Navigation Links
ALS, Total ELISA Test

ProductsALS, Total ELISA Test
Company Diagnostic Systems Laboratories, Inc.
Item ALS, Total ELISA Test
Features 
Description Acid-labile subunit (ALS) is a GH dependent protein which is produced in the liver as a 578 amino acid peptide with a predicted molecular weight of 63.3 kDa. IGFs in human serum are mostly confined to a ~150 KDa GH-dependent ternary protein complex consisting of IGFBP-3, a molecule of IGF-I or IGF-II, and this unique acid-labile subunit (ALS) [1-6]. The first description of ALS was based on the observation that acidification would result in dissociation of the 150 KDa complex into acid-stable IGF (~7.5 KDa) and IGFBP-3 (~50 KDa) components while neutralization of the acidified sample would no longer support formation of the 150 KDa complex [7,8]. The existence of ALS was later confirmed by the finding that serum-derived ALS could readily convert binary IGF/IGFBP-3 complexes to the 150 KDa form and that IGFBP-3 occupancy by IGF-I or IGF-II was a prerequisite for the complex assembly [9,10] in vivo. However, ALS may also be capable of IGF-independent interaction with IGFBP-3 and as such modulate the binding capacity of IGFBP-3 for the IGF peptides [11].

  1. Jones JI et al. Endocrin Rev 16:3-34, 1995
  2. Rosenfeld RG et al. Recent Prog Horm Res 46:99-163, 1990
  3. Shimesaki S et al. Prog Growth Factor Res 1:243-266, 1991
  4. Lamson C et al. Growth Factors 5:19-28, 1991
  5. Holly JMP et al. Growth Regul 4(suppl 1):20-30, 1994
  6. Cohen P et al. Curr Opin Pediatr 6:462-467, 1994
  7. Furlanetto RM J Clin Endocrinol Metab 51:12-19, 1980
  8. Hintz RL et al in Growth hormone and other biologically active peptides. Amsterdam: Excerpta Medica 1980;133-143
  9. Baxter RC Clin Endocrinol Metab 67:265-272, 1988
  10. Baxter RC et al. J Biol Chem 264:11843-11848, 1989
  11. Barreca A et al. J Clin Endocrinol Metab 80:1318-1324, 1995.
Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. Laserex Tango M (Total Mobile Version)
2. Bilirubin, Direct & Total
3. Bilirubin Total Reagent
4. Total Bilirubin Reagent
5. Total Protein
6. Total Protein Reagent
7. Total Protein Reagent Set
8. Iron Total (TIBC)
9. Iron (Total/Ferene)
10. Cholesterol, Total
11. Total Internal Reflection Fluorescence Microscopy
... disposable concentric needle has a platinum-alloy core, ... plug connector. Needles sold in packages of ... with 5-pin DIN connector is sold separately. ... may be autoclaved or disinfected (page 34). ...
... The RSV OIA test features a ... your results. Approved for children under age ... provides an answer in just over 15 ... will enable you to decrease costs for ...
... Rotavirus is the most ... accounting for 5% of pediatric ... for children under 5 years. ... answer to rule in or ...
... The Acceava Group A Strep test delivers excellent ... A Strep with a simple, easy-to-use test that ... Thermos value-added services enable you to provide improved ... staffing requirements of waived laboratories. Find out what ...
Medicine Products:
(Date:6/25/2016)... Washington, D.C. (PRWEB) , ... June 25, 2016 ... ... will discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June ... share their work on several important health care topics including advance care planning, ...
(Date:6/25/2016)... Long Beach, CA (PRWEB) , ... June 25, 2016 , ... ... from UCLA with Magna Cum Laude and his M.D from the David Geffen School ... San Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Living, is proud to recognize Dr. Barry M. Weintraub as a prominent plastic ... most beautiful women in the world, and the most handsome men, look naturally ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016 Jazz Pharmaceuticals plc (Nasdaq: ... under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as ... Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: CPXX ) ... Daylight Time). As previously announced on May ... definitive merger agreement under which Jazz Pharmaceuticals has commenced ...
(Date:6/26/2016)... -- Story Highlights: , ... health care industry is causing providers to review operating ... offers a suite of solutions for health care providers ... optimization: labor resource analysis, revenue cycle optimization and physician ... and better economics ...
(Date:6/24/2016)... 24, 2016  Collagen Matrix, Inc., ("Collagen Matrix") ... manufacturing of collagen and mineral based medical devices ... Bill Messer has joined the company ... leverage the growing portfolio of oral surgery, neurosurgery, ... Bill joins the Collagen Matrix executive team as ...
Breaking Medicine Technology: