Navigation Links
What Ticks the Mosquito immune system?

A study by researchers at the Johns Hopkins Bloomberg School of Public Health has discovered that mosquitoes utilize similar immune tactics to ward off bacterial// pathogens and plasmodium parasites. The study narrowed down on the different genes connected with the proteins in the immune system of mosquitoes.

All of the immune genes that were involved in limiting infection by the malaria parasites were also important for the resistance to bacterial infection. However, several immune genes that were essential for resistance to bacterial infection did not affect Plasmodium infection. According to the authors, the findings add to the understanding of mosquito immunity, and could contribute towards the development of malaria-control strategies based on blocking the parasite in the mosquito. The study is published in the June 8, 2006, edition of PloS Pathogens.

"Mosquitoes that transmit malaria can kill large portions of Plasmodium parasites, and some mosquito strains are totally resistant to Plasmodium. However, our observations suggest that mosquitoes have not evolved a highly-specific defense against malaria parasites. Instead, they employ factors of their antimicrobial defense system to combat the Plasmodium parasite," said George Dimopoulos, Ph.D., senior author of the study and assistant professor with the Bloomberg School's Malaria Research Institute. "The degree of mosquito susceptibility to Plasmodium, and thereby its capacity to transmit malaria, may therefore partly depend on the mosquito's microbial exposure, which can differ greatly between different geographic sites. Potentially, we could boost the mosquito's capacity to fight the malaria parasite by exposing it to certain microbes or compounds that resemble the microbe molecules responsible for immune activation."

In this study, the investigators also analyzed the immune responses of Anopheles gambiae mosquitoes to infection with different Plasmodium parasite species, on e that causes malaria in humans and another that only infects rodents. The study revealed that mosquitoes mostly employ the same immune factors in defending against the two different Plasmodium species. Only a few immune genes were more important in the defense against either one of the two species.

"The mosquito's immune system appears to employ a variety of antimicrobial defense factors (genes) against the malaria parasite, and can therefore significantly limit infection. The parasite, on the other hand, is capable of evading these defenses to a degree that allows its transmission by the mosquito. Now we have to figure out how to make the mosquito's immune system more effective in killing malaria parasites at multiple stages that would render the development of evasive mechanisms impossible for the parasite," said Dimopoulos.

Source :Eureka


'"/>




Related medicine news :

1. Ticks may cause more diseases
2. Ticks like Sunny Weather
3. Diseases Due To Ticks On the Rise In UK
4. Malaria To Be Tackled By Genetically Modified Mosquitoes
5. India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu
6. Imported Plants Could Deadly Harbor Mosquitoes, Says Report
7. Kids More Prone To Mosquito Bites
8. Mosquito Plague Reported From Western Australia
9. Minister Told To Rid State Of Mosquitoes
10. No Cure for the New Mosquito-Borne Disease, Chikungunya
11. Frog Secretions Could Be Used To Ward Off Mosquitoes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... May 02, 2016 , ... ... event, will be held at the Bellagio Hotel in Las Vegas, NV from ... Work (NASW) will be co-hosting the event. , This year’s conference will offer ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... recently completed two groundbreaking studies that determined that the adjustability and adaptability of ... in the prevention of pressure injuries, which are now referred to as “pressure ...
(Date:5/2/2016)... ... May 02, 2016 , ... Dr. Jonathan Kulbersh of Carolina Facial Plastics isn’t surprised that ... on the list of “ 5 US Cities with the Highest Plastic Rates .” ... Miami. The results were calculated using a survey by RealSelf and combining ...
(Date:5/2/2016)... ... 02, 2016 , ... MedaCheck, a leading medication and disease ... announced its partnership with GrandView Health Services. , With decades of experience, Grandview ... prescription drug pharmacy services to thousands of residents. Serving Indiana, Ohio, Michigan, Tennessee ...
(Date:5/2/2016)... ... , ... The Evolve Paddle Board Company- which specializes in the production and ... their partnership with Yoloha Yoga- producers of high quality cork yoga mats. Together they ... seen a dramatic rise in popularity throughout the last few years. The makers of ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)...  Hologic, Inc. (Nasdaq: HOLX ) ... fiscal second quarter ended March 26, 2016.  GAAP ... 41.2%, and non-GAAP diluted EPS of $0.47 increased ... a reported basis, and 6.3% on a constant ... good quarter, highlighted by 14.6% growth in non-GAAP ...
(Date:4/27/2016)... Italy , April 27, 2016 ... linear accelerator (MR-linac) platform will be the focal point ... meeting of the European Society for Radiotherapy & Oncology, ... Elekta,s MR-linac integrates a state-of-the-art radiotherapy system and a ... physician to clearly see the patient,s anatomy in real ...
(Date:4/27/2016)... 27, 2016  Bayer Animal Health today announced ... the University of Florida College of Veterinary Medicine, ... in Communication Award (BECA). Brittany was selected from ... a total of $70,000 in scholarship funds through ... Bayer has provided a total of $232,500 in ...
Breaking Medicine Technology: