Navigation Links
Erythropoietin RIA Test

ProductsErythropoietin RIA Test
Company Diagnostic Systems Laboratories, Inc.
Item Erythropoietin RIA Test
Features 
Description Erythropoietin (EPO) is the primary known naturally-occurring stimulant of red blood cell production. The predicted molecular weight of human EPO is 18.2 kDa. Due to N-glycosylation, the circulating form of EPO has an estimated molecular mass of ~30.5 kDa. Although EPO itself appears to have a unique structure, the EPO receptor bears some homology to several other growth factor receptors, including those for interleukins 2 and 6, prolactin and growth hormone, suggesting possible functional similarities for these growth factor systems [1].

In the fetus, the liver is the major site of EPO production [1, 2, 3]. Postnatal production occurs primarily in the renal tubular epithelium, although significant continued postnatal hepatic production has been demonstrated [4]. EPO is secreted into the circulation from where it is taken up by target tissues. EPO binds to specific cell membrane receptors on erythroid progenitor cells and appears to facilitate erythrocyte differentiation, perhaps by increasing survival of the progenitor cells. Endogenous, N-glycosylated EPO is cleared at a constant rate, with a half-life estimated at 1.5 - 2 hours. The clearance rate is largely unaffected by EPO levels or tissue utilization. Therefore, circulating EPO levels reflect production rates [5].

  1. Jelkmann W Physiol Rev 72:449-489, 1992
  2. Tabbara IA Arch Intern Med 153:298-304, 1993
  3. Porter DL et al. Experiment Hematol 21:388-404, 1993
  4. Koury ST et al. Nephrol 13:78-86, 1993
  5. Spivak JL Annu Rev Med 44:243-253, 1993.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. EPO EIA Human Cytokines 021-SDX021 Erythropoietin Anemia
2. EPO (Erythropoietin) Microwell-EIA
3. Erythropoietin (EPO) ELISA
4. Erythropoietin
This probe coagulates bleeders while suction channel with trumpet valve simultaneously evacuates smoke....
Bair Hugger temperature management units are the only forced-air warming systems that can be used with an integrated, cost-effective method of fluid warming...
The Equator Convective Warmer incorporates LEVEL 1's unique, patented, temperature control technology to ensure delivery of the desired therapy to the patient....
The Affirm™ VPIII tests RNA probe technology offers a dependable, rapid means toward early identification and treatment of patients suffering from these pathogens....
Medicine Products:
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) Board ... Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will ... Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of President ...
(Date:10/13/2017)... ... ... PurhealthRX , a leading Health and Nutrition Company, is announcing the ... spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the amount ... into liquid products, while reducing costs to end users. , The team of researchers ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
(Date:10/2/2017)... -- AllianceRx Walgreens Prime, the combined central specialty pharmacy and ... manager Prime Therapeutics LLC (Prime), today officially began the ... of new signage at its headquarters in ... few other company-owned facilities across the country. This also ... whom will begin to see the AllianceRx Walgreens Prime ...
(Date:9/28/2017)... , Sept. 28, 2017 Cohen Veterans ... advance the use of wearable and home sensors for ... disorders. Early Signal Foundation, a nonprofit organization focused on ... will provide an affordable analytical system to record and ... ...
Breaking Medicine Technology: