Navigation Links
17a-OH Progesterone RIA Test

Products17a-OH Progesterone RIA Test
Company Diagnostic Systems Laboratories, Inc.
Item 17a-OH Progesterone RIA Test
Features 
Description 17alpha-OH-Progesterone (17alpha-OH-P) is a steroid produced in the adrenal gland and gonads and has no defined physiological role except as a precursor molecule. In the adrenal glands, 17alpha-OH-P can be converted to cortisol by the sequential actions of 21-hyroxylase and 11-hyroxylase. In both the adrenal glands and ovaries, 17alpha-OH-P can be converted to androstenedione (a precursor for testosterone and estradiol), by 17,20-lyase. Measurement of circulating 17alpha-OH-P levels is a standard tool for clinical assessment of 21-hydroxylase deficiency, the most common cause of congenital adrenal hyperplasia (CAH) [1,2,3]. Due to the decreased activity of 21-hydroxylase in CAH, 17alpha-OH-P cannot be efficiently converted to cortisol and instead, accumulates in large amounts which are shunted into the androgen biosynthetic pathway. The resulting elevations in androgen levels cause progressively severe virilization beginning during fetal life and infancy. In addition, 21-hydroxylase is required for aldosterone synthesis, and approximately 50% of cases of 21-hydroxylase deficiency suffer from potentially fatal salt-wasting. Elevated serum 17alpha-OH-P levels are found in virtually all cases of classical 21-hydroxylase deficiency. 17alpha-OH-P levels are useful in monitoring steroid replacement therapy [1,2,3].

References

1. New MI & Levine LS: Congenital Adrenal Hyperplasia. (Monographs on Endocrinology, vol. 26) Springer-Verlag, Berlin, 1984.
2. Hughes IA & Winter JSD. J Pediatr 88:766-773, 1976.
3. Petersen KE & Christensen T. Acta P diatr Scand 68:205-211, 1979.

Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. 17a-OH Progesterone EIA Test
2. Progesterone EIA Reproductive Markers 020-DR-1561
3. 17-OH Progesterone EIA Reproductive Markers 020-DR-1292 Reproductive Hormones
4. 17 alpha OH Progesterone ELISA Test Kit
5. Progesterone ELISA
6. Progesterone RIA Test
7. Progesterone EIA Test
8. ACE Competitive Enzyme Immunoassay for Progesterone
9. Progesterone RIA Kit
10. Estrogen/Progesterone Receptor Assay, Paraffin
11. Progesterone
... Cepheid Smart GBS test, performed on ... in vitro diagnostic test designed to ... in vaginal/rectal specimens using proven real-time ... LIM broth cultures, Smart GBS delivers ...
...
... primers and a FAM-labeled probe that is ... In addition, this ASR contains primers and ... processing control. This ASR requires an instrument ... reporter dyes such as the Cepheid SmartCycler ...
... Protection Device features the ability to use ... lesion and a pre-loaded nitinol filter with ... Offering a fully rapid exchange system, the ... the indicated applications:, Carotid Indication - ,The ...
Medicine Products:
(Date:12/8/2016)... ... December 08, 2016 , ... ... distinction by the Undersea and Hyperbaric Medical Society (UHMS), the leading authority in ... and patient safety. Only a few hospitals and facilities have earned this distinction. ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... to announce that “Natural Language Processing–Enabled and Conventional Data Capture Methods for Input ... JMIR Medical Informatics . , Results of the comparative usability study demonstrate that ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... CURE Media ... centers and advocacy groups, has aligned with Upstage Lung Cancer in efforts to combat ... the announcement, Michael J. Hennessy, Jr said, “CURE Media Group is honored to team ...
(Date:12/8/2016)... ... ... Fitness Camp (PFC) and The Chopra Center for Wellbeing announced today the launch of ... headquarters of Omni La Costa Resort & Spa in San Diego. , Chopra FIT ... development, a healthy lifestyle, or mental and physical healing. The week-long wellness program combines ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... and development solutions for drugs, biologics and consumer health products, today announced that ... set up in 2006 as a non-profit organization to unite pharmaceutical and healthcare ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... QUEBEC CITY , Dec. 8, 2016 /PRNewswire/ ... key US patents for improving the accuracy, reproducibility ... CD images in long and small bone orthopaedic ... proprietary approach to creating personalized orthopaedic restorations based ... create personalized orthopaedic restorations, the company harnesses the ...
(Date:12/8/2016)... , Dec. 8, 2016  A new study ... that the use of opioid therapy to treat chronic ... the likelihood of more harmful consequences, including death. ... M.D., and Zankhana Mehta , M.D., authored the ... on chronic opioid therapy. The study was published in ...
(Date:12/8/2016)... 2016 Information products and services provider ... Scopus , the world,s largest abstract and citation database of ... for journals from over 5,000 publishers. The new set of metrics ... to and when to adjust a journal,s editorial strategy. ... , , ...
Breaking Medicine Technology: