Navigation Links
Vulnerability to Ear Infections Lessened by Breast Feeding

Children that are breast fed are able to overcome certain ear infections that occur due to genetic abnormalities.// This was discovered by a group of researchers from the University of Texas Medical Branch at Galveston.

Chronic, recurrent ear infections occur in as many as 19 % children. Ear infections can lead to learning disorders as it interferes with the development of language. Although it was known that ear infections may be caused due to abnormal genes, scientists had not been able to pinpoint which defective genes caused this abnormality. These genes seemed to have a strange complex relationship with environmental factors like smoking and breastfeeding and also with specific infectious agents.

The UTMB study, published in the December issue of the journal Pediatrics, examined genetic samples taken from 505 children in Texas and Kentucky, about 60 percent of whom were classified as "otitis media susceptible" because they had suffered an ear infection before the age of 6 months; had undergone three or more episodes of acute otitis media within a six-month period; had four or more episodes within a 12-month period; or had six or more episodes by age 6. Children who had required drainage tubes to assuage recurrent or persistent ear infections were also placed in the "susceptible" category.

"We know that the tendency to get this infection runs in families, and so we decided to look for small variations — what we call ‘single-nucleotide polymorphisms,' or SNPs — in three important genes that produce inflammatory signaling molecules for the immune system," said lead author Janak A. Patel, a professor in the infectious disease division of UTMB's Department of Pediatrics. "Two of them stood out on their own as signals of increased risk."

The two identified genes generate the immune proteins known as tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6). SNPs in each individual gene were enough, the researchers found, t o create increased risk for childhood ear infections, and simultaneous SNPs in both genes created even more risk. The researchers believe that the particular variations detected cause greater production of inflammatory signaling molecules and reduce immune system effectiveness. But the UTMB scientists found that the effect could be counteracted with a practice long known to increase immune resistance: breast-feeding. "This is a major finding, that breast-feeding neutralized the effect even in kids who had all the genetic polymorphisms," Patel said. "Not only that, they were protected from recurrent infections even later in childhood, long after they stopped breast-feeding." By contrast, the group found that another environmental factor — exposure to cigarette smoke — increased vulnerability to otitis media in children with the TNF-alpha gene variation. Cigarette smoke exposure alone, however, was not enough to increase risk for ear infections.


Related medicine news :

1. Adolescent Smokers Have Greater Vulnerability To AUDs Than Do Non-Smokers
2. Weed Killer Plays a Pivotal Role in Those With Genetic Vulnerability to Parkinson’
3. Supplements for Ear Infections
4. Once-Daily Cipro(R) XR for Treating Complicated Urinary Tract Infections
5. Link Between Ear Infections And Asthma
6. Reducing The Rate Of Infections
7. Good News For Individuals Suffering From Frequent Throat Infections
8. Reducing The Rate Of Hospital Acquired Infections
9. Common Infections Found To Raise An Individuals Risk Of Having A Heart Attack Or Stroke
10. Risk Of Developing Infections High In Patients Who Suffer From Abdominal Trauma
11. Fungal Infections Effectively Controlled By Light Therapy
Post Your Comments:

(Date:11/25/2015)... ... November 25, 2015 , ... Brillianteen, ... friendships, and learning in its 65th Anniversary Brillianteen Revue, scheduled for March 4-6, ... , For 65 years, Brillianteen has been a treasured tradition for numerous families ...
(Date:11/25/2015)... ... November 25, 2015 , ... Castlewood Treatment Center for Eating ... disorders as a result of the $20,000 raised at the center’s recent ... Golf Club in Eureka, will help individuals who otherwise might not seek treatment ...
(Date:11/25/2015)... ... November 25, 2015 , ... An unlikely ... resulting in a way for homeless people to have a more dignified and ... new initiative whereby they are repurposing plastic bags into sleeping mats for the ...
(Date:11/25/2015)... ... November 25, 2015 , ... Students and parents have something to be thankful ... Create Real Impact awards. California Casualty is proud to support the contest ... distracted and reckless driving, the number one killer of young drivers. , Almost ...
(Date:11/24/2015)... , ... November 24, 2015 , ... Dr. Todd S. ... offer laser services to many of his patients. Dr. Afferica now uses the BIOLASE ... reduce the amount of time the doctor uses other traditional cutting tools, such as ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  ARKRAY USA ... continues to provide evidence demonstrating the accuracy of its ... Congress on Insulin Resistance, Diabetes and Cardiovascular Disease in ... both the Company,s GLUCOCARD ® 01 meter and ... accuracy requirements. The ability to accurately measure glucose levels ...
(Date:11/25/2015)... 2015  Trovagene, Inc. (NASDAQ: TROV ), a ... Executive Officer Antonius Schuh, Ph.D., is scheduled to present ... Piper Jaffray Healthcare Conference. th Annual ... Hotel in New York on ... Schuh will be available for one-on-one meetings during the ...
(Date:11/25/2015)... , Nov. 25, 2015 USP ... hazardous drug preparations (e.g. pharmacists, pharmacy technicians, nurses, ... veterinary technicians). The chapter also covers all entities ... (e.g., pharmacies, hospitals, other healthcare institutions, patient treatment ... --> --> What ...
Breaking Medicine Technology: