Navigation Links
Vitamins C and E Lowers Kidney Cancer Risk

Increased intake of the antioxidant vitamins C and E could cut the risk of kidney cancer by 28 and 44 per cent, respectively, says a new study from Italy//.

More than 80 per cent of all kidney cancers are accounted for by renal cell carcinoma (RCC). According to the charity Cancer Research UK, kidney cancer is the tenth most common form of the disease, with a male: female incidence ratio of 5:3. In the UK alone, around 6,600 new cases of kidney cancer are diagnosed each year, and the disease results in around 3,600 deaths.

Age, sex, obesity, smoking and several genetic and medical conditions are believed to be risk factors, but epidemiological data to support the role of diet in kidney cancer aetiology have yielded mixed results.

“In the present study, based on a large dataset and with extensive information on major sources of vitamins and micronutrients in the Italian population, an inverse relation was observed between vitamin E and vitamin C intake and RCC risk,” wrote lead author Cristina Bosetti from Milan's Istituto di Ricerche Farmacologiche, “Mario Negri”.

The Multi-Centre Case-Control study, published in the International Journal of Cancer, assessed the dietary intakes of 767 renal cell cancer patients (494 men and 273 women) and 1,534 controls (988 men and 546 women) using a 78-item food frequency questionnaire (FFQ) from which micronutrient intakes were calculated.

After adjusting the results to eliminate possible confounding factors, such as age, BMI, sex, smoking habits and alcohol consumption, the researchers calculated that an intake of more than 17.5 micrograms per day of vitamin E was associated with a 44 per cent reduced risk of renal cell cancer, compared to those with an intake of, on average, 11.9 micrograms.

They also report an intake of more than 186 micrograms per day of vitamin C was associated with a 44 per cent reduced risk of renal cell cancer, compared to those with an int ake of, on average, 89.4 micrograms. This result, said the researchers, was of borderline significance.

No statistically significant association was observed for any of the other micronutrients analysed, including retinol (vitamin A), alpha and beta-carotene, lutein and zeaxanthin, vitamin D, thiamine, folate, and other B vitamins, and lycopene.

“The present findings support a possible beneficial effect of vitamin E and C on RCC,” said the researchers.

The researchers did not investigate the mechanism behind the potential protective effects, but they state that the antioxidant activity of the vitamins could explain the benefits. They do state, however, that since the main sources of vitamin E in the Italian diet are olive oil and vegetables, and may reflect a wider effect of these foods.

“Vitamin E may represent an indirect indicator of a diet rich in vegetables, which are usually consumed with olive oil in this population, and have been related to a reduced risk of RCC,” wrote Bosetti.

“Thus, it is possible that, as for other common neoplasms, the favourable effect of plant food may be due to other still unidentified compounds, or to the complex action of several micronutrients combined.”

The study does have several notable limitations, including relying on food frequency questionnaires to gather dietary information. FAQs are susceptible to recall of the subjects. It is also not known if cases adjusted their diet after diagnosis of their disease.

Source: Bio-Bio Technoloy
SRI
'"/>




Related medicine news :

1. Vitamins-The answer to Heart Disease?
2. Vitamins reduce pre-eclampsia
3. Vitamins enhances recuperation of organ transplant patients
4. Vitamins suppress artery injury after transplant
5. A closer look at Vitamins
6. Prostate cancer and Vitamins
7. Vitamins Harming, not Helping, the Heart
8. How Good Are Vitamins For You ?
9. Vitamins Found To Influence Birth Weight
10. Self-Prescribed Vitamins And Herbal Remedies Can Do More Harm Than Good
11. Pre-eclampsia Pronounced With Intake of Vitamins in Large Doses
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... , ... TherapySites, the leading website and online ... Counseling Association. This new relationship allows TherapySites to continue to extend their ... benefits and promotional offers. , "TCA is extremely excited about this new partnership, ...
(Date:6/26/2016)... ... , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment center ... Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This annual ... the world’s leading providers of cereal and other breakfast foods. Its residents often refer ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the ... AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in ... topics including advance care planning, healthcare costs and patient and family engagement. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events ... turn to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. ... tools for healthy coping following a traumatic event. , Trauma sufferers tend to feel ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... care operating models within the health care industry is ... financial efficiency , Deloitte offers a suite of ... business issues impacting efficient cost optimization: labor resource analysis, ... These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... , June 24, 2016   Bay Area ... Network,s Dean Center for Tick Borne Illness ... and Rehabilitation, MIT Hacking Medicine, University of California, ... today announced the five finalists of Lyme ... disease.  More than 100 scientists, clinicians, researchers, entrepreneurs, ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
Breaking Medicine Technology: