Navigation Links
Wheat Germ Extract Inhibits Breast Cancer in Study

CHICAGO, A fermented wheat germ extract inhibits estrogen positive and estrogen negative breast cancer tumors better than the world's best selling cancer drug, Tamoxifen, according to research published this past weekend at the 2007 meeting of the American Society of Clinical Oncology, ASCO.

The compound, Avemar, has been extensively studied in many cell lines, animal tumor models, and several human clinical trials. In the current study, Andras Telekes, MD, Ph.D., head physician at the Hungarian National Institute of Oncology, and colleagues, implanted estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) breast tumors from humans and mouse cell lines into female mice and monitored tumor growth.

They compared tumor growth in mice treated with Avemar alone, or treated with three of the most widely used and studied breast cancer drugs: Tamoxifen, Aromasin, or Arimidex, alone, and combinations of those drugs with Avemar.

Against the mouse ER+ cell line, MXT, Avemar inhibited growth by 50%, Aromasin by 46.7%, Tamoxifen by 34% and Arimidex by 29.3%. Against the human ER+ cell line, T47T, Avemar inhibited growth by 49%, Tamoxifen 42%, Aromasin 25% and Arimidex 25%. Each agent was enhanced by 5 to 10% when combined with Avemar. Most effective was a combination of Aromasin and Avemar, inhibiting both the mouse and human derived ER+ breast tumors by 60%.

Effects against estrogen receptor-negative (ER-) breast cancer were measured with the human derived, MDA-MB-231 cell line. Estrogen-blocking drugs are not effective against ER- breast cancers, so they were not tested in this tumor model. However, Avemar did inhibit the growth of the ER-negative MDA-MB-231 breast tumors significantly (52%), suggesting to researchers that the mechanism by which the extract works is different from that of the anti- estrogen drugs, and is independent of a breast tumor's estrogen receptor status.

Avemar's effic
'"/>




Page: 1 2

Related medicine news :

1. Wheat wards off colon cancer
2. Earlier Introduction of Solid Foods in Infants Could Prevent Wheat Allergy
3. Wheaton College Affected By Mumps Outbreak
4. Whole Wheat, Wholesome for Pregnant Women and Their Offspring
5. Risk Of Breast Cancer Lowered In Offspring Of Mothers Who Eat Whole Wheat
6. Newly Cloned Wheat Gene May Boosts Foods Nutrient Contents – Says A Researc
7. Improved Wheats Could Reduce Magnesium Deficiencies: Research
8. Ancient Genes Used to Produce Salt-Tolerant Wheat
9. Extracts of grapefruit heals stomach ulcers
10. Yet Another Use For Green Tea Extract
11. Tomato Extract Found To Reduce The Risk Of Thrombosis
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Wheat Germ Extract Inhibits Breast Cancer Study

(Date:7/4/2015)... New York, NY (PRWEB) , ... July 04, 2015 , ... When a hacker gains ... the home front and at the office. On Wednesday, July 1st, the FTC issued ... their credentials as part of a verification process for a password reset instigated by the ...
(Date:7/3/2015)... ... ... The Harvest Hope Food Bank will hopefully be getting a large donation of ... the area of Greenville SC are making it their mission to collect as many canned ... asking for donations from the public as well. As part of the canned food drive, ...
(Date:7/3/2015)... ... July 03, 2015 , ... ... opened registration for a new SEO training system called "Page One Engine" ... organic traffic generation has received glowing reviews from several well-known marketers. HonestyFirstReviews.com's Tiffany ...
(Date:7/3/2015)... ... ... Scientists at several top US cancer centers believe they now know why ... here to read the complete story , just posted on the Surviving Mesothelioma website. ... and New York University exposed mice with a mutation on the tumor suppressor gene ...
(Date:7/3/2015)... ... 03, 2015 , ... B. E. Smith, the only full-service ... a national president recruitment for Regional Care, Inc. in Scottsbluff, Neb. ... Smith has recently placed more than 1,000 healthcare executives into organizations. , ...
Breaking Medicine News(10 mins):Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 2Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 3Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 4Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 2Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 3Health News:Page One Engine - Review Of Dori Friend's SEO Training Course Released 2Health News:Study Finds Small Amounts of Asbestos May Trigger Mesothelioma in People with Genetic Mutation, According to Surviving Mesothelioma 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3
... be fully solved, but scientists are aware that there is ... brain to mature during //the "critical period" when it is ... Scientists say that the senses of vision, hearing and touch ... system provides an exemplary model for studying developmental plasticity, however, ...
... have banned the import of poultry and livestock from bird ... bothered about the spread of bird flu to domestic or ... that bird flu can be transmitted through animals other than ... from one species to another, it is necessary for both ...
... by a bacterium called Helicobacter pylori and can make the ... //The bacterium is also implicated in gastric cancer and causes ... difficult to treat., ,Many approaches have been taken in ... unsuccessful outcomes. In a recent meta-analysis of therapies published in ...
... confirmed that Germany has donated $870,000 to the U.N. ... at youngsters who are out of school in Myanmar. ... to teach youngsters aged 10 and 17 prevention methods ... other skills. The statement added that the program would ...
... The students are caught between the Karnataka state government and ... that the colleges should abide by all conditions put forth ... private medical colleges have challenged the government. The CET Bill ... It was done to put an end to the controversy ...
... who find themselves in a fix, by not able to find ... as mushrooming coffee bars across the country's metros offers them great ... pressure to find a job in China now have a new ... the country's metros. ,According to a survey by China's ...
Cached Medicine News:Health News:Sensory Input Necessary During "Critical Periods" Of Brain Development 2Health News:Sensory Input Necessary During "Critical Periods" Of Brain Development 3Health News:Animal Facts About Bird Flu Transmission 2Health News:Coffee Bars: A Boon For China's Jobless Youths 2
(Date:7/6/2015)... SOUTH SAN FRANCISCO, Calif. , July 6, 2015 ... leading global pharmaceutical company, and Oculeve, a development-stage medical ... eye disease, today announced that they have entered into ... an all-cash transaction.  Under the terms of the agreement, ... payment and commercialization milestone payments related to Oculeve,s lead ...
(Date:7/6/2015)... China , July 6, 2015 China Information ... a leading provider of integrated cloud-based platform, exchange, and ... today announced that the Company launched its mobile app ... of accessible healthcare services on mobile devices. The Company ... Health and Family Planning Bureau and Shenzhen News Net.   ...
(Date:7/4/2015)... 4, 2015 Añadir micro ... de primera línea para pacientes con cáncer colorrectal ... la supervivencia libre de progresión en ese órgano ... no resecable (mCRC) que se ha propagado sólo ... supervivencia libre de progresión (PFS) en el hígado ...
Breaking Medicine Technology:Allergan to Acquire Oculeve Dry Eye Disease Development Programs 2Allergan to Acquire Oculeve Dry Eye Disease Development Programs 3Allergan to Acquire Oculeve Dry Eye Disease Development Programs 4CNIT Launches the Mobile App for Healthcare One Pass 2CNIT Launches the Mobile App for Healthcare One Pass 3CNIT Launches the Mobile App for Healthcare One Pass 4El Congreso Mundial del Cáncer Gastrointestinal presenta nuevos datos del estudio SIRFLOX 2El Congreso Mundial del Cáncer Gastrointestinal presenta nuevos datos del estudio SIRFLOX 3El Congreso Mundial del Cáncer Gastrointestinal presenta nuevos datos del estudio SIRFLOX 4El Congreso Mundial del Cáncer Gastrointestinal presenta nuevos datos del estudio SIRFLOX 5
Adhesive tape sheets for sealing multiwell plates and blocks;...
Microwell Plate Accessories...
DMSO-resistant microplate sealing film...
Amplification Tape 96 featuring 3M adhesive technology. Good optical quality. Minimal autofluorescence. Certified RNase and DNase free....
Medicine Products: