Navigation Links
Why Are Some People More Depressed Than The Rest When Faced With Similar Situations?

Australian researchers suggest that the answer to the question may lie in one’s genetic make up. They said that some people are genetically predisposed to develop// depression when confronted with stressful life events such as a marriage breakup. The researchers found the influence of adverse life events on the onset of depression was significantly greater for those who inherited a short version of the serotonin transporter gene, known as 5-HTTLPR, from both parents. The individual is more than twice as likely to become depressed as others, given similar circumstances.

Mental health experts conducted the study on 127 graduates from a Sydney teachers' college for the past 25 years. 42 % reported at least one episode of major depression in that time. The researchers compared their DNA profiles with their lifetime history of major stress to find that a particular gene, 5-HTTLPR interacted with the environment to bring on depression. They reported their findings in the British Journal of Psychiatry.

Geneticist Peter Schofield said that those with the genetic predisposition had an 80 % chance of becoming depressed if they had three or more negative events in five years. On the other hand others had only about 30 % chance of developing the mental illness given the similar circumstances.

Lead researcher Kay Wilhelm, of Sydney's St Vincent's Hospital and the University of New South Wales (NSW) said that the current research proved the 2003 New Zealand study which looked at a larger sample of more than 800 people between ages 21 and 26.

The Australian researchers found that about 21 % of their sample, now aged 48, had inherited the short version of the serotonin transporter gene from both parents. Prof Wilhelm, a key researcher at Sydney's Black Dog Institute, said that these genes are less efficient at stopping unwanted emotional messages and hence result in a state of depression.

They produce reduced protein responsible for transporting the brain chemical serotonin, which plays a key role in mood and pain regulation, appetite and sleep. This research is of great significance and one day result in individualized treatments for depression based on a person's genetic makeup.

But Prof Wilhelm warned people against getting their genes checked to assess their susceptibility to depression as it is a very preliminary study. He also said that depression is such a complex condition that the cause was unlikely to be found in just one gene. He said that instead people can be aware of how to handle stress and need to be educated about some relaxation techniques such as meditation.


'"/>




Related medicine news :

1. Bad News for Short People
2. New hope on the Horizon for People Wishing to Quit Smoking
3. Prescription Drug - Helps People Stop Smoking
4. More People Seeking Treatment for Depression
5. Pain Common in People with MS
6. People with skin cancer at higher risk for other types
7. Laser Therapy Found To Help People Quit Smoking
8. Pomegranate Juice May Be The Next Best Thing For People With Heart Disease
9. New Treatment For People Allergic To Cats
10. People who fight wars may be at high risk of cardiovascular disease
11. People suffering from Alzheimer’s: can they take decisions about their treatment
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/25/2016)... ... May 25, 2016 , ... For more than fifty years, we've suffered whiplash as each new ... to conform to the latest nutritional advice – advice that was supposed to keep us ... 2 in 3 American adults are considered to be overweight and more than 1 in ...
(Date:5/25/2016)... FLA (PRWEB) , ... May 25, 2016 , ... ... technology to help turn back the hands of time of female aging. The ... and childbirth. Women with symptoms such as leakage, laxity, itchiness and pain have ...
(Date:5/25/2016)... Aliso Viejo, CA (PRWEB) , ... May 25, 2016 , ... ... will amplify the quality of your footage," said Christina Austin - CEO of Pixel ... Film Studios, editors can quickly and easily add stylish color grades to their footage. ...
(Date:5/25/2016)... ... May 25, 2016 , ... BeniComp Insurance Company, ... spike in their clients' employee participation for their wellness initiatives. BeniComp clients ... a high-deductible health plan with outcome-based deductible incentives. As a result, BeniComp clients ...
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... Researchers from ... Annual COVD Meeting for their work on visual evoked potential and human attention. The ... studies that used the Diopsys® NOVA™ ERG and VEP Vision Testing System ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)...   , Study met both ... superiority in , Excellent plus Good ... of the ascending colon   , ... today announced new positive data from the phase III MORA study ... 2 litre PEG with ascorbate. The study met both primary endpoints ...
(Date:5/24/2016)... 2016  NxStage Medical, Inc. (Nasdaq: NXTM ... renal care, today announced that Jeffrey H. Burbank ... following schedule of investor conferences. Where applicable, a webcast ... http://ir.nxstage.com/ .   ... NY           Friday, June 10, 2016 1:30 p.m. ET ...
(Date:5/24/2016)... The innovator of COMBO ... s first dual therapy stent, introduces catheters for ... OrbusNeich, a global company specializing in the provision of ... products to treat peripheral artery disease. The JADE™ and ... for lower limb and arteriovenous (AV) fistula intervention. ...
Breaking Medicine Technology: