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Coatest APC Resistance V Kit

ProductsCoatest APC Resistance V Kit
Company DiaPharma Group, Inc.
Item Coatest APC Resistance V Kit
Features 
  • Provides 100% sensitivity for the FV:Q506 mutation as determined with optical and electromechanical coagulation analyzers.
  • Validated, FDA cleared test kit removes the uncertainty of in-house research methods.
  • Normal plasma control and heterozygous FV Leiden control provided for verifying results.
  • aPTT based assay is faster, more convenient and cost effective than PCR.
  • Strongly reduces the influence of pre-analytic variables. No difference between fresh or frozen plasmas.
  • Allows for testing of plasmas from patients on oral anticoagulant (OAC) or heparin therapy.
  • Functional protein C levels will not affect the assay.
  • Utilizes the natural occurring coagulation inhibitor activated protein C (APC), not a nonspecific snake venom activator.
  • Two convenient kit sizes (Coatest APC Resistance V and Coatest APC Resistance VS) to fit your needs.
Description An APTT-based kit for the screening of factor-V-related APC resistance. The high sensitivity and specificity of the test for the factor V:Q506 mutation is obtained by prediluting the sample plasma with an excess of V-DEF Plasma bioreagent. The test design makes it possible to discriminate between heterozygous and homozygous factor V genotypes. It also allows for analysis of plasma from patients on heparin or oral anticoagulant therapy. High discrimination between genotypes with 100% sensitivity for FV:Q506. Reduces need for PCR determination. Applicable to anticoagulant treated patients. Coatest APC Resistance V exclusively detects inherited APC resistance due to mutations in the factor V gene.
Info DiaPharma Group, Inc.
Customer Service: (800) 526-5224
Web site: http://www.diapharma.com

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4. APC Resistance Mutation Detection
5. APC Resistance Profile
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