Navigation Links
Waiting for Trial Results Sometimes Unethical

Waiting for the results of randomised trials of public health interventions can cost hundreds of lives, especially in poor countries. Researchers// in this week’s BMJ argue that, if the science is good, we should act before the trials are done.

Randomised controlled trials are usually required before new interventions are implemented. But in 2003, the BMJ published an article about the lack of trials on parachutes to show that situations still exist where such trials are unnecessary.

This week, US researchers use examples from poor countries to show how an overemphasis on randomised controlled trials poses important ethical and logistical problems and may incur avoidable deaths.

In all three examples, the parachute approach has the potential to save tens of thousands of lives, say the authors. For instance, many lives could have been saved if male circumcision had been provided on a large scale from the early 1990s, when data showed that it protected against HIV, instead of waiting 10 to 15 years for more evidence.

Similarly, thousands of women could have been saved if a drug to control blood loss after childbirth was made available in remote areas. But the World Health Organisation has not added it to the essential drugs list because of a lack of evidence from randomised trials in home settings.

The authors stress that randomised controlled trials are needed and, when appropriate, should be part of the empirical evidence necessary for decision making. The question is how much evidence is needed to move from research to practice, when the matter is life saving interventions in poor settings.

The yardstick for decision making should take into account the risks and benefits in the local conditions, not those of an ideal situation, they conclude.

Source-Newswise
SR
'"/>




Page: 1

Related medicine news :

1. Mobile Operating Theater to Cut Waiting Times
2. NHS To Achieve Waiting Figure Target By 2008
3. Gynecologist Solving SuDoKu, While Waiting For Next Patient
4. New Study To Determine "Watchful Waiting" Period For Prostate Cancer
5. 800 People On US Waiting List for AIDS Drugs
6. Funds Pumped In To Reduce Waiting List of Priority Patients
7. UK Patients Seek Fertility Treatment Abroad Due To The Long Waiting List
8. Waiting Period Of Over 10yrs For Women Needing Breast Reduction Surgery
9. Long Patient Waiting Times Force NHS Patients To Seek Treatment Abroad
10. Health Minister Praises Efforts By NHS In Reducing Patient Waiting Time
11. Waiting list in British healthcare causing them to shell out a fortune!
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Waiting for Trial Results Sometimes Unethical

(Date:11/27/2014)... (PRWEB) November 27, 2014 "As a ... embarrassing side effects of urinary incontinence," said an inventor ... and developed this specialized accessory to prevent leakage and ... Incontinence to absorb urine leakage. This prevents stains on ... potential embarrassment. The pad ensures that the individual has ...
(Date:11/27/2014)... THURSDAY, Nov. 27, 2014 (HealthDay News) -- Thanksgiving meals ... eat a gluten-free diet, an expert says. Many ... potatoes and cranberry sauce -- are gluten-free, but "when ... may need to be considered," Dr. Anca Safta, director ... Wake Forest Baptist Medical Center in North Carolina, said ...
(Date:11/27/2014)... York (PRWEB) November 27, 2014 Tylenol ... who were allegedly injured by the medication are continuing ... federal litigation is looking ahead to a status conference ... to a Scheduling Order issued earlier this year, a ... December 16th at 10:00 a.m. Items likely to be ...
(Date:11/27/2014)... Developers and plugin specialist of Final Cut Pro ... FCPX to the next level. , “ProPip allows users to ... of a mouse,” said Christina Austin, CEO of Pixel Film ... appreciate.” , With ProPip users can show off their ... ProPip is great for commentaries, news casting, and more. PROPIP™ ...
(Date:11/27/2014)... to help with chores while they are home from school, ... self-esteem, and above all, helps parents maintain a somewhat tidy ... do you encourage your children to want to help? Is ... Development Journal, there is. The study found that adults’ language ... lend a hand. , The study found that using ...
Breaking Medicine News(10 mins):Health News:Expert Shares Gluten-Free Thanksgiving Tips 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3Health News:Pixel Film Studios released ProPip plugin Exclusively for Final Cut Pro X 2Health News:Pixel Film Studios released ProPip plugin Exclusively for Final Cut Pro X 3
... Centers and free coffee ... give blood, DETROIT, Jan. 8 In honor of ... Cross Donors,Employees and Volunteers in Michigan for two weeks in ... all donors,at any of the participating American Red Cross blood ...
... among 19 countries when it comes to deaths that could ... care, according to new research supported by The Commonwealth Fund ... other nations dramatically improved these rates between 199798 and 200203, ... performed as well as the top three countries out of ...
... States places last among 19 countries when it comes ... to timely and effective health care, according to new ... the January/February issue of Health Affairs. While other nations ... U.S. improved only slightly. , If the U.S. had ...
... government intent on promoting innovation and fuelled by the ... abroad, Chinas health biotech industry only needs a more ... in the production of therapies and medicines both ... new study. , Long considered a skillful product replicator, ...
... for seniors underscore need for Congress to allow price,negotiation, ... 75 percent of Medicare drug plans continue to hike ... of $369 for five,commonly used drugs, between the month ... tracked increased prices on the five drugs by more ...
... NATICK, Mass., Jan. 7 Boston Scientific,Corporation (NYSE: ... for the,Federal Circuit affirmed a District Court ruling which ... patent owned by Johnson & Johnson.,The Appeals Court also ... invalid and affirmed the infringement of that claim. The ...
Cached Medicine News:Health News:Dunkin' Donuts Celebrates the New Year by Supplying Goodies to Michigan's American Red Cross 2Health News:New study: US ranks last among other industrialized nations on preventable deaths 2Health News:US ranks last among other industrialized nations on preventable deaths 2Health News:China's biotech industry: An Asian dragon is growing 2Health News:China's biotech industry: An Asian dragon is growing 3Health News:China's biotech industry: An Asian dragon is growing 4Health News:China's biotech industry: An Asian dragon is growing 5Health News:China's biotech industry: An Asian dragon is growing 6Health News:China's biotech industry: An Asian dragon is growing 7Health News:Most Medicare Drug Plans Continue to Hike Costs into 2008 Two-to-Three Times Rate of Inflation 2Health News:Most Medicare Drug Plans Continue to Hike Costs into 2008 Two-to-Three Times Rate of Inflation 3Health News:Boston Scientific Announces Court Decision 2
(Date:11/26/2014)... , Nov. 26, 2014  Thoratec Corporation (NASDAQ: ... mechanical circulatory support therapies to save, support and restore ... two upcoming investor conferences. On Tuesday, December ... Annual Piper Jaffray Healthcare Conference.  D. Keith ... an update on the company beginning at 11:30 a.m., ...
(Date:11/26/2014)... -- Cohen, Placitella & Roth, PC is investigating potential ... Pharmaceutical Corporation ("Nymox" or "Company") (NASDAQ: ... 2011 through November 2, 2014 ("Class Period").  The ... officers and directors publically disseminated materially false and/or ... 20(a) of the Securities Exchange Act of 1934 ...
(Date:11/26/2014)... Calif. , Nov. 26, 2014  Avanir ... that the U.S. Food and Drug Administration (FDA) ... New Drug Application (NDA) for AVP-825. AVP-825 is ... sumatriptan powder delivered intranasally utilizing a novel Breath ... Complete Response letter, and consistent with the preliminary ...
Breaking Medicine Technology:Thoratec Announces Presentations At Investor Conferences For December 2014 2Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 2Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 2Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 4
... 15, 2011 PDI, Inc. (Nasdaq: ... promotional outsource services to established and emerging health care ... partnership with Qforma, the leading provider of advanced analytics ... Through this agreement, PDI will gain access ...
... REDWOOD CITY, Calif., March 15, 2011 – Ingenuity® ... solutions for life science researchers, today announced new ... in IPA®. Processed RNA-Seq datasets can now be ... context of pathways and diseases for a rich ...
Cached Medicine Technology:PDI Announces Exclusive Partnership With Qforma, Leading Provider of Advanced Analytics for Health Sciences Industry 2Ingenuity Announces RNA-Sequencing Workflow Support and First-of-Its-Kind microRNA Filtering Capability With Latest Release of IPA 2Ingenuity Announces RNA-Sequencing Workflow Support and First-of-Its-Kind microRNA Filtering Capability With Latest Release of IPA 3
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
... special order products are offered as 1-piece ... lengths. The modular instruments may be customized ... such as ratchets, insulation and flush ports. ... stock. Customer specifications may affect delivery times. ...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
... Many special order products are offered as ... long lengths. The modular instruments may be ... options such as ratchets, insulation and flush ... Mediflex stock. Customer specifications may affect delivery ...
Medicine Products: