Navigation Links
Vision restoration with a drug for macular degeneration

A recent research proposes that the drug used to treat wet age-related macular degeneration (wet AMD) could also aid in improvement of vision in some people. //

Wet AMD is the biggest cause of loss of vision in the UK. Sight can be regained to some extent in people with a specific type of retina degeneration by giving injections of the drug Lucentis.

The study was published in the New England Journal of Medicine. The research involved 716 patients who were given eye chart tests before and after receiving the drug or a placebo. It was found that sight loss was slowed down in 9 out of 10 patients and improvement in vision in about 1/3rd of those who received the drug. However, slowing down of sight loss was observed in only 5 out of 10 patients who received a placebo.

After 2 years of treatment, 9 out of 10 of those given the drug lost less than 15 of the letters on the chart when compared to 5 out 10 in case of those receiving a placebo. Improvement in vision was observed in 26% of those receiving 0.3mg of the drug and 33% of those receiving 0.5mg compared to 4% on the placebo. This revealed that they could read an additional three lines or 15 or more letters on an eye chart after a course of treatment.

Lucentis (ranibizumab), is used to treat wet AMD. It has been approved for use in the U.S. but yet to be approved in Europe. The National Institute for Health and Clinical Excellence (NICE) should evaluate this drug. Ranibizumab belongs to the class known as anti-angiogenics. It prevents the formation of abnormal, new blood vessels in the eye, and dries up previously leaking vessels.

Steve Winyard, of the Royal National Institute for the Blind (RNIB), said, "The results were very exciting". He added: "Thousands of people a year in the UK get wet AMD and it rapidly leads to sight loss. This drug is particularly exciting because it can treat all types of AMD. Although this is not a cure, ranibizumab is great news for individual patients as it offers them the chance of having their vision restored."

A major cause of blindness in UK is the wet AMD. Thousands of new cases are reported every year. In UK, nearly 5,00,000 people are affected by wet and dry forms of AMD with 20,000 of them accounting for the wet form. The wet form is responsible for 90% of the cases of blindness due to this disorder. In this condition, new blood vessels are formed behind the retina causing bleeding and scarring. Increasing age, smoking and genetic factors are considered to increase the risk of AMD.

Winfried Amoaku, a consultant ophthalmologist and member of the Royal College of Ophthalmologists' scientific committee, said: "This study on Lucentis is the first to show vision improvement in patients with wet AMD. "Previous studies have demonstrated that other treatments can help maintain vision. However, there is no data directly comparing Lucentis to other similar treatments. Another drug, Macugen, and photodynamic therapy can halt the advance of AMD. And there is preliminary evidence that Avastin, a drug used to treat cancer, may also potentially restore vision in a way similar to Lucentis."

The Macular Disease Society said, "It is vital Lucentis is granted a Europe-wide licence and treatment is funded by the NHS as soon as possible. It is a treatment that is effective within the first few weeks of onset of Wet AMD. If funding by primary care trusts is delayed until Nice complete their review then thousands of people could lose their sight irreversibly."
GYT
'"/>




Related medicine news :

1. Genes for Vision discovered
2. Vision loss could result due to MSG
3. Preventing Vision Loss
4. Preventing Vision Loss
5. Prevention of Vision Loss
6. Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern
7. Impotence drug such as Viagra may cause Vision Loss
8. Vision Loss in Elderly Caused By Combined Effect of Genes and Bacterium
9. Glaucoma Could Cause Vision Loss In 60 Million People By 2010
10. UV Rays Affects the Power of Vision
11. Aids Seems More Prevalent Among Goan’s – Governor Visiond
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... in Dallas that it will receive two significant new grants to support its ... PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists for ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway ... call for a minimum wage raise to $12 an hour by 2020 and then adjusting ... restore the lost value of the minimum wage, assure the wage floor does not erode ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... their offering. The current ... environment for MedImmune to enter. The US ageing population creates ... drive considerable growth for effective anti-influenza medications. The introduction of ... but development is still in its infancy. ...
Breaking Medicine Technology: