Navigation Links
Wound Healing Accelerated By Mutation In Deafness Gene

Dr. Stella Man, from the Institute of Cell and Molecular Sciences, Queen Mary's University, London, UK, says that a mutation in a gene that is linked to deafness// could have a major part to play in wound healing. Dr Man is to present these findings at the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands today.

This discovery has the potential to be useful in many types of wound healing, including those that are inflicted post-surgically. The team of researchers led by Professor David Kelsell was analyzing the gene (GJB2). A common mutation in this gene is the cause for genetic deafness.

"Since many people carry this mutation", Dr. Man said, "and people who have just one such mutation are not deaf, we felt that there might be some evolutionary advantage to it, so we decided to investigate how the mutation affected the ability of cells to communicate with each other in the epidermis where Cx26 is also expressed."

Cells present in the skin have to have a way of communicating with each other in order to effectively repair and heal wounds. This process involves gap junctions in the skin regulated by proteins called connexins, of which Cx26 is one. "When we looked at the function of Cx26 in a laboratory skin model", said Dr. Man, "we found that it was directly associated with wound healing and bacterial invasion. We concluded that there is a definite advantage to carrying a mutation in this protein."

She added that a drug that can block Cx26 protein in the wound could potentially accelerate healing. "It is interesting to speculate that Cx26 deafness mutations have been selected over the evolutionary process due to their beneficial effects on wound healing."

Contact: Mary Rice

mary@mrcommunication.org

European Society of Human Genetics

Source: Eurekalert


'"/>




Page: 1

Related medicine news :

1. Wound healing made faster
2. Psychological Stress Delays Wound Healing
3. Wound healing affected by Psychological stress
4. Predictors Of Wound Infection In Ventral Hernia Repair
5. Wound Healing Found To Be Slower In Couples Who Fight Often
6. ‘Marriage Squabbles’ bad for both Emotional and Physical Wound
7. Wounds Heal 25% Faster In Older Adults Who Exercise Regularly
8. Honey Works Faster than Antibiotics in Healing Wounds
9. Heroin Injection may Lead to Wound Botulism
10. Nurses Ease the Wounded Heart
11. Guidelines for Chronic Wounds Care
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... , ... October 12, 2017 , ... Planet Fitness, one ... U.S., announced today its plans to open a flagship location in Covington, LA at ... former Rooms To Go store next to Office Depot in the Holiday Square shopping ...
(Date:10/12/2017)... ... , ... Asante, a nationally recognized health system in southern ... home health joint venture through an agreement, effective October 1, 2017, to create ... health company with Asante, delivering clinically integrated care, for the past eight years. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s National ... 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. ... for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... property taxes a year. In some states—like New York, New Jersey, Massachusetts, Texas, ... many overseas retirement havens have extremely low property-tax rates, which contributes to the ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, ... 8th Day Software and Consulting, LLC , and named ... 8th Day Software, based in Tennessee , ... 8th Day expands EnvoyHealth,s service offerings for health care ... "In an interoperable ...
(Date:10/2/2017)... 2017  AllianceRx Walgreens Prime, the combined central specialty ... pharmacy benefit manager Prime Therapeutics LLC (Prime), today officially ... the unveiling of new signage at its headquarters in ... at a few other company-owned facilities across the country. ... some of whom will begin to see the AllianceRx ...
Breaking Medicine Technology: