Navigation Links
17a-OH Progesterone RIA Test

Products17a-OH Progesterone RIA Test
Company Diagnostic Systems Laboratories, Inc.
Item 17a-OH Progesterone RIA Test
Features 
Description 17alpha-OH-Progesterone (17alpha-OH-P) is a steroid produced in the adrenal gland and gonads and has no defined physiological role except as a precursor molecule. In the adrenal glands, 17alpha-OH-P can be converted to cortisol by the sequential actions of 21-hyroxylase and 11-hyroxylase. In both the adrenal glands and ovaries, 17alpha-OH-P can be converted to androstenedione (a precursor for testosterone and estradiol), by 17,20-lyase. Measurement of circulating 17alpha-OH-P levels is a standard tool for clinical assessment of 21-hydroxylase deficiency, the most common cause of congenital adrenal hyperplasia (CAH) [1,2,3]. Due to the decreased activity of 21-hydroxylase in CAH, 17alpha-OH-P cannot be efficiently converted to cortisol and instead, accumulates in large amounts which are shunted into the androgen biosynthetic pathway. The resulting elevations in androgen levels cause progressively severe virilization beginning during fetal life and infancy. In addition, 21-hydroxylase is required for aldosterone synthesis, and approximately 50% of cases of 21-hydroxylase deficiency suffer from potentially fatal salt-wasting. Elevated serum 17alpha-OH-P levels are found in virtually all cases of classical 21-hydroxylase deficiency. 17alpha-OH-P levels are useful in monitoring steroid replacement therapy [1,2,3].

References

1. New MI & Levine LS: Congenital Adrenal Hyperplasia. (Monographs on Endocrinology, vol. 26) Springer-Verlag, Berlin, 1984.
2. Hughes IA & Winter JSD. J Pediatr 88:766-773, 1976.
3. Petersen KE & Christensen T. Acta P diatr Scand 68:205-211, 1979.

Info Diagnostic Systems Laboratories, Inc.
Customer Service: (800) 231-7970
Web site: http://www.dslabs.com

Related medicine products :

1. 17a-OH Progesterone EIA Test
2. Progesterone EIA Reproductive Markers 020-DR-1561
3. 17-OH Progesterone EIA Reproductive Markers 020-DR-1292 Reproductive Hormones
4. 17 alpha OH Progesterone ELISA Test Kit
5. Progesterone ELISA
6. Progesterone RIA Test
7. Progesterone EIA Test
8. ACE Competitive Enzyme Immunoassay for Progesterone
9. Progesterone RIA Kit
10. Estrogen/Progesterone Receptor Assay, Paraffin
11. Progesterone
... TruFlow™ Oxygen flowmeter with a Lexan®inner calibrated ... calibration and manufacturing defects. A wide range ... needs. Also available with all popular inlet ... and double unit configurations. Our extra large ...
... flowmeter with a Lexan®inner calibrated flow tube ... manufacturing defects. A wide range of configurations ... available with all popular inlet connections, a ... unit configurations. Our extra large knob coupled ...
... with a Lexan®inner calibrated flow tube has ... defects. A wide range of configurations are ... with all popular inlet connections, a 50 ... configurations. Our extra large knob coupled with ...
... entire series of time-tested Timeter® Classic Flowmeters ... of care providers and patients alike. You ... can see it in the craftsmanship. You ... after year. Every Timeter® Classic Flowmeter is ...
Medicine Products:
(Date:10/13/2017)... ... 13, 2017 , ... While it’s often important to take certain medications during ... Austin, Texas, has identified a solution. , She developed a prototype for MOTION LIGHT-UP ... such, it eliminates the need to turn on a light when taking medication during ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of ... ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership in ... It also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ... the introduction of an innovative new design of the shoulder pad. The shoulder ... maximum comfort while controlling your pain while using cold therapy. By utilizing ice and ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... The Rebound mobile app is poised to become a vital ... prescription drug addiction. The app empowers users to develop an ... their dosage in a safe, controlled manner while maximizing well-being. ... 100,000 people to sign up will enjoy 3 months of ... ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a ... targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , ...
Breaking Medicine Technology: