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C-Peptide of Insulin RIA Test

ProductsC-Peptide of Insulin RIA Test
Company Diagnostic Systems Laboratories, Inc.
Item C-Peptide of Insulin RIA Test
Description C-peptide of insulin is the C-terminal cleavage product produced during processing of the insulin prohormone to the mature insulin molecule. Although the C-peptide of insulin is biologically inactive, it does undergo significant liver or extra-renal metabolism and therefore has a much longer circulating half-life than insulin [1]. In addition, C-peptide assays may be analytically more sensitive than insulin assays. Measurement of the C-peptide of insulin may be useful in evaluating endogenous insulin secretion in a variety of clinical conditions [2, 3, 4].

  1. Gerich JE: Hormonal control of homeostatis. IN Galloway JA, Potvin JH, Shuman CR (eds): Diabetes Mellitus, ninth edition. Eli Lilly Co, Indianapolis, 1988, pp 46-63.
  2. Horwitz DL, et al. New Engl J Med 295:207-209, 1976.
  3. Bommen M, et al. Arch Dis Child 59:1096-1098, 1984.
  4. Field JB. Endocrinol Metab Clin North Am 18:27-43, 1989.
Info Diagnostic Systems Laboratories, Inc.
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