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Ways to Stop Organ Damage When Blood Flow Is Cut Off

nt proteins from damaging tissue.

Fleming's research will be beneficial to those experiencing intestinal ischemia, which she said can have a mortality rate of 70 percent to 100 percent. This research could also help heart attack and hemorrhage victims and those with lupus.

Hemorrhage is similar to ischemia in certain ways, Fleming said. When one part of the body is bleeding profusely, the body directs the blood from the non-vital organs, including the intestines, and sends more blood to the lungs, heart and brain. Because of this, some organs experience ischemia-like conditions when the body hemorrhages.

In addition, the same antibodies that harm tissue after blood flow is resumed are also found in great numbers in people with lupus, an autoimmune disease. Finding ways to curb damage due to the excess antibodies may be part of a cure for this affliction, Fleming said.

"We'd like to find out why someone with an autoimmune disease has these antibodies to begin with," she said.

Students who participate in research with Fleming include Susie Suozzo, senior in biology, Lansing; Lauren Phillips, junior in biology, Olathe; Diane Hylton, sophomore in nutritional sciences, Tecumseh; and Sara Brogan, graduate student in biology, Winfield. Lynn Tustin, research associate, biology, is also involved with the work. Tustin has a doctorate in physiology from K-State.


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