Navigation Links
Widely Used Hepatitis B Drug Spurs HIV Drug Resistance

ing hepatitis B first,” she adds. Hepatitis B infection attacks the liver and can lead to cirrhosis, liver cancer or even death from liver failure.

Entecavir, first marketed in March 2005, has been a leading treatment for chronic forms of hepatitis B, which can be fatal to almost a quarter of those infected if it is left untreated. The drug’s label information currently states that is has no clinical effects on HIV.

According to Thio, some co-infected patients decide first to treat their hepatitis B infection if HIV has not yet weakened their immune system and to avoid the debilitating side effects of anti-HIV medications.

In the Hopkins study, researchers found in both laboratory and clinical tests that within six months of entecavir therapy, a so-called M184V mutation of HIV develops. Thio says viruses with this mutation are known to be resistant to lamivudine, better known as 3TC, a medication that prevents HIV replication and “is a cornerstone of most drug-combination therapies used to fight the immune system disease.” Because lamivudine is in the same category of HIV therapies as another widely used drug, emtricitabine, its effectiveness is also compromised by entecavir, she says.

Thio began to investigate entecavir’s effects on HIV in fall 2006 after noticing reports of anti-HIV activity in two co-infected patients, one at the Johns Hopkins Moore Clinic, which specializes in HIV/AIDS care, and another at a San Diego medical center. The patients (and there is now a third case) were taking only entecavir yet showed a tenfold decrease in the amount of HIV in their blood.

Previous studies had shown entecavir not to have any significant effects on HIV, but they were based on older tests that could not quantify the effects of HIV on individual immune cells or detect mutations. Thio believed that the recent patient cases called for a more thorough investigation with more advanced techniques.

Sh
'"/>




Page: 1 2 3

Related medicine news :

1. Prescription Drug Use Varies Widely Between States
2. Benefits Of The Worlds Most Widely Used Beverage
3. Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx
4. Breast Cancer Drug Should Be Made Widely Available
5. Widely Prescribed Diabetes Drug Falls Short of Promise, Says New Review
6. Merck Announces Plans for Licensing Atripla Widely in Developing World
7. Vitamin B for Hepatitis
8. Hepatitis G May Boost HIV Survival
9. Cure for Hepatitis B
10. Hepatitis E virus made impotent
11. Sharing injection equipment spreads Hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Widely Used Hepatitis Drug Spurs HIV Drug Resistance

(Date:8/30/2014)... VA (PRWEB) August 30, 2014 Seniors Guide, ... articles recently that focus on Alzheimer’s Disease, Dementia, and ... revealed to the public of being diagnosed with the Alzheimer’s, ... latest movie, “I’ll Be Me”. The movie, out on ... while focusing on his diagnosis of the disease – which ...
(Date:8/30/2014)... Insomnia causes disturbances in every aspect of life. ... insomnia and the steps often used to return back to ... the show at this link: Dr. Carol Francis Talk ... and will be podcasted at this link (Click Here) ... , "Insomnia causes countless unrecognized complications. Weight gain ...
(Date:8/30/2014)... HealthDay Reporter FRIDAY, Aug. 29, 2014 ... for broken bones or other orthopedic trauma shops around for ... Less-educated patients and patients who had used narcotic painkillers previously ... study lead author Dr. Brent Morris, a shoulder and neck ... that doctors aren,t talking to one another about the painkiller ...
(Date:8/30/2014)... 2014 Hastings and Hastings, a qualified ... throughout Arizona is pleased to report having saved a ... example among many cases where Hastings and Hastings has ... retain a greater portion of their settlement or recovery. ... a positive solution for Arizona car accident victims is ...
(Date:8/30/2014)... Administration of colchicine, a plant-based medication commonly used ... showed mixed results in reducing potential complications from ... the risk of gastrointestinal adverse effects, according to ... study is being released early online to coincide ... Cardiology Congress. , Common complications after cardiac surgery ...
Breaking Medicine News(10 mins):Health News:Alzheimer’s Disease and Dementia Focus on Retirement Website SeniorsGuideOnline.com 2Health News:Sleepless Nights, Exhausting Days, Mental Fog – Relief for Insomnia With Clinical Psychologist Dr. Carol Francis 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 3Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2Health News:Medication shows mixed results in reducing complications from cardiac surgery 2
... Wash., March 31 Cardiac Science,Corporation (Nasdaq: ... advanced cardiac diagnosis,resuscitation, rehabilitation, and informatics products, ... Cardiology conference that it completed,certification for its ... Systems. NextGen is a leading developer and ...
... 31 Ingenuity Systems, the,leading provider of ... that Path Designer, the new pathway publishing ... Best New Product by the scientific community ... San Francisco. Path,Designer enables researchers to create ...
... QLT Inc. (NASDAQ: QLTI;,TSX: QLT) announced today the ... phase II trial being conducted by QLT,s wholly-owned,subsidiary, ... preliminary,efficacy and safety of its latanoprost punctal plug ... hypertension. The punctal plug delivery,system is a non-invasive ...
... , , SUNDAY, March 30 (HealthDay News) -- Retired National ... problems, say researchers at the Mayo Clinic in Arizona. ... elite-level football players should begin in high school and ... , The Mayo team examined the cardiovascular health of ...
... findings that could come to define new standards ... conference of the American College of Cardiology, the ... world. These experts will gather beginning this weekend ... advances in cardiovascular medicine, science and education. , ...
... WASHINGTON, March 29 The second annual,National Walk ... National,Mall and raised $1.5 million to help build ... and to raise much-needed funds. The event,was sponsored ... (Photo: http://www.newscom.com/cgi-bin/prnh/20080329/17897 ), The stars ...
Cached Medicine News:Health News:Cardiac Science Adds NextGen to Its Roster of Certified EMR System Partners 2Health News:Cardiac Science Adds NextGen to Its Roster of Certified EMR System Partners 3Health News:Cardiac Science Adds NextGen to Its Roster of Certified EMR System Partners 4Health News:Ingenuity's Path Designer is Selected as Best New Product by Life Science Community at 2008 Molecular Medicine Conference 2Health News:Ingenuity's Path Designer is Selected as Best New Product by Life Science Community at 2008 Molecular Medicine Conference 3Health News:QLT initiates phase II study of punctal plug drug delivery system for glaucoma & ocular hypertension 2Health News:QLT initiates phase II study of punctal plug drug delivery system for glaucoma & ocular hypertension 3Health News:QLT initiates phase II study of punctal plug drug delivery system for glaucoma & ocular hypertension 4Health News:Increased Heart Risk Seen for Retired NFL Players 2Health News:Experts from Penn's School of Medicine to present at ACC Annual Scientific Session 2Health News:Experts from Penn's School of Medicine to present at ACC Annual Scientific Session 3Health News:National Walk for Epilepsy Brings People and Celebrities Together for Epilepsy 2
(Date:8/29/2014)... Aug. 29, 2014 Research and Markets ... Orthopedic Instrument Industry Report, 2014-2017" report to their ... and rising proportion of reimbursement for medical expenses, the ... with its scale presenting a CAGR of 19.2% during ... three product segments of orthopedic instruments in ...
(Date:8/29/2014)... , August 29, 2014 ... Seed Oil Market by Extraction type (SFE, Cold ... & Personal Care, Pharmaceutical, Food Supplements, Fragrance, & Others) ... by MarketsandMarkets, defines and segments the Amaranth Seed ... the market size in terms of value. The ...
(Date:8/29/2014)...  United Therapeutics Corporation (NASDAQ: UTHR ) ... District of New Jersey has ... Sandoz, Inc. regarding United Therapeutics, Remodulin ® product.  In ... U.S. Patent No. 6,765,117 is both valid and enforceable ... generic product until the expiration of that patent in ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4District Court Decision Received In Remodulin Patent Case 2
... bed is especially designed to make your bariatric ... caregivers who manage them. , ,When caring ... pulling up in bed, turning, sitting, standing ... for patients. Excel Care ES bed offers features ...
... Caregiver safety. Patient dignity. A single ... Bariatric Bed to provide added safety where ... is engineered to help protect the caregiver ... efficiency. The bed functions just like other ...
... We offer a wide selection of solutions ... therapy use. The sterile water for inhalation ... in plastic pour bottles in 500 and ... prefilled nebulizer kits or can be used ...
... Nebulizer Disposable Prefilled 28%-100% FIO 2 ... prefilled nebulizers provide unmatched performance and ease of ... aerosols adjustable from 28% to 100% FIO 2 ... sterile water for inhalation, USP; 0.45% sodium chloride ...
Medicine Products: