Navigation Links
WBC in Lung Produces Histamine: Study

A report on the surprise findings of a study appearing in the January 2007 issue of the Journal of Experimental Medicine, says that scientists have discovered histamine,// the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing.

They say that histamine can be produced in large amounts in the lung by Neutrophils, the White Blood Cells (WBC) that is the major component of pus. Pus, a fluid found in infected tissue, is produced as a result of inflammation.

A study in mice was the first to show that lung neutrophils can produce histamine in significant quantities, according to principal investigator George Caughey, MD, chief of pulmonary/critical care medicine at the San Francisco VA Medical Center.

"Previously it was thought that the primary sources of lung histamine, in health as well as disease, was mast cells, which are classically associated with allergy," notes Caughey, who is also a professor of medicine at the University of California, San Francisco.

Caughey says the result could mean that histamine acts as a link between airway infections and asthma and bronchitis, which are associated with allergy. "In both, we observe inflammation –– swelling, blood vessel leak, and muscle contraction that narrows the airway."

Caughey was investigating the well-known fact that upper respiratory infections often trigger acute asthma attacks. "We hypothesized that an infection in the airway would release histamine from mast cells, and that would be one of the reasons," he explains.

To test the hypothesis, Caughey and his team exposed two different populations of mice to mycoplasma, a common respiratory infection in rodents and humans. One population had a genetic abnormality that causes a total lack of mast cells; the other population was made up of normal, wild-type mice. Both populations of infected mice developed pneumonia.

"We thought the mice witho
'"/>




Page: 1 2 3

Related medicine news :

1. Exposure to Pesticides in Schools Produces Illnesses Among Employees, Students
2. Stress Produces PTSD-like Symptoms in Rats
3. HIV Home-based Care Produces Positive Outcomes in Uganda
4. Research Explains How Lead Exposure Produces Learning Deficits
5. Tomato Sauce reduces Cancer Risk- Study
6. Study on obesity and heart failure
7. National Lung Study in the process
8. Study casts doubt on keyboard ills
9. Study reveals how stress can make you sick
10. Study reveals how stress can make you sick
11. Study supports vegetable diet
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: WBC Lung Produces Histamine Study

(Date:4/17/2014)... Experimental Biology and Medicine a multidisciplinary research ... Kenis in the Institute of Genomic Biology (IGB) ... Urbana-Champaign describe their recent work on subcellular redox ... cell functions including energy metabolism, signaling, and transcriptional ... normal cellular behavior, redox status has been recognized ...
(Date:4/17/2014)... has created a new technology for modifying human ... the body and selectively target cancer and other ... that monitor and modify human physiology is a ... existing technology enabled bioengineers to build such devices ... in a customized fashion. , "The project addressed ...
(Date:4/17/2014)... 17, 2014-- Colic affects about one in five infants ... pediatric visits during the first several months after birth. ... was showing promise; however, the April 1, 2014 issue ... Valerie) reported on a study, "Probiotics and Infant Colic," ... reuteri for infant colic did not reduce ...
(Date:4/17/2014)... off depression among retirees, particularly among those who live ... The Journals of Gerontology, Series B: Psychological Sciences and ... Use and Depression Among Retired Older Adults in the ... that Internet use reduced the probability of a depressed ... , Late-life depression affects between 5 and 10 million ...
(Date:4/17/2014)... therapy improves general blood flow and alleviates muscle ... researchers at the University of Illinois at Chicago. ... print in the Archives of Physical Medicine ... vascular function in people who had not exercised, ... of their level of physical activity. , Improved ...
Breaking Medicine News(10 mins):Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Building 'smart' cell-based therapies 2Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2Health News:Internet use may cut retirees' depression 2Health News:Massage therapy improves circulation, eases muscle soreness 2
... anti-reservation medicos strike in India, the government on Sunday night ... on quota in central educational institutes// but the students and ... by calling a bandh in Delhi on May 31. ... talks with Federal Minister Oscar Fernandes who followed it up ...
... attractive destination for conducting global clinical trials due to ... trained medical professionals and sophisticated technological infrastructure. // ... valued at Rs 3.1 billion in 2005 and is ... Most of the US and European nations are outsourcing ...
... Scientists in the US have created an artificial penis ... and may one day help treat men with severe ... Atala and colleagues at the Wake Forest Institute for ... new method of tissue engineering, reported the online edition ...
... city of Faisalabad have been affected by contaminated water, an ... victims of water-borne diseases, which broke out as a result ... to further increase as more people are being hospitalized., ... affected area is also underway. , ,'we have taken ...
... resolve of the students against reservations who continue their stir ... students tried to self immolate themselves - one in the ... whom the police described as a vendor, tried immolating himself ... gathered in strength, staged a rally protesting against the government's ...
... Geneva - The new interim head of the World Health ... first time since assuming office // , confirmed that Dr ... resources and the support from the people to continue the ... that he would continue the work of his predecessor Dr ...
Cached Medicine News:Health News:Two Students Try To Self-Immolate As Anti-Quota Stir Continues 2Health News:Two Students Try To Self-Immolate As Anti-Quota Stir Continues 3
(Date:1/15/2014)... THOUSAND OAKS, Calif. , Jan. 15, 2014 ... and Amgen (NASDAQ: AMGN ) announced ... to jointly discover and validate new therapeutic targets ... (IBD), a chronic disorder that affects millions worldwide. ...
(Date:1/15/2014)... 2014  Manufacturers, suppliers and distributors of innovative medical-related ... their most important business assets, intellectual property (IP). ... Because of the highly-competitive nature of the ... the most litigious industry sectors of cases involving ...
(Date:1/15/2014)... 15, 2014  Echo Therapeutics, Inc. (Nasdaq: ECTE ... CGM System as a non-invasive, wireless continuous glucose monitoring ... Executive Chairman and Interim CEO of Echo Therapeutics, will ... Equity Conference. Mr. Doman will make ...
Breaking Medicine Technology:Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... The Rogosin Institute is bringing dialysis closer to ... new dialysis center in Auburndale, Queens. The Opening Reception, ... Marshall, Queens Borough President, Paola Miceli, Director, Health, Human ... can accommodate 232 patients. In addition to dialysis, the ...
... 13, 2011 Today, Gil Kerlikowske, Director of National ... of Mothers Against Drunk Driving (MADD) announced a new ... drugged driving.  MADD has launched a national effort to ... and drugs) and drugged driving, and to recognize law ...
Cached Medicine Technology:The Rogosin Institute Opens New Dialysis Center in Queens 2White House Drug Policy Director and Mothers Against Drunk Driving Unite to Combat Drugged Driving; Call on Parents to Act to Reduce Significant Public Safety Threat 2White House Drug Policy Director and Mothers Against Drunk Driving Unite to Combat Drugged Driving; Call on Parents to Act to Reduce Significant Public Safety Threat 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: