Navigation Links
ALS, Total ELISA Test

ProductsALS, Total ELISA Test
Company Diagnostic Systems Laboratories, Inc.
Item ALS, Total ELISA Test
Features 
Description Acid-labile subunit (ALS) is a GH dependent protein which is produced in the liver as a 578 amino acid peptide with a predicted molecular weight of 63.3 kDa. IGFs in human serum are mostly confined to a ~150 KDa GH-dependent ternary protein complex consisting of IGFBP-3, a molecule of IGF-I or IGF-II, and this unique acid-labile subunit (ALS) [1-6]. The first description of ALS was based on the observation that acidification would result in dissociation of the 150 KDa complex into acid-stable IGF (~7.5 KDa) and IGFBP-3 (~50 KDa) components while neutralization of the acidified sample would no longer support formation of the 150 KDa complex [7,8]. The existence of ALS was later confirmed by the finding that serum-derived ALS could readily convert binary IGF/IGFBP-3 complexes to the 150 KDa form and that IGFBP-3 occupancy by IGF-I or IGF-II was a prerequisite for the complex assembly [9,10] in vivo. However, ALS may also be capable of IGF-independent interaction with IGFBP-3 and as such modulate the binding capacity of IGFBP-3 for the IGF peptides [11].

  1. Jones JI et al. Endocrin Rev 16:3-34, 1995
  2. Rosenfeld RG et al. Recent Prog Horm Res 46:99-163, 1990
  3. Shimesaki S et al. Prog Growth Factor Res 1:243-266, 1991
  4. Lamson C et al. Growth Factors 5:19-28, 1991
  5. Holly JMP et al. Growth Regul 4(suppl 1):20-30, 1994
  6. Cohen P et al. Curr Opin Pediatr 6:462-467, 1994
  7. Furlanetto RM J Clin Endocrinol Metab 51:12-19, 1980
  8. Hintz RL et al in Growth hormone and other biologically active peptides. Amsterdam: Excerpta Medica 1980;133-143
  9. Baxter RC Clin Endocrinol Metab 67:265-272, 1988
  10. Baxter RC et al. J Biol Chem 264:11843-11848, 1989
  11. Barreca A et al. J Clin Endocrinol Metab 80:1318-1324, 1995.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Laserex Tango M (Total Mobile Version)
2. Bilirubin, Direct & Total
3. Bilirubin Total Reagent
4. Total Bilirubin Reagent
5. Total Protein
6. Total Protein Reagent
7. Total Protein Reagent Set
8. Iron Total (TIBC)
9. Iron (Total/Ferene)
10. Cholesterol, Total
11. Total Internal Reflection Fluorescence Microscopy
Semkin forceps with stops. Insulated....
Cushing bayonet forceps. Insulated....
Scleral knives designed for trabeculectomy and groove type incisions, scleral standard USA size....
Fechtner Trabeculectomy Marker...
Medicine Products:
(Date:5/25/2016)... CA (PRWEB) , ... May 25, 2016 , ... CloudLIMS, ... Promising Pharma and Life Sciences Tech Solution Providers list of 2016 by CIOReview. , ... Promising Pharma and Life Sciences Tech Solution Providers 2016 has been concluded with. The ...
(Date:5/25/2016)... ... May 25, 2016 , ... The Global Wellness Summit (GWS) ... integrative medical wellness offerings of Europe, a continent that pioneered the medical/wellness concept for ... from numerous pioneers in medical wellness, including Henri Chenot, Founder of the Chenot Group, ...
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... The University ... Nursing and Health Professions. She will lead a team of more than 100 full-time ... will begin her role as dean in late August. , Baker comes to USF ...
(Date:5/25/2016)... ... May 25, 2016 , ... ... has seen a significant spike in their clients' employee participation for their wellness ... health screening by implementing a high-deductible health plan with outcome-based deductible incentives. As ...
(Date:5/25/2016)... ... ... Stern Environmental Group , of Secaucus, New Jersey, working in conjunction ... Real Time Monitoring (RTM) Device. Stern Environmental Group will sell the first monitoring ... use in dormitories, shelters, and nursing homes for real time bedbug monitoring in May ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... May 23, 2016 Diplomat Pharmacy, Inc. (NYSE: DPLO) ... and Internship programs. The hands-on learning experience is a ... full-time, paid Fellowship and Internship ... . Fellows and interns are provided optional housing free ... at the Riverfront Residence Hall to foster ...
(Date:5/23/2016)... 23, 2016 Clarifying Vision - ... Monitoring, and Vision Care What can be ... going to grow at the fastest rates? This ... assessing data, trends, opportunities and prospects. ... Discover the most lucrative areas in the industry and ...
(Date:5/23/2016)... 23, 2016 Experts from various ... Medicine and the role of technology in innovative ... The First International Conference of VPS-Penn Medicine opened in ... and presence of Sheikh Nahyan bin Mubarak Al Nahyan, Minister ... Medicine, which helps provide personalized medicine and tailor-made healthcare in ...
Breaking Medicine Technology: