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Y chromosome uses trick to repair its own genes

of damaged genes that way.

The new work reports evidence that the Y chromosome makes extensive use of a process called gene conversion. The chromosome carries backup copies of its important genes, and it can use one copy to fix a flaw in the other.

The gene-fixing technique comes at a price. When the chromosome makes a mistake in the procedure, it can delete stretches of DNA. Such deletions, occuring in one in every couple thousand boys, are a recognized cause of male infertility.
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