Navigation Links
Waiting for Trial Results Sometimes Unethical

Waiting for the results of randomised trials of public health interventions can cost hundreds of lives, especially in poor countries. Researchers// in this week’s BMJ argue that, if the science is good, we should act before the trials are done.

Randomised controlled trials are usually required before new interventions are implemented. But in 2003, the BMJ published an article about the lack of trials on parachutes to show that situations still exist where such trials are unnecessary.

This week, US researchers use examples from poor countries to show how an overemphasis on randomised controlled trials poses important ethical and logistical problems and may incur avoidable deaths.

In all three examples, the parachute approach has the potential to save tens of thousands of lives, say the authors. For instance, many lives could have been saved if male circumcision had been provided on a large scale from the early 1990s, when data showed that it protected against HIV, instead of waiting 10 to 15 years for more evidence.

Similarly, thousands of women could have been saved if a drug to control blood loss after childbirth was made available in remote areas. But the World Health Organisation has not added it to the essential drugs list because of a lack of evidence from randomised trials in home settings.

The authors stress that randomised controlled trials are needed and, when appropriate, should be part of the empirical evidence necessary for decision making. The question is how much evidence is needed to move from research to practice, when the matter is life saving interventions in poor settings.

The yardstick for decision making should take into account the risks and benefits in the local conditions, not those of an ideal situation, they conclude.

Source-Newswise
SR
'"/>




Page: 1

Related medicine news :

1. Mobile Operating Theater to Cut Waiting Times
2. NHS To Achieve Waiting Figure Target By 2008
3. Gynecologist Solving SuDoKu, While Waiting For Next Patient
4. New Study To Determine "Watchful Waiting" Period For Prostate Cancer
5. 800 People On US Waiting List for AIDS Drugs
6. Funds Pumped In To Reduce Waiting List of Priority Patients
7. UK Patients Seek Fertility Treatment Abroad Due To The Long Waiting List
8. Waiting Period Of Over 10yrs For Women Needing Breast Reduction Surgery
9. Long Patient Waiting Times Force NHS Patients To Seek Treatment Abroad
10. Health Minister Praises Efforts By NHS In Reducing Patient Waiting Time
11. Waiting list in British healthcare causing them to shell out a fortune!
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... ... May 31, 2016 , ... Secura Consultants ... Louis, Missouri from July 21-23 at the Spazio Westport. The conference is a ... Group financial advisers who work primarily with physicians and professionals in the medical ...
(Date:5/31/2016)... ... 31, 2016 , ... "ProDrop 3D Abstract will spark new innovative ideas for ... Austin - CEO of Pixel Film Studios. , Create an abstract backdrop animation ... ability to generate and manipulate three-dimensional shapes with ease all within Final Cut Pro ...
(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... RF Safe's ... provide the best accessories to avoid excessive Smartphone radiation implicated in the most recent ... released on the bioRxiv preprint server on May 26th (PDF) by the ...
(Date:5/31/2016)... ... May 31, 2016 , ... ... characteristics and the physical and behavioral worlds in which they live, functions ... medicine, diagnosing an individual’s disease depends on accurately assessing his or her ...
(Date:5/31/2016)... ... 2016 , ... Presence Technology , a multi-channel provider ... Gartner, Inc. in the Contact Center Infrastructure Magic Quadrant (*). , Gartner’s May ... of which include: Computer-telephony integration (CTI)/Web services interfaces, Tools for integration with ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... May 31, 2016 The global ... progressing at a CAGR of 10.6% within a forecast ... at US$0.46 bn in 2013. Owing to favorable factors ... reach US$0.88 bn by the end of this forecast ... the market,s holistic representation in a research report published ...
(Date:5/31/2016)... , May 31, 2016 CollPlant Ltd. (TASE: ... rhCollagen technology for tissue repair products - announces that ... Israel,s Ministry of Economy, for ... project for 2016. The Chief Scientist,s grant amount to NIS ... which totaled NIS 4.7 million.  The development ...
(Date:5/30/2016)... 2016 According to ... Market by Technology (Single-factor (Fingerprint, Face, Iris, ... (Workforce Management), End User (Hospitals, Healthcare Institutions) ... MarketsandMarkets, the market is projected to reach ... 1,182.6 Million by 2016, at a CAGR ...
Breaking Medicine Technology: