization's ... guideline for developing countries to choose which high-priority drugs ... ,Students from Weill Cornell's chapter of Universities Allied for ...
... young to speak or crawl, but they can certainly tell ... with only visual cues. ,Researcher Whitney Weikum ... able to discern when a different language is spoken by ... face movements. ,The findings suggest that babies growing ...
Cached Medicine News:Health News:Is Presumed Consent the Answer to Organ Shortages? 2Health News:Robotic Surgery May Improve Survival Rate For Prostate Cancer Patients 2Health News:NHS Oversupplied With Cataract Surgery, Say Doctors 2Health News:Medical College Students Help Change Global Health Policy 2Health News:Even at Four Months, Babies can Tell When Speakers Switch Languages 2
(Date:9/2/2015)... NEW YORK , Sept. 2, 2015 /PRNewswire/ ... devices are artificial implants used to replace, augment, ... used in a wide range of applications including ... These implants are made of different materials such ... analysts forecast the global implantable medical devices market ...
(Date:9/2/2015)... -- About Neuroendovascular Coil A ... and ruptured brain aneurysm (a weakened area in ... as an endovascular coiling or endovascular embolization. During ... flow in an aneurysm. The endovascular coiling treatment ... interventional neuroradiologist using fluoroscopic imaging guidance. Neuroendovascular coils ...
(Date:9/2/2015)... -- About Chronic Lymphocytic Leukemia Chronic ... production of lymphocytes. It has been observed that the ... to other parts of the body. This leukemia is ... buildup of the cancerous cells. During the course of ... and lymph nodes. The course of the disease is ...
Breaking Medicine Technology:Global Implantable Medical Devices Market 2015-2019 2Global Neuroendovascular Coil Market 2015-2019 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 3