Navigation Links
Vision Loss in Elderly Caused By Combined Effect of Genes and Bacterium

A definitive link has been established between age-related macular degeneration and the genetic mechanisms underlying the disease process. The finding has been confirmed by the identification of a bacterium //called Chlamydia pneumoniae in the diseased tissue of the affected individuals. It is also notable that the microorganism is associated with chronic inflammation and heart disease.

Researchers found C. pneumoniae in the diseased eye tissue of five of nine people with wet AMD. People without AMD (20) were however devoid of the microorganism and infection. Hence it is very possible that the disease itself is the result of an inflammatory process.

The microorganism C. pneumoniae is capable of modifying the function of important cell types involved in regulating normal eye function. Furthermore, the infection was associated with an increased production of vascular endothelial growth factor (VEGF), the key protein involved in wet AMD.

Researchers believe that nearly half of AMD cases can be explained by variations in a gene called Complement Factor H (CFH). The gene is known to play a significant role in the regulation of the natural immune and inflammatory response.

It is hence hypothesized that C. pneumoniae may be the key link between CFH and AMD, meaning that people who have different genetic constitution with respect to the CFH can be particularly susceptible to infections caused by the organism.

The increased susceptibility to infections followed by the presence of a chronic infection may accelerate inflammation and hence the progression of AMD in a certain groups of patients.

Further research is needed in the same direction to unravel the mysteries associated with the disease, which can help in better diagnosis and management.


'"/>




Page: 1

Related medicine news :

1. Genes for Vision discovered
2. Vision loss could result due to MSG
3. Preventing Vision Loss
4. Preventing Vision Loss
5. Prevention of Vision Loss
6. Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern
7. Impotence drug such as Viagra may cause Vision Loss
8. Glaucoma Could Cause Vision Loss In 60 Million People By 2010
9. UV Rays Affects the Power of Vision
10. Aids Seems More Prevalent Among Goan’s – Governor Visiond
11. Save your Vision with Fish Oil and Quitting Smoking
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica ... Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs ... Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, ...
(Date:6/25/2016)... ... , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors ... Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green ... hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... are unfamiliar with. The article goes on to state that individuals are now more ... these less common operations such as calf and cheek reduction. The Los Angeles area ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Scientific Sessions in Dallas that it will receive two significant new grants to ... came as PHA marked its 25th anniversary by recognizing patients, medical professionals and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... OAKLAND, N.J. , June 24, 2016 /PRNewswire/ ... in the design, development and manufacturing of collagen ... and regeneration announced today that Bill Messer ... Sales and Marketing to further leverage the growing ... surgery medical devices. Bill joins the ...
(Date:6/24/2016)... June 24, 2016   Bay Area Lyme ... Dean Center for Tick Borne Illness , ... Rehabilitation, MIT Hacking Medicine, University of California, Berkeley, ... announced the five finalists of Lyme Innovation ... More than 100 scientists, clinicians, researchers, entrepreneurs, and ...
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
Breaking Medicine Technology: