Navigation Links
Vision Loss in Elderly Caused By Combined Effect of Genes and Bacterium

A definitive link has been established between age-related macular degeneration and the genetic mechanisms underlying the disease process. The finding has been confirmed by the identification of a bacterium //called Chlamydia pneumoniae in the diseased tissue of the affected individuals. It is also notable that the microorganism is associated with chronic inflammation and heart disease.

Researchers found C. pneumoniae in the diseased eye tissue of five of nine people with wet AMD. People without AMD (20) were however devoid of the microorganism and infection. Hence it is very possible that the disease itself is the result of an inflammatory process.

The microorganism C. pneumoniae is capable of modifying the function of important cell types involved in regulating normal eye function. Furthermore, the infection was associated with an increased production of vascular endothelial growth factor (VEGF), the key protein involved in wet AMD.

Researchers believe that nearly half of AMD cases can be explained by variations in a gene called Complement Factor H (CFH). The gene is known to play a significant role in the regulation of the natural immune and inflammatory response.

It is hence hypothesized that C. pneumoniae may be the key link between CFH and AMD, meaning that people who have different genetic constitution with respect to the CFH can be particularly susceptible to infections caused by the organism.

The increased susceptibility to infections followed by the presence of a chronic infection may accelerate inflammation and hence the progression of AMD in a certain groups of patients.

Further research is needed in the same direction to unravel the mysteries associated with the disease, which can help in better diagnosis and management.


'"/>




Page: 1

Related medicine news :

1. Genes for Vision discovered
2. Vision loss could result due to MSG
3. Preventing Vision Loss
4. Preventing Vision Loss
5. Prevention of Vision Loss
6. Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern
7. Impotence drug such as Viagra may cause Vision Loss
8. Glaucoma Could Cause Vision Loss In 60 Million People By 2010
9. UV Rays Affects the Power of Vision
10. Aids Seems More Prevalent Among Goan’s – Governor Visiond
11. Save your Vision with Fish Oil and Quitting Smoking
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced ... attorneys chosen by their peers for this recognition are considered among the top 2 ... received special honors as members of this year’s Legal Elite Hall of Fame: ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their ... Award, an essay contest in which patients and their families pay tribute to a ... the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, ... -based mobile pulmonary function testing company, is now able to perform ... developed by ndd Medical Technologies , Inc. ... in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL ... can get any needed testing done in the comfort of her ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ... company developing innovative inhaled drugs, announced today that it ... Russell Investments reconstituted its comprehensive set of U.S. ... "This is an important milestone for Pulmatrix," said ... increase shareholder awareness of our progress in developing drugs ...
Breaking Medicine Technology: