Navigation Links
WBC linked with periodontitis

A new research has established that a decreased white blood cell function can lead to early-onset periodontal disease, or aggressive periodontitis.The scientists showed that at six weeks of age the// genetically engineered mice had lost 27 percent of their alveolar bone whereas the normal mice had no bone loss. The loss of alveolar bone, which anchors teeth in place, is an indication of periodontitis.

The scientists also supplied evidence that bacteria are necessary to instigate the disease process. To test this theory, they gave antibiotics to some of the knockout mice. The antibiotics reduced the amount of bacteria and eliminated alveolar bone loss in the knockout mice. The scientists said this betokens that bacteria are required for early onset periodontal disease to develop. "We think that the decreased ability of the white blood cells to reach infection sites permits overgrowth of all bacteria, including harmful types," said Dr. Niederman. "Bone loss may be initiated when the amount of harmful bacteria rises above a certain level."

The current research supports on earlier work by the Forsyth team and other scientists who have studied the cellular and molecular basis of aggressive periodontitis. Specifically, the research team is studying the genetics of both the host and the infecting organisms. Working with Dr. Niederman at Forsyth are Dr. Phil Stashenko, Department of Cytokine Biology, and Drs. Floyd Dewhirst and Bruce Paster, Department of Molecular Genetics.


Page: 1

Related medicine news :

1. El Ni?o cycles linked to cholera outbreaks
2. Cancers of Colon & Rectum linked to Cigarette Smoking
3. Gene linked to early puberty in girls
4. Maternal alcohol consumption linked to behavioral problems in children
5. Gene HPA-2 Met linked to cardiac arrest
6. Early puberty linked to nutrition
7. Alcohol linked to brain activity
8. Cement injections linked to osteoporosis
9. Asthma linked to obesity
10. Miscarriage linked to late embryos
11. Cirrhosis linked to genes
Post Your Comments:

(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, ... post-acute health care, have expanded their existing home health joint venture through an ... has been operating a joint venture home health company with Asante, delivering clinically ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, ... a medical article to the newly revamped Cosmetic Town journal section, ... hair transplant procedure known as Follicular Unit Extraction (FUE). , Dr. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts ... Washington, D.C., for the 49th Congress of the International Society of Paediatric Oncology ... of the Center for Cancer and Blood Disorders at Children’s National, and ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017 OBP ... self-contained, illuminating medical devices, today announced regulatory approval ... Surveillance Agency (or Agência Nacional de Vigilância Sanitária ... single-use, cordless surgical retractor with integrated LED light ... access, illumination and exposure of a tissue pocket ...
(Date:10/2/2017)... 2, 2017 The Rebound mobile app is poised ... reverse the tide of prescription drug addiction. The app empowers ... intake and stepping down their dosage in a safe, controlled ... December 2017; the first 100,000 people to sign up will ... ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium , ... File solutions, today—from the IQPC Trial Master Files ... , NL)—announced that EastHORN Clinical Services has selected ... programs and TMF management. EastHORN, a leading European ... platform to increase transparency to enable greater collaboration ...
Breaking Medicine Technology: