Navigation Links
Zactima Receives Fast Track Designation By The FDA

ZACTIMA a product of AstraZeneca has been granted fast track designation by the US Food and Drug Administration (FDA). The drug also received the orphan drug designation // recently for treatment of anaplastic, medullary, follicular, locally advanced and metastatic medullary thyroid cancer. Following the approval, investigation of the drug in the treatment of medullary thyroid carcinoma is expected to accelerate further.

Medullary thyroid cancer accounts for 5 to 10% of all thyroid cancers. Surgery, nuclear medicine (treatment with radioactive iodine), hormonal manipulation, external beam radiotherapy (direction of radiation to kill cancer cells from outside the body) and chemotherapy represent some of the available treatment options.

Presently, there is no satisfactory chemotherapy regimen or other treatment modality for the cure of advanced thyroid cancer. Only those drugs, used for the treatment of severe diseases for which there is an unfulfilled medical need would be granted fast-track status by the FDA.

The fast track review by the FDA would be of immense help in the development of the drug and regulation of the submission process. The pharmaceutical company is currently involved in Phase II clinical trials of the drug, directed against metastatic or locally advanced medullary thyroid cancer.

The compound is believed to play a major role in the inhibition of the growth and spread of the thyroid cancer by participating in vital cell signalling pathways. Vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EFGR) participate in the inhibition pathway while REarranged during Transfection (RET) tyrosine kinases can accelerate the growth of the same.

If the treatment is found to be successful, then we might soon have a new treatment modality for the treatment of medullary thyroid cancer.


'"/>




Page: 1

Related medicine news :

1. Fifth US Patient Receives Artificial Heart
2. Northfield Labs Receives FDA Comments
3. British MPs Say Prostate Cancer Receives Low Priority in the NHS
4. Abbott Receives CE Mark Certification
5. East London Receives World Class New Private Hospital Facility
6. Brinda Karat Receives Legal Notice over Ramdev Issue
7. Quake-Hit Pakistan Receives 30 Field Hospitals From Cuba
8. Medtronic’s Insulin Pump Receives Regulatory Approva
9. Aurobindo Receives Approval from USFDA for anti-AIDS drug
10. Sunscreen Blocking UVA Radiation Receives Federal Approval
11. Eddie Thompson Receives Advanced Cancer Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Zactima Receives Fast Track Designation The FDA

(Date:3/4/2015)... March 04, 2015 TROY Healthcare Solutions ... which provides the ultimate level of security for prescriptions, ... Hilton Houston Plaza Medical Center located at 6633 Travis ... Beginning at 7 AM, TROY Healthcare Solutions will host ... Solutions will offer brief presentations each hour to introduce ...
(Date:3/4/2015)... Smokers across America are the target of ... Smokers' from Aqua-Tine, the new brand that helps you ... to establish a clear point of view for your ... Love Smokers' elevates the Aqua-Tine brand, gives it an ... bold tone of voice that is also genuinely thoughtful ...
(Date:3/4/2015)... (PRWEB) March 04, 2015 Starting February ... LASIK and PRK procedures at their new location in ... Dr. Joseph King and Dr. Gabriel Chu also provide ... in Surrey is named Fraser Valley Cataract and Laser ... accredited by the College of Physicians and Surgeons of ...
(Date:3/4/2015)... " Optrix by Body Glove ” ... Tech Report, which takes a look at the latest ... Scott Steinberg, a special reporter for NewsWatch and a ... viewers how they have an ultra-rugged, waterproof case with ... a major player at the Consumer Electronics Show in ...
(Date:3/4/2015)... CA (PRWEB) March 04, 2015 The ... dialogue and lyrical music, will be performed by the ... Hills Estates, CA, this March 6-22, 2015, on Fridays, ... Center at Peninsula High School (27118 Silver Spur ... one hour before the program or may be purchased ...
Breaking Medicine News(10 mins):Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 2Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 3Health News:The Brand Behind The Bold and Provocative Ad Campaign 'We Love Smokers' 2Health News:The Brand Behind The Bold and Provocative Ad Campaign 'We Love Smokers' 3Health News:King LASIK relocates to Surrey, British Columbia 2Health News:A Waterproof Phone Case with an Interchangeable Lens System was Featured on NewsWatch Television on January 30, 2015 2Health News:The New Mel Brooks Musical Young Frankenstein Performance March 6-March 22, 2015, by the Award Winning Drama Department at Peninsula High School, Rolling Hills 2
... Loma Linda University Children,s Hospital (LLUCH) was ... its efforts in giving breastfeeding mothers the information, ... continue breastfeeding their babies. LLUCH is the first ... this status. "Because children,s hospitals have ...
... Pa., Feb. 2 Employers spend more than $13 billion ... - dubbed the world,s number one health threat by the ... are more prone to injury and accidents and incur higher ... a guidepost to help employers address this issue. Health ...
... of Health and Human Services (HHS) Secretary has ... by the Healthcare Information Technology Standards Panel ... documents that harmonize and recommend the technical standards ... records and help support the nationwide exchange of ...
... Feb. 2 Pet advocates are encouraging,pet owners to ... National Pet,Dental Health Month this February. And it ... provider PetFirst Healthcare saw claims,for illnesses related to oral-health ... "Many pet owners don,t place as much ...
... new study makes important new findings on the role ... confirming that the use of estrogen plus progesterone increases ... far more than estrogen-only; suggesting a two-year "safe" period ... that the increased risk for ductal cancers observed in ...
... Improving Formulary Placement of Newer Entrants to ... from HealthLeaders-InterStudy and Fingertip FormularyNASHVILLE, ... HealthLeaders-InterStudy and Fingertip Formulary find that ... expect to reimburse both Bristol-Myers Squibb/AstraZeneca,s Onglyza ...
Cached Medicine News:Health News:LLUCH is First Children's Hospital in Nation to Receive 'Baby-Friendly' Designation 2Health News:Health Advocate Releases Obesity White Paper: Strategies and Programs to Reduce Obesity in the Workplace 2Health News:Health Advocate Releases Obesity White Paper: Strategies and Programs to Reduce Obesity in the Workplace 3Health News:HHS Secretary Recognizes Products of HITSP Standards Work 2Health News:HHS Secretary Recognizes Products of HITSP Standards Work 3Health News:HHS Secretary Recognizes Products of HITSP Standards Work 4Health News:Pet Dental Claims Skyrocket 2Health News:Study identifies potential 'safe period' for hormone replacement use 2Health News:Less Than Two-Thirds of Surveyed Pharmacy Directors Expect to Reimburse Both Onglyza and Alogliptin Once They are Available for the Treatment of Type 2 Diabetes 2Health News:Less Than Two-Thirds of Surveyed Pharmacy Directors Expect to Reimburse Both Onglyza and Alogliptin Once They are Available for the Treatment of Type 2 Diabetes 3
(Date:3/4/2015)... 2015  NxStage Medical, Inc. (Nasdaq: NXTM ), ... Jeffrey H. Burbank , Chief Executive Officer, will present ... Miami, FL on Wednesday, March 11 th ... event will be made available at http://ir.nxstage.com  at ... NxStage Medical, Inc. (Nasdaq: NXTM ) ...
(Date:3/4/2015)... XBiotech announced today that results from ... moderate to severe plaque psoriasis have been published ... evaluated the potential benefit of MABp1, the Company,s ... (IL-1a). IL-1a is a pro-inflammatory cytokine present in ... The Company claims that blockade of IL-1a can ...
(Date:3/4/2015)... Pa. , March 4, 2015  Results of ... 100 Consecutive Cases Using MarginProbe for Intra-Operative Positive Margin ... poster session at the 32 nd Annual Miami ... study, conducted by Moshe Papa , MD, FACS, ... at Tel Aviv University, reports an analysis of MarginProbe,s ...
Breaking Medicine Technology:NxStage to Present at the Barclays Capital Global Healthcare Conference 2XBiotech Announces Phase II Psoriasis Study Results in JAMA Dermatology 2New Study Shows Breast Re-excision Rates Significantly Reduced in 100 Consecutive Cases 2
... Oct. 24, 2011 Pinnacle Biologics, Inc., a privately ... filed an Orphan Drug Designation (ODD) for their product ... surgery in the treatment of Malignant Pleural Mesothelioma. ... affecting the lining of the lungs. It is a ...
... Liberate Cosmetic Surgery hopes to raise awareness of some ... within the cosmetic surgery industry through the launch of a ... on-going activity on the subject, such as question and answer ... some exciting new initiatives online, that it hopes people from ...
Cached Medicine Technology:Pinnacle Biologics Files for Orphan Drug Designation for PHOTOFRIN® in the Treatment of Patients with Malignant Mesothelioma. 2Pinnacle Biologics Files for Orphan Drug Designation for PHOTOFRIN® in the Treatment of Patients with Malignant Mesothelioma. 3Pinnacle Biologics Files for Orphan Drug Designation for PHOTOFRIN® in the Treatment of Patients with Malignant Mesothelioma. 4Liberate Cosmetic Surgery aims to Highlight Cosmetic Surgery Industry Issues 2
... in 1937 with the Aviator style created ... Luxottica Group's brand portfolio in 1999. Worn ... since day one, Ray-Bans styles are sunglasses ... sunglasses in the world. Characterized by high ...
... manufacturing the Anne Klein brand under license ... are designed for an all-female market. The ... eyewear identifies herself with the typical modern ... who is image-conscious and quality-conscious and loves ...
... in mind, making eyewear that is kid-tough ... Its not surprising that Disney eyewear was ... selling childrens collection from 1997-2003. Part of ... ability to keep pace with todays fashion ...
... frame mounting technology has redefined rimless collections ... taper at the end of each frame ... of the bushing that mounts within the ... a secure fit is created that far ...
Medicine Products: