Navigation Links
Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-48 Myeloperoxidase

ProductsAnti-MPO ANCA EIA Auto-Immune Markers 013-MPO-48 Myeloperoxidase
Company ALPCO Diagnostics
Item Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-48 Myeloperoxidase
Features 
Description The Immunoscan MPO-ANCA Kit is an enzyme immunoassay (EIA) kit for the in vitro detection in human serum of the subclass of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) directed against myeloperoxidase to be used as an aid in the diagnosis of crescentic glomerulonephritis. ANCA are a family of autoantibodies associated with vasculitic disorders and glomerulonephritis (GN). They were first described in 1982 in patients with necrotizing GN (1) and in patients with vasculitis and GN in 1984 (2). In 1985 research on Wegeners granulomatosis (WG), independent from the earlier observations, described detection of ANCA (also called ACPA) as a diagnostic tool for Wegeners granulomatosis (3,4). In the efforts to identify the antigens for ANCA it was found that two staining patterns for ANCA could be described by indirect immunofluorescence (IIF) using ethanol fixed human neutrophils (5). One subclass of ANCA gave a finely granular, diffuse staining pattern of the cytoplasm of human neutrophils. At the 2nd International Workshop on ANCA, this subclass was termed c-ANCA for cytoplasmic staining or classical staining ANCA, and correlated to the ACPA associated with Wegeners granulomatosis (6,7). It had been shown that c-ANCA were directed against an antigen in the azurophil granules of the cytoplasm of human neutrophils (8) and later that the principal antigen was a 29kD serine protease identical to proteinase 3 or myeloblastin (9,10,11). When detected by antigen specific assays these autoantibodies are termed 29kD-ANCA or PR3-ANCA. The other subclass of ANCA yielded a perinuclear staining pattern. This was originally thought to represent granulocyte-specific anti-nuclear antibodies (GS-ANA) (5) but in sera from patients with GN such autoantibodies were shown to be due to ANCA directed against myeloperoxidase (MPO), also present in the azurophil granules in the cytoplasm of neutrophils (6,12). These antibodies were termed p-ANCA due to the perinuclear staining when detected by IIF and are termed MPO-ANCA when detected by antigen specific assays.
Info ALPCO DiagnosticsCall ALPCO Diagnostics to buy products (US and Canada only; other locations use number below) USACanada1-866-466-7731

Customer Service: (800) 592-5726
Web site: http://www.alpco.com

Related medicine products :

1. Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-96 Myeloperoxidase
2. Anti-MPO - ELISA (P-ANCA)
3. CIC (C1-q) EIA Auto-Immune Markers 001-EK-CIC Circulating Immune Complexes
4. GBM -Ab EIA Auto-Immune Markers 013-GBM-96 Glomerular Basement Membrane
5. Anti-PR3 EIA Auto-Immune Markers 013-PR3-48 Proteinase
6. Anti-PR3 EIA Auto-Immune Markers 013-PR3-96 Proteinase
7. GBM -Ab EIA Auto-Immune Markers 013-GBM-48 Glomerular Basement Membrane
8. ENA Screen EIA Auto-Immune Markers 012-MDKES1 Extractable Nuclear Antigens
9. Surgical Markers
10. TLS Surgical Markers
11. SQUEEZE-MARK Surgical Markers
Pocket Medicine's Cardiology Bundle includes the following 4 applications: Treatment Strategies in Cardiovascular Medicine, Treatment Strategies in Interventional Cardiology, Treatment Strategies in ...
The first book to translate key medical data into clear guidelines capturing the highest treatment standards for heart disease....
The perfect quick consult for the busy cardiologist, The Ultimate Echo Guide puts the most clinically essential information in an easy access format....
... Cochrane Reviews enable all those involved ... date with the very latest evidence in ... which becomes harder each year as the ... this problem by delivering the best single ...
Medicine Products:
(Date:3/28/2017)... Monica, CA (PRWEB) , ... March 28, 2017 ... ... Dr. Carson Liu of SkyLex Advanced Surgical, Inc. is thrilled to offer the ... gastric balloon procedure, and this procedure adds to SkyLex Advanced Surgical’s already ...
(Date:3/28/2017)... ... , ... With expansion and efficiency in mind, Patten Seed Company completed relocation ... plant opened in Marshallville in 2006, and a bagging and shipping facility has been ... of Patten Seed operations to the Middle Georgia location from their previous home in ...
(Date:3/28/2017)... ... ... Thank you to all who attended Capio Partners Winter 2017 Healthcare Leadership ... to providers and offered an opportunity to collaborate and network with healthcare colleagues across ... where attendees gathered for a lively discussion on trends and issues that healthcare leaders ...
(Date:3/28/2017)... ... ... Bacteria and fungi are probably not the first ingredients that come to mind when thinking ... in your diet can actually improve health outcomes. And the good news is they may ... a new peer-reviewed paper led by Maria Marco, Ph.D. , University of ...
(Date:3/27/2017)... ... March 27, 2017 , ... Drs. Bruce Trimble ... without requiring a referral. Trimble Dental offers a variety of services to ... dental implants. Whether patients have discolored, crooked or missing teeth in Eau Claire, ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... , March 28, 2017 ... expected to reach a value of USD 4.5 billion ... View Research, Inc. Proper closure of injured tissues post ... and function. Postoperative leakages occur in 3% to 15% ... They are responsible for one third of postoperative deaths ...
(Date:3/27/2017)... , March 27, 2017 ... to better understand Bayer and its partnering interests and activities ... 2010 report provides an in-depth insight into the partnering activity ... On demand company reports are prepared upon purchase to ... company data. The report will be delivered in ...
(Date:3/27/2017)... 2017  Cryoport, Inc. (NASDAQ: CYRX, CYRXW) ("Cryoport" or ... shares of common stock in an underwritten public offering ... the Securities and Exchange Commission (the "SEC"). The offering ... can be no assurance as to whether or when ... actual size or terms of the offering. Cryoport also ...
Breaking Medicine Technology: