Navigation Links
Zactima Receives Fast Track Designation By The FDA

ZACTIMA a product of AstraZeneca has been granted fast track designation by the US Food and Drug Administration (FDA). The drug also received the orphan drug designation // recently for treatment of anaplastic, medullary, follicular, locally advanced and metastatic medullary thyroid cancer. Following the approval, investigation of the drug in the treatment of medullary thyroid carcinoma is expected to accelerate further.

Medullary thyroid cancer accounts for 5 to 10% of all thyroid cancers. Surgery, nuclear medicine (treatment with radioactive iodine), hormonal manipulation, external beam radiotherapy (direction of radiation to kill cancer cells from outside the body) and chemotherapy represent some of the available treatment options.

Presently, there is no satisfactory chemotherapy regimen or other treatment modality for the cure of advanced thyroid cancer. Only those drugs, used for the treatment of severe diseases for which there is an unfulfilled medical need would be granted fast-track status by the FDA.

The fast track review by the FDA would be of immense help in the development of the drug and regulation of the submission process. The pharmaceutical company is currently involved in Phase II clinical trials of the drug, directed against metastatic or locally advanced medullary thyroid cancer.

The compound is believed to play a major role in the inhibition of the growth and spread of the thyroid cancer by participating in vital cell signalling pathways. Vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EFGR) participate in the inhibition pathway while REarranged during Transfection (RET) tyrosine kinases can accelerate the growth of the same.

If the treatment is found to be successful, then we might soon have a new treatment modality for the treatment of medullary thyroid cancer.


'"/>




Page: 1

Related medicine news :

1. Fifth US Patient Receives Artificial Heart
2. Northfield Labs Receives FDA Comments
3. British MPs Say Prostate Cancer Receives Low Priority in the NHS
4. Abbott Receives CE Mark Certification
5. East London Receives World Class New Private Hospital Facility
6. Brinda Karat Receives Legal Notice over Ramdev Issue
7. Quake-Hit Pakistan Receives 30 Field Hospitals From Cuba
8. Medtronic’s Insulin Pump Receives Regulatory Approva
9. Aurobindo Receives Approval from USFDA for anti-AIDS drug
10. Sunscreen Blocking UVA Radiation Receives Federal Approval
11. Eddie Thompson Receives Advanced Cancer Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Zactima Receives Fast Track Designation The FDA

(Date:9/30/2014)... 2014 Lea Blackwell, M.D., a Breast ... patients a new, more practical and comfortable option for ... mastectomies, biopsies and lumpectomy surgeries use special bras after ... seeing her patients describe the bra as scratchy, uncomfortable ... new bra in her spare time. , Ilona ...
(Date:9/30/2014)... California (PRWEB) September 30, 2014 ... to reach USD 8,020.1 million by 2020, according ... Inc. Growing demand for personalized medicine and theranostics, ... technologies are expected to be key factors driving ... the growing global base of geriatric population and ...
(Date:9/30/2014)... During this online virtual event, hear ... including achieving hormonal balance, relieving menopause symptoms, breast ... , The details of the virtual ... 2014, Location: Online Event, Registration: Complimentary , Visit ... Monday, October 6th, Steven F. Hotze, M.D., David ...
(Date:9/30/2014)... Oxnard, CA (PRWEB) September 30, 2014 ... the Anacapa Dental Art Institute in Oxnard and Thousand ... Bangalore today and tomorrow to provide training on full ... previous dental work, placing implants, providing cosmetic dentistry, correcting ... Dr. Jivraj said. , Dr. Jivraj, who has traveled ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 ... ADVISORY** , From:        Hope For ... 910.554.1505, abarnwell(at)hopeforthewarriors(dot)org , ... Celebration , Date:        Thursday, October ... Army and Navy Club, ...
Breaking Medicine News(10 mins):Health News:Surgeon Creates New Bra for Breast Cancer Patients, Post-Surgery 2Health News:Surgeon Creates New Bra for Breast Cancer Patients, Post-Surgery 3Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 2Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 3Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 4Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 5Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 6Health News:Hotze Health & Wellness Center Announces First Natural Health Summit 2Health News:World-Renowned Dental Implant Expert, International Instructor in India Speaking about Reconstructive Dentistry 2Health News:World-Renowned Dental Implant Expert, International Instructor in India Speaking about Reconstructive Dentistry 3Health News:World-Renowned Dental Implant Expert, International Instructor in India Speaking about Reconstructive Dentistry 4Health News:World-Renowned Dental Implant Expert, International Instructor in India Speaking about Reconstructive Dentistry 5Health News:Hope For The Warriors' Got Heart, Give Hope Celebration Media Advisory 2
... American Oriental,Bioengineering, Inc. (NYSE: AOB ), ... nutraceutical products in China, today,announced that the Company ... Company will present at the CIBC World Markets ... at the Waldorf-Astoria,Hotel in New York City. Management ...
... Now Able to Submit Aetna Claims at No Cost ... Inc., a leading,healthcare technology company focused on providing innovative ... today,announced it has expanded its relationship with Aetna to ... 1, 2007. Aetna is a leading,diversified health care benefits ...
... Health Care Costs, DALLAS, Oct. 26 ... M.D., M.P.H., Cooper Aerobics Enterprises,Inc., announced today its ... Enterprises purchased Health At Work, a licensed,health, life ... Cooper Benefits,LLC. Cooper Benefits merges traditional employee ...
... WEST BERLIN, N.J., Oct. 26 EP MedSystems,(Nasdaq: EPMD ) announces the following ... 11/01/2007 @ 4:30 pm EST, Where: ... Simply log on to the web at the ... person of EP MedSystems, ...
... Jack Group, Inc.,(MattsonJack) announces the release of its ... help clients make strategic,decisions based on an in-depth ... conditions. Comorbidity Database(TM) consists of,two modules: Comorbidity Database(TM) ... and Comorbidity Database(TM) -- Med 2.0, which features ...
... Institutet have shown that hysterectomy a common operation ... the risk of urinary incontinence. Their results, which ... Lancet. , Hysterectomy is the most common gynaecological ... as a cure for benign medical problems in order ...
Cached Medicine News:Health News:American Oriental Bioengineering Announces Participation in November Healthcare Conferences 2Health News:MD On-Line Expands Relationship with Aetna for Direct Claim Submission 2Health News:An Industry First: New Cooper Health Company Makes Group Employee Benefits Consulting and Wellness Program Design a Package Deal 2Health News:An Industry First: New Cooper Health Company Makes Group Employee Benefits Consulting and Wellness Program Design a Package Deal 3Health News:An Industry First: New Cooper Health Company Makes Group Employee Benefits Consulting and Wellness Program Design a Package Deal 4Health News:Webcast Alert: EP MedSystems Announces EP MedSystems Third Quarter 2007 Earnings Conference Call Webcast 2Health News:The Mattson Jack Group, Inc. Announces the Release of the New Comorbidity Database(TM) 2
(Date:9/30/2014)... 30, 2014  Come fall, many children, teenagers, and ... they want to be for Halloween. And, a number ... decorative contact lenses bought without a prescription. ... people purchase and wear contact lenses without a prescription. ... ® consumer survey, 17 percent of Americans have ...
(Date:9/30/2014)... Sept. 30, 2014 Chindex ... CHDX ) today announced the completion of its acquisition ... per share in cash.  Healthy Harmony is an affiliate ... and Ms. Roberta Lipson , the CEO of ... was adopted by Chindex,s stockholders at a special meeting ...
(Date:9/30/2014)... CARLOS, Calif. , Sept. 30, 2014 /PRNewswire/ ... an additional $10 million investment from current investors ... The additional financing was completed following achievement of ... lead antibody program, and represents an extension of ... closed in December 2012. With this additional financing, ...
Breaking Medicine Technology:The Spooky Truth: What You Need To Know About Contact Lens Hygiene 2The Spooky Truth: What You Need To Know About Contact Lens Hygiene 3Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 2Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 3Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 4Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 5Allakos Inc. Raises Additional $10 Million to Expand its Portfolio and Fund Development of an Additional Antibody for Allergic and Inflammatory Diseases 2Allakos Inc. Raises Additional $10 Million to Expand its Portfolio and Fund Development of an Additional Antibody for Allergic and Inflammatory Diseases 3Allakos Inc. Raises Additional $10 Million to Expand its Portfolio and Fund Development of an Additional Antibody for Allergic and Inflammatory Diseases 4
... BALTIMORE, May 5, 2011 New data presented ... Interventions (SCAI) Scientific Sessions are the first to ... within implantable cardioverter defibrillators (ICDs) to detect restricted ... disease patients outside the hospital setting. Preliminary results ...
... 5, 2011 Echo Therapeutics, Inc. (OTCBB: ECTE), a ... wireless, transdermal continuous glucose monitoring (tCGM) system and the ... the relocation of its corporate headquarters from Franklin, MA ... located in the heart of Philadelphia,s Center City Business ...
Cached Medicine Technology:New Data Provide First Look at Ability to Detect Life-Threatening Heart Problems in Some High-Risk Patients 2New Data Provide First Look at Ability to Detect Life-Threatening Heart Problems in Some High-Risk Patients 3Echo Therapeutics Expands Into New Headquarters in Philadelphia 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: