Navigation Links
Yale Researchers Named Ellison Foundation Senior Scholars in Aging

New Haven, Conn. — Two distinguished Yale scientists have been named Senior Scholars in Aging research by the Ellison Medical Foundation, a four-year award made// to established investigators for research into understanding development processes that affect lifespan, and age-related diseases and disabilities.

Named at Yale are Frank J. Slack, associate professor of molecular, cellular and developmental biology, and Sandra L. Wolin, professor of cell biology and of molecular biophysics & biochemistry.

Frank Slack studies the genetic switches that control development, and “aging” as a developmental process. According to Slack, “Changes in gene expression in aged adults — across many species — do not solely seem to be a response to mounting cellular damage. Rather, a conserved, developmentally-timed regulation of gene activity during young adulthood seems to control features of aging.”

Past research on C. elegans and Drosophila, laboratory round worms and fruit flies, demonstrated that in early adulthood these animals turn off a conserved group of genes that mobilize energy from food, and turn on stress response genes. There is a similar trend in human brain tissue, where the switch occurs at around age 40, implying that aging, or specifically the time of death, is under a timed control at the genetic level.

“We found that genes that regulate the timing of events during C. elegans development also regulate timing of aging and death during adulthood,” said Slack. Consistent with the lifespan analysis, mutants he studied were stress-sensitive and aged prematurely. Since some of these genes coded for small non-coding RNAs called microRNAs, his work provided some of the best evidence for a novel role for microRNAs in aging, and opened the potential of using microRNAs to regulate human health during aging.

Slack joined the Yale faculty in 2000 after completing his undergraduate work in microbiology, biochemistry and molecu
'"/>




Page: 1 2 3

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
(Date:6/30/2015)... Detroit, MI (PRWEB) , ... June 30, 2015 , ... Ticket Down is a reputable ... The 44-year-old native of Detroit, MI, Kid Rock, is hitting the road again this summer ... rock, country, and hip hop superstar kicked off his summer tour this year at the ...
(Date:6/30/2015)... ... ... a reliable source for last minute tickets for The Rolling Stones at Carter Finley ... in conjunction with their 2015 “Zip Code Tour.” , The Stones have been rocking for ... Some of the most beloved songs that this iconic group has performed over the ...
(Date:6/30/2015)... ... June 30, 2015 , ... According to research by European archeologists that was ... three to four hundred thousand years ago likely knew that eating a balanced diet ... in fossilized, ancient dental plaque, researchers were able to find evidence of plant fibers, ...
(Date:6/30/2015)... ... June 30, 2015 , ... Villa Health ... care centers in the country. To spread the word, Villa Health Care Center ... facility is, indeed, worthy of five stars. While Medicare centers its rating on ...
(Date:6/30/2015)... NJ (PRWEB) , ... June 30, 2015 , ... Trenton ... one of the first Medicaid Accountable Care Organizations (ACO) in the State, serving the ... July 1. , The Trenton Health Team ACO draws on the collaborative structure of ...
Breaking Medicine News(10 mins):Health News:Cheap Kid Rock Tickets at the DTE Energy Music Theatre in Clarkston: Ticket Down Has Slashed Prices On All Kid Rock Tickets at DTE in the Detroit Metro Area 2Health News:The Rolling Stones Tickets in Raleigh at Carter Finley Stadium: Ticket Down Offers Last Minute Tickets for the Rolling Stones and Avett Brothers in Raleigh 2Health News:Recent Article Detailing Research on 400,000 Year Old Dental Plaque Shows Ancestral Understanding of Healthy Eating and Basic Oral Hygiene, Says Feiz Dental 2Health News:Recent Article Detailing Research on 400,000 Year Old Dental Plaque Shows Ancestral Understanding of Healthy Eating and Basic Oral Hygiene, Says Feiz Dental 3Health News:Villa Health Care Center Announces Highest Care Rating in New Video 2Health News:Trenton Health Team Certified as Medicaid Accountable Care Organization 2Health News:Trenton Health Team Certified as Medicaid Accountable Care Organization 3
... Donations needed for ... ... global health expert, Dr. Daniel Carucci, traveled to Haiti in the early morning to deliver ... to assess the situation on the ground to determine the best way to help the ...
... , , HARTFORD, Conn. , ... negotiated in the nation,s capital, but people struggling with the lack of ... when the National Association of Free Clinics (NAFC) holds its next C.A.R.E. ... will be the fifth in a series of large, mostly one-day C.A.R.E. ...
... , Troubled union still struggling to stop fair elections for thousands ... Jan. 15 After a year of stalling union elections ... officials have cast themselves as champions of democracy in a cynical move ... has blocked or delayed elections at more than 360 healthcare facilities in ...
... , , ... Lotus Pharmaceuticals, Inc.,(OTC Bulletin Board: LTUS) ("Lotus" or the "Company"), a ... pharmaceutical,products in the People,s Republic of China ("PRC"), today ... McLaughlin & Stern LLP. , The Company ...
... BOSTON , Jan. 15 Healthcare Data ... New England Quality Care Alliance (NEQCA), Tufts Medical Center Physicians ... use of their proprietary HDS Analyst(SM) tool. The contract was ... would meet the data monitoring needs of NEQCA and Tufts ...
... , PIEDMONT, Mo. , Jan. ... veterinary software, today announced a new veterinary web site ... creating and hosting web sites for veterinary clinics, PetWise ... access to their pet health information and medical records ...
Cached Medicine News:Health News:Update from Haiti: United Nations Foundation Vice President for Global Health Delivers Medical Supplies in Port-au-Prince 2Health News:Update from Haiti: United Nations Foundation Vice President for Global Health Delivers Medical Supplies in Port-au-Prince 3Health News:Free Health Care for the Uninsured Is Coming to Connecticut in February 2Health News:Free Health Care for the Uninsured Is Coming to Connecticut in February 3Health News:Latest Stunt at Labor Board Shows SEIU's Charges Have No Merit 2Health News:Latest Stunt at Labor Board Shows SEIU's Charges Have No Merit 3Health News:Lotus Pharmaceuticals Announces Key Changes 2Health News:Lotus Pharmaceuticals Announces Key Changes 3Health News:Healthcare Data Services (HDS) Announces Contract with the New England Quality Care Alliance (NEQCA), the Physicians Organization of Tufts Medical Center 2Health News:Healthcare Data Services (HDS) Announces Contract with the New England Quality Care Alliance (NEQCA), the Physicians Organization of Tufts Medical Center 3Health News:McAllister Software Announces PetWise Veterinary Web Site Design and Hosting Service 2Health News:McAllister Software Announces PetWise Veterinary Web Site Design and Hosting Service 3
(Date:6/30/2015)... June 30, 2015  The MEDevice San Diego Conference, ... an event dedicated to bringing medtech professionals together for ... topics affecting the industry today. This year,s conference will ... and opportunities facing today,s medtech professional in a fun, ... register for MEDevice San Diego, please visit: MEDeviceSD.com. ...
(Date:6/30/2015)... , June 30, 2015 Zynerba Pharmaceuticals, Inc. ... Form S-1 with the U.S. Securities and Exchange Commission (SEC) ... stock. The number of shares to be offered and the ... Jefferies LLC and Piper Jaffray & ... and Canaccord Genuity Inc. and Oppenheimer & Co. Inc. will ...
(Date:6/30/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/54fkmt/global_array ... "Global Array Instruments Market 2015-2019" report to ... market to grow at a CAGR of 12.48 ... array instruments market can be divided into three ... tissue microarrays and cell microarrays. This report covers ...
Breaking Medicine Technology:MEDevice San Diego 2015 Attracts High-Tech Medical Industry 2Zynerba Files Registration Statement for Proposed Initial Public Offering of Common Stock 2Global Array Instruments Market 2015-2019 - Advances in Personalized Medicines with Affymetrix, Agilent Technologies & Illumina Dominating 2
... The Apollo Knee System has been ... through range of motion of any fixed ... area and low contact stress under loading ... contributes to long-term effectiveness. The universal symmetrical ...
The Advance revision knee system was designed to address the unpredictable nature of revision knee arthroplasty by providing a wide variety of implant and instrument options....
The AGC dual articular knee is indicated for severe primary or revision cases and features a patented unique articulation which allows controlled rotation of the femoral component about a central piv...
... NexGen CRA femoral component is intended ... anteroposterior, and varus/valgus ligament stability, yet ... to inadequate bone stock. The NexGen ... a PMMA precoat surface. This device ...
Medicine Products: