Navigation Links
Vulnerability to Ear Infections Lessened by Breast Feeding

Children that are breast fed are able to overcome certain ear infections that occur due to genetic abnormalities.// This was discovered by a group of researchers from the University of Texas Medical Branch at Galveston.

Chronic, recurrent ear infections occur in as many as 19 % children. Ear infections can lead to learning disorders as it interferes with the development of language. Although it was known that ear infections may be caused due to abnormal genes, scientists had not been able to pinpoint which defective genes caused this abnormality. These genes seemed to have a strange complex relationship with environmental factors like smoking and breastfeeding and also with specific infectious agents.

The UTMB study, published in the December issue of the journal Pediatrics, examined genetic samples taken from 505 children in Texas and Kentucky, about 60 percent of whom were classified as "otitis media susceptible" because they had suffered an ear infection before the age of 6 months; had undergone three or more episodes of acute otitis media within a six-month period; had four or more episodes within a 12-month period; or had six or more episodes by age 6. Children who had required drainage tubes to assuage recurrent or persistent ear infections were also placed in the "susceptible" category.

"We know that the tendency to get this infection runs in families, and so we decided to look for small variations — what we call ‘single-nucleotide polymorphisms,' or SNPs — in three important genes that produce inflammatory signaling molecules for the immune system," said lead author Janak A. Patel, a professor in the infectious disease division of UTMB's Department of Pediatrics. "Two of them stood out on their own as signals of increased risk."

The two identified genes generate the immune proteins known as tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6). SNPs in each individual gene were enough, the researchers found, t o create increased risk for childhood ear infections, and simultaneous SNPs in both genes created even more risk. The researchers believe that the particular variations detected cause greater production of inflammatory signaling molecules and reduce immune system effectiveness. But the UTMB scientists found that the effect could be counteracted with a practice long known to increase immune resistance: breast-feeding. "This is a major finding, that breast-feeding neutralized the effect even in kids who had all the genetic polymorphisms," Patel said. "Not only that, they were protected from recurrent infections even later in childhood, long after they stopped breast-feeding." By contrast, the group found that another environmental factor — exposure to cigarette smoke — increased vulnerability to otitis media in children with the TNF-alpha gene variation. Cigarette smoke exposure alone, however, was not enough to increase risk for ear infections.



Source-Eurekalert'"/>




Related medicine news :

1. Adolescent Smokers Have Greater Vulnerability To AUDs Than Do Non-Smokers
2. Weed Killer Plays a Pivotal Role in Those With Genetic Vulnerability to Parkinson’
3. Supplements for Ear Infections
4. Once-Daily Cipro(R) XR for Treating Complicated Urinary Tract Infections
5. Link Between Ear Infections And Asthma
6. Reducing The Rate Of Infections
7. Good News For Individuals Suffering From Frequent Throat Infections
8. Reducing The Rate Of Hospital Acquired Infections
9. Common Infections Found To Raise An Individuals Risk Of Having A Heart Attack Or Stroke
10. Risk Of Developing Infections High In Patients Who Suffer From Abdominal Trauma
11. Fungal Infections Effectively Controlled By Light Therapy
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco dentists, ... cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated to ... breathing. Oral appliances can offer significant relief to about 75 percent of people ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ... today the introduction of an innovative new design of the shoulder pad. The ... get maximum comfort while controlling your pain while using cold therapy. By utilizing ice ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical (AVACEN) ... is now successfully helping those with the widespread pain ... Fibromyalgia diagnosed Amanda in Essex, England ... washing my hair, experiencing no sleep at all, tremendous ... spasm… I cannot recommend [the AVACEN 100] enough, how ...
(Date:9/19/2017)... 2017   ZirMed Inc ., a recognized leader in ... it has been ranked #1 by its users for the ... 2017 User Survey. ZirMed was recognized as the top-ranked end-to-end ... medical centers over 200 beds and holds one of the ... survey history. ...
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
Breaking Medicine Technology: