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Androstanediol Glucuronide EIA Test

ProductsAndrostanediol Glucuronide EIA Test
Company Diagnostic Systems Laboratories, Inc.
Item Androstanediol Glucuronide EIA Test
Features 
Description Androstanediol glucuronide (3alpha-diol G) is the glucuronide conjugate of 3alpha-androstanediol, a major metabolite of dihydrotestosterone (DHT) [1,2]. 3alpha-diol G has strong androgenic activity estimated at 75% of the bioactivity of testosterone [2]. Serum 3alpha-diol G is the product of intracellular reduction of DHT, and in addition, a significant proportion of serum 3alpha-diol G is derived from DHEA-Sulfate and androstenedione.

Elevated levels of serum 3alpha-diol G have been reported in congenital adrenal hyperplasia [3,4] and in various forms of female hirsutism [1,5,6], e.g. idiopathic hirsutism and polycystic ovary disease. Serum 3alpha-diol G may be elevated in the presence of normal levels of other circulating androgens [1,5,6]. Therefore, measurement of serum 3alpha-diol G levels may be useful in the clinical evaluation and management of hirsutism and other conditions with excessive adrenal androgen production.

References

1. Rittmaster RS. Endocrin Rev 14:121-132, 1993.
2. Dorfman RI & Shipley RA. Androgens. John Wiley and Sons, Inc., New York, 1956, pp.116-128.
3. Reiner BJ, et al. J Clin Endocrinol and Metab 69:105-109, 1989.
4. Pang S, et al. J Clin Endocrinol Metab 73:166-174, 1991.
5. Horton R & Lobo RA. Clin Endocrinol Metab 15:293-306, 1986.
6. Pang S & Riddick L: Hirsutism. IN Lifshitz F: Pediatric Endocrinology, A Clinical Guide, second edition. Marcel Dekker, New York, 1990, pp. 259-291.

Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

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A sophisticated research tool that allows to see the fundus picture of the area which is being stimulated. Besides it also includes the refractive pupil camera enabling the examiner to switch between
5 mm
Cannula and irrigation extension. Overall Length 150 mm (6.25"). Light Curve.
Produce clean 0.75 mm round hole without tissue tags. Serrated squeeze action handle.
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